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Showing 1–7 of 7 results
Advanced filters: Author: Scott Trappe Clear advanced filters

  • Reticular frameworks are crystalline porous materials with desirable properties such as gas separation, but their large design space presents a challenge. An automated nanoporous materials discovery platform powered by a supramolecular variational autoencoder can efficiently explore this space.

    • Zhenpeng Yao
    • Benjamín Sánchez-Lengeling
    • Alán Aspuru-Guzik
    Research
    Nature Machine Intelligence
    Volume: 3, P: 76-86

  • Temporal multi-omic analysis of tissues from rats undergoing up to eight weeks of endurance exercise training reveals widespread shared, tissue-specific and sex-specific changes, including immune, metabolic, stress response and mitochondrial pathways.

    • David Amar
    • Nicole R. Gay
    • Elena Volpi
    ResearchOpen Access
    Nature
    Volume: 629, P: 174-183

  • It is known that exercise influences many human traits, but not which tissues and genes are most important. This study connects transcriptome data collected across 15 tissues during exercise training in rats as part of the Molecular Transducers of Physical Activity Consortium with human data to identify traits with similar tissue specific gene expression signatures to exercise.

    • Nikolai G. Vetr
    • Nicole R. Gay
    • Stephen B. Montgomery
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Exerkines are signalling moieties that are released in response to acute and/or chronic exercise that exert their effects through endocrine, paracrine and/or autocrine pathways. This Review summarizes the importance and current state of exerkine research, prevailing challenges and future directions.

    • Lisa S. Chow
    • Robert E. Gerszten
    • Michael P. Snyder
    Reviews
    Nature Reviews Endocrinology
    Volume: 18, P: 273-289