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Showing 1–3 of 3 results

Advanced filters: Author: Stéphanie Torrino Clear advanced filters

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

HACE1 is an E3 ligase that promotes degradation of the GTPase Rac1. Here Daugaard et al. show that HACE1 inhibits the activity of Rac1-dependent NADPH oxidase complexes, which reduces the production of cellular reactive oxygen species and cell cycle progression.

Mads Daugaard
Roberto Nitsch
Poul H. Sorensen
ResearchOpen Access17 Jul 2013
Nature Communications

Volume: 4, P: 1-13
GLS2 links glutamine metabolism and atherosclerosis by remodeling artery walls

Murcy et al. show that increasing the plasma glutamine-to-glutamate ratio in atherosclerosis can distally reprogram transcriptional and post-transcriptional remodeling of the aorta by GLS2-dependent hepatic glutaminolysis.

Florent Murcy
Coraline Borowczyk
Laurent Yvan-Charvet
Research19 Nov 2024
Nature Cardiovascular Research

Volume: 3, P: 1454-1467
EHD2 is a Predictive Biomarker of Chemotherapy Efficacy in Triple Negative Breast Carcinoma

Wei-Wei Shen
Ivan Bièche
Christophe Lamaze
ResearchOpen Access14 May 2020
Scientific Reports

Volume: 10, P: 1-12