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Engineering virus-like particles for safe and versatile modeling of SARS-CoV-2 host interaction and immune escape

A trVLP system based on Sindbis virus and pseudotyped with SARS-CoV-2 RBD enables rapid dissection of ACE2 binding and SARS-CoV-2 immune escape mutations, supporting host-range and viral evolution studies.

Liang Ma
Yuan Lin
Yihan Lin
ResearchOpen Access30 Aug 2025
Communications Biology

Volume: 8, P: 1-13
Integration of high strength, flexibility, and room-temperature plasticity in ceramic nanofibers

Ceramics are typically limited by inherent brittleness and weak deformability. Here, the authors synthesize crystalline/amorphous dual-phase ceramic nanofibers, integrating high strength, superior flexibility, and room-temperature plasticity.

Siyu Qiang
Fan Wu
Bin Ding
ResearchOpen Access05 Apr 2025
Nature Communications

Volume: 16, P: 1-12
Unraveling morphological brain network disparities Parkinsonian tremor from essential tremor: an artificial intelligence approach for clinical differentiation

Moxuan Zhang
Siyu Zhou
Fangang Meng
ResearchOpen Access22 Aug 2025
npj Parkinson's Disease

Volume: 11, P: 1-12
A MaxEnt-TRIGRS hybrid model with dynamic safety factor mapping for enhanced debris flow susceptibility assessment in rainfall-triggered terrains

Xinlong Xu
Yue Qiang
He Yang
ResearchOpen Access19 Jul 2025
Scientific Reports

Volume: 15, P: 1-22
A potent broad-spectrum neutralizing antibody targeting a conserved region of the prefusion RSV F protein

In this study, the authors report a potent neutralizing antibody targeting a conserved epitope within RSV pre-F that shows higher antiviral activity against both RSV-A and -B subgroups in vitro and in small animal models than FDA-approved prophylactic agents.

Yongpeng Sun
Liqin Liu
Ningshao Xia
ResearchOpen Access21 Nov 2024
Nature Communications

Volume: 15, P: 1-16
Control of arbuscule development by a transcriptional negative feedback loop in Medicago

Zhang et al. report that Medicago AR2/ERF transcription regulators WRI5a-ERM1-ERF12 form a transcriptional negative feedback loop to coordinate arbuscular lipid supply, enabling the maintenance of a stable, reciprocally beneficial symbiosis.

Qiang Zhang
Shuangshuang Wang
Yina Jiang
ResearchOpen Access16 Sept 2023
Nature Communications

Volume: 14, P: 1-14
ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression

The accumulation of myeloid derived suppressor cells (MDSC) has been associated with prostate cancer progression and castration resistance. Here the authors show that loss of ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, results in polymorphonuclear-MDSC infiltration and cooperates with Pten loss to accelerate prostate tumorigenesis.

Ni Li
Qiuli Liu
Jun Qin
ResearchOpen Access26 Nov 2022
Nature Communications

Volume: 13, P: 1-20
Prevalence of diabetic retinopathy and vision-threatening diabetic retinopathy in adults with diabetes in China

Current data on the national distribution of diabetic retinopathy (DR) is lacking. Here, the authors show the national distribution, associated multi-level factors, and visual impairment of DR and vision-threatening DR in Chinese adults with diabetes.

Xuhong Hou
Limin Wang
Weiping Jia
ResearchOpen Access18 Jul 2023
Nature Communications

Volume: 14, P: 1-11
Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24

Stat6 promotes M2 macrophage polarization. Here the authors characterize Trim24-CBP-Stat6 circuit regulating M2 macrophage polarization via Stat6 acetylation, and show it contributes to pro-tumorigenic macrophage activity in mice.

Tao Yu
Shucheng Gan
Yichuan Xiao
ResearchOpen Access25 Sept 2019
Nature Communications

Volume: 10, P: 1-15
Efficient access to aliphatic esters by photocatalyzed alkoxycarbonylation of alkenes with alkyloxalyl chlorides

Aliphatic esters are essential constituents of biologically active compounds but their preparation from readily available olefins remains challenging. Here the authors show a strategy to access aliphatic esters from olefins through a unique photocatalyzed alkoxycarbonylation reaction.

Jian-Qiang Chen
Xiaodong Tu
Jie Wu
ResearchOpen Access07 Sept 2021
Nature Communications

Volume: 12, P: 1-15
FTDC1/2, oocyte-specific cofactors of DNMT1 required for epigenetic regulation and embryonic development

Congyang Li
Jiashuo Li
Qiang Wang
Research28 Apr 2025
Cell Death & Differentiation

P: 1-18
SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation

Regulatory T cells are crucial for the establishment and maintenance of peripheral immune tolerance, yet the mechanisms regulating their stability and function remain to be fully elucidated. Here the authors show SENP3 maintains Treg cell stability and function via BACH2 deSUMOylation.

Xiaoyan Yu
Yimin Lao
Qiang Zou
ResearchOpen Access08 Aug 2018
Nature Communications

Volume: 9, P: 1-11
Exploring the potential mechanisms of Danshen against COVID-19 via network pharmacology analysis and molecular docking

Qiang Zhang
Zongsuo Liang
Zongqi Yang
ResearchOpen Access04 Jun 2024
Scientific Reports

Volume: 14, P: 1-17
RETRACTED ARTICLE: Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C4

Tianzhen Hu
Chengyun Pan
Qin Fang
ResearchOpen Access15 Jul 2022
Cancer Gene Therapy

Volume: 29, P: 1773-1790
Stability analysis of rainfall-induced landslide considering air resistance delay effect and lateral seepage

Li Li
Hanjie Lin
Bo Ni
ResearchOpen Access10 Apr 2024
Scientific Reports

Volume: 14, P: 1-10
The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals

Yanan Cao
Lin Li
Mengyao Wang
ResearchOpen Access30 Apr 2020
Cell Research

Volume: 30, P: 717-731

Search

Engineering virus-like particles for safe and versatile modeling of SARS-CoV-2 host interaction and immune escape

Integration of high strength, flexibility, and room-temperature plasticity in ceramic nanofibers

Unraveling morphological brain network disparities Parkinsonian tremor from essential tremor: an artificial intelligence approach for clinical differentiation

A MaxEnt-TRIGRS hybrid model with dynamic safety factor mapping for enhanced debris flow susceptibility assessment in rainfall-triggered terrains

A potent broad-spectrum neutralizing antibody targeting a conserved region of the prefusion RSV F protein

Control of arbuscule development by a transcriptional negative feedback loop in Medicago

ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression

Prevalence of diabetic retinopathy and vision-threatening diabetic retinopathy in adults with diabetes in China

Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24

Efficient access to aliphatic esters by photocatalyzed alkoxycarbonylation of alkenes with alkyloxalyl chlorides

FTDC1/2, oocyte-specific cofactors of DNMT1 required for epigenetic regulation and embryonic development

SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation

Exploring the potential mechanisms of Danshen against COVID-19 via network pharmacology analysis and molecular docking

RETRACTED ARTICLE: Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C4

Stability analysis of rainfall-induced landslide considering air resistance delay effect and lateral seepage

The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals

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