The contribution of copy number variation to obesity — a highly heritable and genetically heterogeneous disorder — is investigated in 300 Caucasian patients to reveal that large, rare deletions are significantly enriched in patients compared to controls. Several rare copy number variants are identified that are recurrent in patients but absent or at much lower prevalence in controls.
- Elena G. Bochukova
- Ni Huang
- I. Sadaf Farooqi
