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Showing 1–3 of 3 results
Advanced filters: Author: Sandra M. Fernández-Moya Clear advanced filters

  • Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, contributing to the study of post-transcriptional gene regulation in individual cells.

    • Franz Ake
    • Marcel Schilling
    • Mireya Plass
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17

  • Synaptic activity controls the extinction of conditioned fear. Here the authors discovered a new way that the brain controls memories of fear: a long noncoding RNA called Gas5 that coordinates the activity of RNA granules in the synaptic compartment.

    • Wei-Siang Liau
    • Qiongyi Zhao
    • Timothy W. Bredy
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16

  • Asymmetric subcellular mRNA distribution is important for local translation of neuronal mRNAs. Here the authors employed MS2 live-cell imaging and showed that the reporter mRNA containing the 3’ UTR of Rgs4 shows an anterograde transport bias, dependent on neuronal activity and the protein Staufen2, and mediates sustained mRNA recruitment to synapses.

    • Karl E. Bauer
    • Inmaculada Segura
    • Michael A. Kiebler
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13