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Showing 1–2 of 2 results
Advanced filters: Author: Shenduo Li Clear advanced filters

  • The approval of first line immune checkpoint blockade (ICB) has improved outcomes for patients with metastatic non-small cell lung cancer (mNSCLC), however, whether patients would benefit more from ICB alone or alongside chemotherapy is unclear. Here, the authors develop a machine-learning based approach to help guide individual treatment selection patients with mNSCLC.

    • Maliazurina B. Saad
    • Qasem Al-Tashi
    • Jia Wu
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11

  • Immune checkpoint inhibitors with or without chemotherapy are now standard of care for non-small cell lung cancer. However, the benefits of combination vs sequential therapy have not been fully explored. Here, the authors analysed 1,133 patient records and show combination therapy showed increased protection against early progression, but similar overall survival.

    • Lingzhi Hong
    • Muhammad Aminu
    • Natalie I. Vokes
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15