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Showing 1–2 of 2 results
Advanced filters: Author: Samantha B. Bremner Clear advanced filters
  • This paper highlights the far-red chemigenetic H2O2 reporter oROS-HT635, which enables detailed insights into intricate intracellular and intercellular H2O2 dynamics, along with their environmental interactants, through spatially resolved, multiplexed real-time H2O2 imaging.

    • Justin Daho Lee
    • Amanda Nguyen
    • Andre Berndt
    Research
    Nature Chemical Biology
    P: 1-12
  • Fluorescent protein reporters based on GFP exist, but have intrinsic disadvantages. Here the authors incorporate pH, Ca2+ and protein–protein interaction sensing modalities into de novo designed mini-fluorescence-activating proteins (mFAPs), with increased photostability and smaller size, which bind a range of DFHBI chromophore variants.

    • Jason C. Klima
    • Lindsey A. Doyle
    • David Baker
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-19