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Showing 1–8 of 8 results
Advanced filters: Author: Srigokul Upadhyayula Clear advanced filters

  • PetaKit5D offers versatile processing workflows for light sheet microscopy data including performant image input/output, geometric transformations, deconvolution and stitching. The software is efficient and scalable to petabyte-size datasets.

    • Xiongtao Ruan
    • Matthew Mueller
    • Srigokul Upadhyayula
    ResearchOpen Access
    Nature Methods
    Volume: 21, P: 2342-2352

  • PIEZO1 is critical in numerous physiological processes, but monitoring its activity and localization in cells can be challenging. Here, the authors present a chemogenetic platform to visualize endogenous human PIEZO1 localization and activity in native cellular conditions, expanding the knowledge on mechanotransduction across single cells and tissue organoids.

    • Gabriella A. Bertaccini
    • Ignasi Casanellas
    • Medha M. Pathak
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-18

  • A neural space–time model can recover a dynamic scene by modeling its spatiotemporal relationship in multi-shot imaging reconstruction for reduced motion artifacts and improved imaging of fast processes in living cells.

    • Ruiming Cao
    • Nikita S. Divekar
    • Laura Waller
    ResearchOpen Access
    Nature Methods
    Volume: 21, P: 2336-2341

  • Expansion microscopy, or ExM, physically expands biological specimens upon embedding them in swellable polymeric hydrogels, allowing nanoscale imaging using conventional microscopes. This work presents a diamond lattice polymeric hydrogel synthesized via click chemistry, which achieves higher homogeneity than the ones currently in use, allowing a more accurate sample expansion.

    • Ruixuan Gao
    • Chih-Chieh (Jay) Yu
    • Edward S. Boyden
    Research
    Nature Nanotechnology
    Volume: 16, P: 698-707