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Showing 351–400 of 505 results

Advanced filters: Author: Stephen E. Robinson Clear advanced filters

The use of sonicated lipid vesicles for mass spectrometry of membrane protein complexes

Native mass spectrometry is a powerful technique for studying intact proteins and protein complexes. Using this protocol, meaningful structural information on protein complexes ejected from sonicated native membrane vesicles can be obtained.

Dror S. Chorev
Haiping Tang
Carol V. Robinson
Protocols01 Apr 2020
Nature Protocols

Volume: 15, P: 1690-1706
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

Colin Cooper and colleagues report genome-wide sequences of multiple samples of multifocal cancer and morphologically normal tissue from the prostates of three men. They found high levels of mutations in morphologically normal tissue distant from the cancer, consistent with field effects.

Colin S Cooper
Rosalind Eeles
David E Neal
Research02 Mar 2015
Nature Genetics

Volume: 47, P: 367-372
Monitoring clonal burden as an alternative to blast count for myelodysplastic neoplasm treatment response

Meagan A. Jacoby
Eric D. Duncavage
Matthew J. Walter
Research04 Oct 2024
Leukemia

Volume: 39, P: 166-177
Perovskite nickelates as electric-field sensors in salt water

Application of an electric field changes the transport and optical properties of samarium nickelate submerged in water, making it a suitable passive sensor of weak electric fields in salt water.

Zhen Zhang
Derek Schwanz
Shriram Ramanathan
Research18 Dec 2017
Nature

Volume: 553, P: 68-72
Long-Lasting Changes in Morphine-Induced Locomotor Sensitization and Tolerance in Long-Evans Mother Rats as a Result of Periodic Postpartum Separation from the Litter: A Novel Model of Increased Vulnerability to Drug Abuse?

Mikhail Kalinichev
Keith W Easterling
Stephen G Holtzman
Research20 Sept 2002
Neuropsychopharmacology

Volume: 28, P: 317-328
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

Kerstin Kläser
Erika Molteni
Emma L. Duncan
ResearchOpen Access28 Jun 2022
Scientific Reports

Volume: 12, P: 1-17
Mendelian randomisation study of smoking exposure in relation to breast cancer risk

Hanla A. Park
Sonja Neumeyer
Jenny Chang-Claude
ResearchOpen Access02 Aug 2021
British Journal of Cancer

Volume: 125, P: 1135-1145
Author Correction: Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance

Patrick Munk
Christian Brinch
Frank M. Aarestrup
Amendments and CorrectionsOpen Access12 Jan 2023
Nature Communications

Volume: 14, P: 1
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

An in vivo transposon screen in a pancreatic cancer model identifies frequent inactivation of Usp9x; deletion of Usp9x cooperates with Kras^G12D to accelerate rapidly pancreatic tumorigenesis in mice, validating their genetic interaction.

Pedro A. Pérez-Mancera
Alistair G. Rust
David A. Tuveson
Research29 Apr 2012
Nature

Volume: 486, P: 266-270
A model for harmonizing flow cytometry in clinical trials

Complexities in sample handling, instrument setup and data analysis are barriers to the effective use of flow cytometry to monitor immunological parameters in clinical trials. The novel use of a central laboratory may help mitigate these issues.

Holden T Maecker
J Philip McCoy Jr
Jung-Hua Yeh
Comments & Opinion19 Oct 2010
Nature Immunology

Volume: 11, P: 975-978
The power of ion mobility-mass spectrometry for structural characterization and the study of conformational dynamics

Ion mobility-mass spectrometry (IM-MS) is enhancing many areas of (bio)chemical analysis because it can separate ions both by their mass-to-charge ratio and differences in their cross-sectional area. IM-MS can be used for structural characterization, enhanced analysis of complex mixtures or to gain insights into conformational dynamics.

Francesco Lanucara
Stephen W. Holman
Claire E. Eyers
Reviews21 Mar 2014
Nature Chemistry

Volume: 6, P: 281-294
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers

Nichola Johnson
Sarah Maguire
Olivia Fletcher
ResearchOpen Access26 Jan 2021
British Journal of Cancer

Volume: 124, P: 842-854
Multiple newly identified loci associated with prostate cancer susceptibility

Rosalind A Eeles
Zsofia Kote-Jarai
Douglas F Easton
Research10 Feb 2008
Nature Genetics

Volume: 40, P: 316-321
Quantitative analysis of size and regional distribution of corpora amylacea in the hippocampal formation of obstructive sleep apnoea patients

Cuicui Xu
Jessica E. Owen
Stephen R. Robinson
ResearchOpen Access22 Oct 2021
Scientific Reports

Volume: 11, P: 1-14
Rising CO₂ enhances hypoxia tolerance in a marine fish

Daniel W. Montgomery
Stephen D. Simpson
Rod W. Wilson
ResearchOpen Access22 Oct 2019
Scientific Reports

Volume: 9, P: 1-10
Early Neonatal Experience of Long-Evans Rats Results in Long-lasting Changes in Reactivity to a Novel Environment and Morphine-induced Sensitization and Tolerance

Mikhail Kalinichev
Keith W Easterling
Stephen G Holtzman
Research01 Mar 2002
Neuropsychopharmacology

Volume: 27, P: 518-533
Comparative genomic analysis of thermophilic fungi reveals convergent evolutionary adaptations and gene losses

An extensive comparative genomic analysis of thermophilic, thermotolerant, and mesophilic fungi genomes is used to define features of thermophily and shows the power of integrating phylogenetic analysis with machine learning and AlphaFold2 to obtain insights into the evolutionary origins of a specific physiology.

Andrei S. Steindorff
Maria Victoria Aguilar-Pontes
Igor V. Grigoriev
ResearchOpen Access12 Sept 2024
Communications Biology

Volume: 7, P: 1-11
Coastal leatherback turtles reveal conservation hotspot

Nathan J. Robinson
Stephen J. Morreale
Frank V. Paladino
ResearchOpen Access25 Nov 2016
Scientific Reports

Volume: 6, P: 1-9
Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria

Fluorescent labelling is used to show that in E. coli, outer membrane protein (OMP) turnover is passive and binary in nature, and OMPs cluster to form islands in which diffusion of individual proteins is restricted owing to lateral interactions with other OMPs; new OMPs are inserted mostly at mid-cell, meaning that old OMP islands are displaced to the poles of growing cells.

Patrice Rassam
Nikki A. Copeland
Colin Kleanthous
Research10 Jun 2015
Nature

Volume: 523, P: 333-336
CCR2 mediates increased susceptibility to post-H1N1 bacterial pneumonia by limiting dendritic cell induction of IL-17

Stephen J. Gurczynski
Niket Nathani
Bethany B. Moore
Research29 Nov 2018
Mucosal Immunology

Volume: 12, P: 518-530
Genomic analyses of human adenoviruses unravel novel recombinant genotypes associated with severe infections in pediatric patients

Joyce Odeke Akello
Richard Kamgang
Alban Ramette
ResearchOpen Access15 Dec 2021
Scientific Reports

Volume: 11, P: 1-10
Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language

Ellen Verhoef
Ditte Demontis
Beate St Pourcain
ResearchOpen Access24 Jan 2019
Translational Psychiatry

Volume: 9, P: 1-12
Exome-wide study of ankylosing spondylitis demonstrates additional shared genetic background with inflammatory bowel disease

Philip C Robinson
Paul J Leo
Matthew A Brown
ResearchOpen Access04 May 2016
npj Genomic Medicine

Volume: 1, P: 1-6
Correction: Myeloablative conditioning for allo-HSCT in pediatric ALL: FTBI or chemotherapy?—A multicenter EBMT-PDWP study

Andre Manfred Willasch
Christina Peters
Peter Bader
Amendments and CorrectionsOpen Access19 Aug 2021
Bone Marrow Transplantation

Volume: 56, P: 2615
Association between nocturnal activity of the sympathetic nervous system and cognitive dysfunction in obstructive sleep apnoea

Ridwan M. Alomri
Gerard A. Kennedy
Stephen R. Robinson
ResearchOpen Access07 Jun 2021
Scientific Reports

Volume: 11, P: 1-11
Disruption prediction with artificial intelligence techniques in tokamak plasmas

Tokamak plasmas are prone to sudden collapses that terminate the nuclear fusion reactions. This perspective discusses the prediction of these so-called disruptions with artificial intelligence techniques.

J. Vega
A. Murari
I. Zychor
Reviews06 Jun 2022
Nature Physics

Volume: 18, P: 741-750
Genome of the endangered eastern quoll (Dasyurus viverrinus) reveals signatures of historical decline and pelage color evolution

Genome sequencing of the eastern quoll, an endangered marsupial, describes historical population declines and identifies the likely basis of its colour differences with the closely related Tasmanian devil.

Gabrielle A. Hartley
Stephen R. Frankenberg
Charles Y. Feigin
ResearchOpen Access25 May 2024
Communications Biology

Volume: 7, P: 1-8
Correction: Idelalisib exposure before allogeneic stem cell transplantation in patients with follicular lymphoma: an EBMT survey

Leopold Sellner
Johannes Schetelig
Peter Dreger
Amendments and CorrectionsOpen Access07 Oct 2021
Bone Marrow Transplantation

Volume: 56, P: 3108
The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Primary triple-negative breast cancers are shown to vary widely and continuously in the degree of clonal evolution and mutational content at the time of diagnosis, with implications for future studies of the disease.

Sohrab P. Shah
Andrew Roth
Samuel Aparicio
Research04 Apr 2012
Nature

Volume: 486, P: 395-399
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

Community microattribution review of the evidence for colon cancer risk conferred by constitutional variants in MLH1, MSH2, MSH6 and PMS2 has resulted in the reclassification of two-thirds of the variants reported in existing databases and led to clinical recommendations for the interpretation of 1,370 variants that do not result in obvious protein truncation.

Bryony A Thompson
Amanda B Spurdle
Victor-Manuel Barbera
Research22 Dec 2013
Nature Genetics

Volume: 46, P: 107-115
Conventional radical versus focal treatment for localised prostate cancer: a propensity score weighted comparison of 6-year tumour control

Marieke J. van Son
Max Peters
Alison Falconer
Research01 May 2021
Prostate Cancer and Prostatic Diseases

Volume: 24, P: 1120-1128
1179 MODULATION OF SOMATOMEDIN RECEPTOR SITES IN GROWTH HORMONE-TREATED HYPOPITUITARY DWARFS

Ron G Rosenfeld
Stephen F Kemp
Raymond L Hintz
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 639
Ancient plant DNA in the genomic era

Next-generation sequencing technologies have significantly changed the scope of ancient plant DNA research, moving from analysis of a few loci to generation of ancient genomes. Future research could refine our understanding of plant evolution and adaptation, and provide information for conservation, crop breeding and food security.

Oscar Estrada
James Breen
Alan Cooper
Comments & Opinion18 Jun 2018
Nature Plants

Volume: 4, P: 394-396
Post-transcriptional silencing of RET occurs, but is not required, during raf-1 mediated differentiation of medullary thyroid carcinoma cells

Eleanor B Carson-Walter
Darrin P Smith
Barry D Nelkin
Research28 Jul 1998
Oncogene

Volume: 17, P: 367-376
The mTORC1 complex in pre-osteoblasts regulates whole-body energy metabolism independently of osteocalcin

Pawanrat Tangseefa
Sally K. Martin
Andrew C. W. Zannettino
ResearchOpen Access08 Feb 2021
Bone Research

Volume: 9, P: 1-17
Interactions of Steroid, Methotrexate, and Radiation Determine Neurotoxicity in an Animal Model to Study Therapy for Childhood Leukemia

Phyllis J Mullenix
William J Kernan
Nancy J Tarbell
Research01 Feb 1994
Pediatric Research

Volume: 35, P: 171-178
Exploring the somatic NF1 mutational spectrum associated with NF1 cutaneous neurofibromas

Laura Thomas
Gill Spurlock
Meena Upadhyaya
Research23 Nov 2011
European Journal of Human Genetics

Volume: 20, P: 411-419
Amino Acid (System A) Transporter Activity in Microvillous Membrane Vesicles from the Placentas of Appropriate and Small for Gestational Age Babies

Dhushy Maiiendran
Paul Donnai
Colin P Sibley
Research01 Nov 1993
Pediatric Research

Volume: 34, P: 661-665
HDAC6 promotes growth, migration/invasion, and self-renewal of rhabdomyosarcoma

Thao Q. Pham
Kristin Robinson
Eleanor Y. Chen
Research16 Nov 2020
Oncogene

Volume: 40, P: 578-591
E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium

Hisani N. Horne
Hannah Oh
Jonine D. Figueroa
ResearchOpen Access26 Apr 2018
Scientific Reports

Volume: 8, P: 1-11
Author Correction: Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders

Tianyun Wang
Kendra Hoekzema
Evan E. Eichler
Amendments and CorrectionsOpen Access21 Oct 2020
Nature Communications

Volume: 11, P: 1
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli
Massimo Bogliolo
Paolo Peterlongo
ResearchOpen Access01 Nov 2019
npj Breast Cancer

Volume: 5, P: 1-14
Fusarium graminearum A 3/5 as a Novel Host for Heterologous Protein Production

John C. Royer
Donna L. Moyer
Jeffrey R. Shuster
Research01 Dec 1995
Bio/Technology

Volume: 13, P: 1479-1483
Mechanism and isotherm modeling of effective adsorption of malachite green as endocrine disruptive dye using Acid Functionalized Maize Cob (AFMC)

John O Ojediran
Adewumi Oluwasogo Dada
Adejoke D Adewumi
ResearchOpen Access02 Nov 2021
Scientific Reports

Volume: 11, P: 1-15
Comparative genomics of Mollicutes-related endobacteria supports a late invasion into Mucoromycota fungi

Probing the evolution of bacterial endosymbionts in Mucoromycota - Mollicutes-related endobacteria (MRE) - reveals that the genera Linnemannia and Benniella acquired MRE after host divergence from a common ancestor.

Reid Longley
Aaron Robinson
Gregory Bonito
ResearchOpen Access18 Sept 2023
Communications Biology

Volume: 6, P: 1-13
Mapping of population disparities in the cholangiocarcinoma urinary metabolome

Munirah Alsaleh
Zoe Leftley
Simon D. Taylor-Robinson
ResearchOpen Access28 Oct 2021
Scientific Reports

Volume: 11, P: 1-12
Myocardial Gene Expression Associated with Genetic Cardiac Hypertrophy in the Absence of Hypertension

Jeremy P Dwyer
Matthew E Ritchie
Robert Di Nicolantonio
Research01 May 2008
Hypertension Research

Volume: 31, P: 941-955
Multi-attenuated herpes simplex virus-1 mutant G207 exerts cytotoxicity against epithelial ovarian cancer but not normal mesothelium and is suitable for intraperitoneal oncolytic therapy

George Coukos
Antonis Makrigiannakis
Katherine L Molnar-Kimber
Research24 May 2000
Cancer Gene Therapy

Volume: 7, P: 275-283
Precision treatment of beta-cell monogenic diabetes: a systematic review

Naylor et al. systematically review the efficacy of treatments for beta-cell monogenic diabetes. Limited evidence from the mostly non-randomized, small studies supports no treatment in glucokinase-related hyperglycemia and sulfonylureas for HNF1A-diabetes; further evidence is needed on the optimum treatments in these and other monogenic subtypes.

Rochelle N. Naylor
Kashyap A. Patel
Tiinamaija Tuomi
ResearchOpen Access18 Jul 2024
Communications Medicine

Volume: 4, P: 1-17
Treosulfan compared to busulfan in allogeneic haematopoietic stem cell transplantation for myelofibrosis: a registry-based study from the Chronic Malignancies Working Party of the EBMT

Marie Robin
Simona Iacobelli
Donal P. McLornan
Research15 Mar 2024
Bone Marrow Transplantation

Volume: 59, P: 928-935

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