NLRP3-Caspase1-IL-18 pathway becomes activated in the esophageal epithelial cells and macrophages following allergen exposure, leading to EoE initiation. Pharmacological inhibitors are novel treatment strategies for EoE pathogenesis
- Chandra Sekhar Yadavalli
- Sathisha Upparahalli Venkateshaiah
- Anil Mishra