A tubular assembly based on barrel-shaped chaperonin protein mutants, held together through coordination to magnesium ions, has been devised that carries and delivers guests into cells. The hydrolysis of ATP — present in much higher concentration inside the cell than outside — induces a conformational change in chaperonin that in turn triggers the guest release.
- Shuvendu Biswas
- Kazushi Kinbara
- Takuzo Aida