Nature Search

The changing landscape of cancer cell therapies: clinical trials and real-world data

Ana Rosa Saez-Ibañez
Samik Upadhaya
Jay Campbell
Comments & Opinion31 May 2024
Nature Reviews Drug Discovery

Volume: 23, P: 736-737
Formation and current-induced motion of synthetic antiferromagnetic skyrmion bubbles

Realizing stable, room-temperature magnetic skyrmions that can be moved along current is challenging. Here, the authors observe skyrmion bubbles in a synthetic antiferromagnetic coupled multilayer at room temperature and demonstrate its current-induced motion free from the skyrmion Hall effect.

Takaaki Dohi
Samik DuttaGupta
Hideo Ohno
ResearchOpen Access14 Nov 2019
Nature Communications

Volume: 10, P: 1-6
Magnetization switching by spin–orbit torque in an antiferromagnet–ferromagnet bilayer system

Antiferromagnet/ferromagnet bilayers are shown to exhibit large enough spin–orbit torque to switch the magnetization of the ferromagnetic layer without the application of external magnetic fields.

Shunsuke Fukami
Chaoliang Zhang
Hideo Ohno
Research15 Feb 2016
Nature Materials

Volume: 15, P: 535-541
Landscape of cancer cell therapies: trends and real-world data

Ana Rosa Saez-Ibañez
Samik Upadhaya
Jay Campbell
Comments & Opinion01 Jun 2022
Nature Reviews Drug Discovery

Volume: 21, P: 631-632
Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells

A muscle autoimmune disease is treated in mice with CAAR T cells.

Sangwook Oh
Xuming Mao
Aimee S. Payne
ResearchOpen Access19 Jan 2023
Nature Biotechnology

Volume: 41, P: 1229-1238
A phase 2 single center open label randomised control trial for convalescent plasma therapy in patients with severe COVID-19

Convalescent plasma therapy (CPT) is used to treat patients with Covid-19, but evidence for clinical benefit from clinical trials is divergent. Here the authors report in that CPT treatment does not affect mortality in patients with severe Covid-19 in phase 2 single center open label randomised controlled trial.

Yogiraj Ray
Shekhar Ranjan Paul
Dipyaman Ganguly
ResearchOpen Access19 Jan 2022
Nature Communications

Volume: 13, P: 1-9
Cellular anatomy of the mouse primary motor cortex

Multi-modal analysis is used to generate a 3D atlas of the upper limb area of the mouse primary motor cortex, providing a framework for future studies of motor control circuitry.

Rodrigo Muñoz-Castañeda
Brian Zingg
Hong-Wei Dong
ResearchOpen Access06 Oct 2021
Nature

Volume: 598, P: 159-166
Population diversity in immuno-oncology trials

Ana Rosa Saez-Ibanez
Samik Upadhaya
Jay Campbell
News08 Nov 2022
Nature Reviews Drug Discovery

Volume: 21, P: 870-871
The clinical pipeline for cancer cell therapies

Samik Upadhaya
Jia Xin Yu
Jay Campbell
Comments & Opinion04 Jun 2021
Nature Reviews Drug Discovery

Volume: 20, P: 503-504
Challenges and opportunities in the PD1/PDL1 inhibitor clinical trial landscape

Samik Upadhaya
Svetoslav T. Neftelinov
Jay Campbell
News10 Feb 2022
Nature Reviews Drug Discovery

Volume: 21, P: 482-483
Naturally-primed life strategy plasticity of dimorphic Aethionema arabicum facilitates optimal habitat colonization

Samik Bhattacharya
Katja Sperber
Klaus Mummenhoff
ResearchOpen Access06 Nov 2019
Scientific Reports

Volume: 9, P: 1-11
Noninvasive, label-free image approaches to predict multimodal molecular markers in pluripotency assessment

Ryutaro Akiyoshi
Takeshi Hase
Ayako Yachie
ResearchOpen Access09 Jul 2024
Scientific Reports

Volume: 14, P: 1-14
Software for systems biology: from tools to integrated platforms

Systems biology is intrinsically reliant on software tools and data resources. Through looking at each stage in a systems biology workflow, this Review presents the available options and key challenges, and sets out the concept of an integrated software platform.

Samik Ghosh
Yukiko Matsuoka
Hiroaki Kitano
Reviews03 Nov 2011
Nature Reviews Genetics

Volume: 12, P: 821-832
Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer

Pallab Ray
Deblina Guha
Gaurisankar Sa
ResearchOpen Access13 Sept 2016
Scientific Reports

Volume: 6, P: 1-11
Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology

Takahiro Amemiya
Masashi Honma
Hiroshi Suzuki
ResearchOpen Access28 Sept 2015
npj Systems Biology and Applications

Volume: 1, P: 1-10
Unobtrusive measurement of cognitive load and physiological signals in uncontrolled environments

Christoph Anders
Sidratul Moontaha
Bert Arnrich
ResearchOpen Access13 Sept 2024
Scientific Data

Volume: 11, P: 1-16
Activation of c-Met in cancer cells mediates growth-promoting signals against oxidative stress through Nrf2-HO-1

Samik Chakraborty
Murugabaskar Balan
Soumitro Pal
ResearchOpen Access15 Jan 2019
Oncogenesis

Volume: 8, P: 1-12

Search

The changing landscape of cancer cell therapies: clinical trials and real-world data

Formation and current-induced motion of synthetic antiferromagnetic skyrmion bubbles

Magnetization switching by spin–orbit torque in an antiferromagnet–ferromagnet bilayer system

Landscape of cancer cell therapies: trends and real-world data

Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells

A phase 2 single center open label randomised control trial for convalescent plasma therapy in patients with severe COVID-19

Cellular anatomy of the mouse primary motor cortex

Population diversity in immuno-oncology trials

The clinical pipeline for cancer cell therapies

Challenges and opportunities in the PD1/PDL1 inhibitor clinical trial landscape

Naturally-primed life strategy plasticity of dimorphic Aethionema arabicum facilitates optimal habitat colonization

Noninvasive, label-free image approaches to predict multimodal molecular markers in pluripotency assessment

Software for systems biology: from tools to integrated platforms

Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer

Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology

Unobtrusive measurement of cognitive load and physiological signals in uncontrolled environments

Activation of c-Met in cancer cells mediates growth-promoting signals against oxidative stress through Nrf2-HO-1

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