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Showing 1–2 of 2 results
Advanced filters: Author: Shany Picciotto Clear advanced filters

  • Mutations accumulate with age in the male germline, and can lead to genetic diseases in offspring. Here, the authors collect from individuals sequential sperm samples separated by long timespans, which they profile by high-fidelity sequencing to study germline mutation processes.

    • Jonathan E. Shoag
    • Amoolya Srinivasa
    • Gilad D. Evrony
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • A DNA sequencing method with single-molecule fidelity detects mismatches and damage present in only one of the two DNA strands with patterns that are both similar and distinct compared to known mutation patterns.

    • Mei Hong Liu
    • Benjamin M. Costa
    • Gilad D. Evrony
    Research
    Nature
    Volume: 630, P: 752-761