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Showing 1–50 of 51 results

Advanced filters: Author: Susumu Harada Clear advanced filters

Host control of persistent Epstein–Barr virus infection

Axel Schmidt
T. Madhusankha Alawathurage
Kerstin U. Ludwig
Research19 Feb 2026
Nature

P: 1-5
Methylmercury and selenium in umbilical cords of inhabitants of the Minamata area

SUSUMU NISHIGAKI
MASAZUMI HARADA
Research27 Nov 1975
Nature

Volume: 258, P: 324-325
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

Toshio Hirano
Kiyoshi Yasukawa
Tadamitsu Kishimoto
Research06 Nov 1986
Nature

Volume: 324, P: 73-76
Influence of Cationic Polyelectrolytes on the Reaction of 5,5′-Dithiobis(2-nitrobenzoate) with Cyanide Ion

Toshio Ueda
Susumu Harada
Norio Ise
Research01 Jul 1974
Polymer Journal

Volume: 6, P: 326-328
Catalysis by Cationic Polyelectrolytes in Hydrolysis of Dinitrophenyl Phosphate Dianions

Toshio Ueda
Susumu Harada
Norio Ise
Research01 Jul 1972
Polymer Journal

Volume: 3, P: 476-481
Influence of Cationic Polyelectrolytes on the Reaction of Chloroacetate with Thiosulfate

Toshio Ueda
Susumu Harada
Norio Ise
Research01 Jul 1974
Polymer Journal

Volume: 6, P: 308-312
Influence of Cationic Polyelectrolytes on Reactions of 2,4-Dinitrofluorobenzene with Amino Acids and Peptides

Toshio Ueda
Susumu Harada
Norio Ise
Research01 Jul 1974
Polymer Journal

Volume: 6, P: 318-321
Syntheses of Cationic Polysoaps and Their Rate-Enhancing Effect

Toshio Ueda
Susumu Harada
Norio Ise
Research01 Nov 1974
Polymer Journal

Volume: 6, P: 473-479
Influence of Cationic Poly electrolytes in the Aromatic Nucleophilic Substitution Reaction of 3,5-Dinitro-4-chlorobenzoate

Toshio Ueda
Susumu Harada
Norio Ise
Research01 Jul 1974
Polymer Journal

Volume: 6, P: 313-317
Raman spectra of transfer RNAs with ultraviolet lasers

YOSHIFUMI NISHIMURA
AKIKO Y. HIRAKAWA
SUSUMU NISHIMURA
Research11 Mar 1976
Nature

Volume: 260, P: 173-174
Initiator tRNAs from archaebacteria show common unique sequence characteristics

Yoshiyuki Kuchino
Makoto Ihara
Susumu Nishimura
Research12 Aug 1982
Nature

Volume: 298, P: 684-685
Three-dimensional structure of hyper-modified nucleoside Q located in the wobbling position of tRNA

Shigeyuki Yokoyama
Tatsuo Miyazawa
Susumu Nishimura
Research01 Nov 1979
Nature

Volume: 282, P: 107-109
Structural differences between a ras oncogene protein and the normal protein

Liang Tong
Abraham M. de Vos
Sung-Hou kim
Research05 Jan 1989
Nature

Volume: 337, P: 90-93
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Genetic mechanisms influencing COVID-19 susceptibility are not well understood. Here, the authors analyzed whole blood RNA-seq data of 465 Japanese individuals with COVID-19, highlighting thousands of fine-mapped variants affecting expression and splicing of genes, as well as the presence of COVID-19 severity-interaction eQTLs.

Qingbo S. Wang
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-19
DOCK2 is involved in the host genetics and biology of severe COVID-19

A genome-wide association study highlights a variant in DOCK2, which is common in East Asian populations but rare in Europeans, as a host genetic risk factor for severe COVID-19.

Ho Namkoong
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access08 Aug 2022
Nature

Volume: 609, P: 754-760
Structural Characterization of Microcystins by LC/MS/MS under Ion Trap Conditions

Tsuyoshi Mayumi
Hajime Kato
Ken-ichi Harada
Research01 Nov 2006
The Journal of Antibiotics

Volume: 59, P: 710-719
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

A single-cell multiomic immune cell atlas from 235 Japanese, including patients with COVID-19 and healthy individuals, linked with host genetics including germline and somatic mutation, plasma proteomics and metagenomics data reveals that immune cells are dynamically regulated in a cell state-dependent manner.

Ryuya Edahiro
Go Sato
Yukinori Okada
ResearchOpen Access28 Jul 2025
Nature Genetics

Volume: 57, P: 1905-1921
Human–Human Hybridomas Secreting Hepatitis B Virus–Neutralizing Antibodies

Kaori Harada
Yuzo Ichimori
Yukio Sugino
Research01 Apr 1989
Bio/Technology

Volume: 7, P: 374-377
Codon and amino-acid specificities of a transfer RNA are both converted by a single post-transcriptional modification

Tomonari Muramatsu
Kazuya Nishikawa
Shigeyuki Yokoyama
Research10 Nov 1988
Nature

Volume: 336, P: 179-181
Blood DNA virome associates with autoimmune diseases and COVID-19

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Noah Sasa
Shohei Kojima
Yukinori Okada
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 65-79
Symposium at the 26th Annual Meeting of the Japan Society of Human Genetics, 1981: Genetic Markers in Blood Genetic markers

Susumu Shibata
Research01 Jun 1982
Japanese journal of human genetics

Volume: 27, P: 71-79
Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization

DNA hypomethylating agents (HMAs) are used for the treatment of myeloid malignancies, but their therapeutic effects are not satisfactory. Here, the authors show that inhibition of TOPORS, which encodes a ubiquitin E3 ligase, augments the efficacy of HMAs through DNMT1 stabilization.

Satoshi Kaito
Kazumasa Aoyama
Atsushi Iwama
ResearchOpen Access28 Aug 2024
Nature Communications

Volume: 15, P: 1-18
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Peripheral blood mononuclear cells from 73 Japanese patients with coronavirus disease 2019 (COVID-19) and 75 healthy controls were analyzed using single-cell transcriptomics. Combining these data with genotyping data highlights the interplay between host genetics and the immune response in modulating disease severity.

Ryuya Edahiro
Yuya Shirai
Yukinori Okada
ResearchOpen Access24 Apr 2023
Nature Genetics

Volume: 55, P: 753-767
Iron-complex-based catalytic system for high-performance water oxidation in aqueous media

While water oxidation is the key reaction in natural and artificial photosynthesis, it is kinetically and thermodynamically sluggish, so constructing a molecular system in aqueous media remains challenging. Here, the authors report highly efficient water oxidation in aqueous media via electrochemical polymerisation of a pentanuclear iron complex.

Takumi Matsuzaki
Kento Kosugi
Shigeyuki Masaoka
ResearchOpen Access05 Mar 2025
Nature Communications

Volume: 16, P: 1-11
IL-10 promotes Th17 cell differentiation by enhancing STAT1-dependent IL-6 production via IgE-stimulated mast cells

Takafumi Numata
Masashi Ikutani
Susumu Nakae
ResearchOpen Access04 Nov 2024
Scientific Reports

Volume: 14, P: 1-8
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes

Fujita et al. find that normal epithelial cells induce metabolic changes in adjacent transformed cells, causing their apical extrusion. The effect is conveyed non-cell-autonomously and relies on PDK4-mediated inhibition of mitochondrial function.

Shunsuke Kon
Kojiro Ishibashi
Yasuyuki Fujita
Research17 Apr 2017
Nature Cell Biology

Volume: 19, P: 530-541
A New Antibiotic, Antimycin A₉, Produced by Streptomyces sp. K01-0031

Kazuro Shiomi
Kenji Hatae
Satoshi Ōmura
Research01 Jan 2005
The Journal of Antibiotics

Volume: 58, P: 74-78
Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

PGRMC1 binds to EGFR and cytochromes P450, and is known to be involved in cancer proliferation and in drug resistance. Here, the authors determine the structure of the cytosolic domain of PGRMC1, which forms a dimer via haem–haem stacking, and propose how this interaction could be involved in its function.

Yasuaki Kabe
Takanori Nakane
Makoto Suematsu
ResearchOpen Access18 Mar 2016
Nature Communications

Volume: 7, P: 1-13
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Genetic studies of familial amyloid polyneuropathy in the Arao district of Japan

Masao Ueji
Tomokazu Suzuki
Akira Nakajima
Research01 Sept 1984
Japanese Journal of Human Genetics

Volume: 29, P: 311-325
Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Youngjune Bhak
Vasilis Raptis
Albert Tenesa
ResearchOpen Access28 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor

Tetsuya Ohtaki
Yasushi Shintani
Masahiko Fujino
Research31 May 2001
Nature

Volume: 411, P: 613-617
Low Frequency Regular Exercise Improves Flow-Mediated Dilatation of Subjects with Mild Hypertension

Jiro Moriguchi
Hiroshi Itoh
Susumu Sasaki
Research01 Apr 2005
Hypertension Research

Volume: 28, P: 315-321
The Study of Circular Dichroic Difference Spectra Applied to Polynucleotides and Ribonucleic Acids

Kimitsuna Watanabe
Takeshi Seno
Kazutomo Imahori
Research01 May 1973
Polymer Journal

Volume: 4, P: 539-552
Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016

Ai Kurogi
Daisuke Onozuka
Masayuki Yokota
ResearchOpen Access28 Feb 2022
Scientific Reports

Volume: 12, P: 1-17
Association of a polymorphism of the 5HT2A receptor gene promoter region with alcohol dependence

T Nakamura
S Matsushita
S Higuchi
Research22 Jan 1999
Molecular Psychiatry

Volume: 4, P: 85-88
Perinatal outcomes in RhD-negative pregnant women in Japan

Ken Takahashi
Susumu Yoshida
Osamu Samura
ResearchOpen Access22 Mar 2025
Scientific Reports

Volume: 15, P: 1-10
Sarcomere gene variants did not improve cardiac function in pediatric patients with dilated cardiomyopathy from Japanese cohorts

Keiichi Hirono
Yukiko Hata
Fukiko Ichida
ResearchOpen Access16 Dec 2024
Scientific Reports

Volume: 14, P: 1-14
Lectin histochemistry of posterior lingual glands of developing rats

Kazuma Harada
Koji Miki
Satoshi Wakisaka
ResearchOpen Access26 Jun 2023
Scientific Reports

Volume: 13, P: 1-11
Correction: Distribution and survival strategies of endemic and cosmopolitan diazotrophs in the Arctic Ocean

Takuhei Shiozaki
Yosuke Nishimura
Naomi Harada
Amendments and CorrectionsOpen Access01 Jun 2023
The ISME Journal

Volume: 17, P: 1351
Nucleation and polymorphism of trans-1,4-polyisoprene containing copper phthalocyanine

Effect of α- or β-Copper phthalocyanine (CuPc) as a nucleating agent through crystallization of trans-1,4-polyisoprene (TPI) was evaluated. Observation by polarized optical microscopy showed that the low-melting crystal form is generated at the interface between TPI and either of α- or β-CuPc selectively when crystallized at 38 °C. In differential scanning calorimetry measurements, TPI composites containing α- or β-CuPc showed higher crystallization temperature than that of pure TPI during the cooling process from the melt.

Tomoya Tsuboi
Masashi Harada
Takashi Itoh
Research06 Feb 2013
Polymer Journal

Volume: 45, P: 915-920
Bone microstructural characteristics or positional changes of condyle head affect short-term condyle head resorption after orthognathic surgery

Kazuaki Miyagawa
Chihiro Arikawa
Emiko Tanaka Isomura
ResearchOpen Access20 Jun 2024
Scientific Reports

Volume: 14, P: 1-14
NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population

Nao Nishida
Yoshihiro Aiba
Minoru Nakamura
ResearchOpen Access23 May 2018
Scientific Reports

Volume: 8, P: 1-9
Distribution and survival strategies of endemic and cosmopolitan diazotrophs in the Arctic Ocean

Takuhei Shiozaki
Yosuke Nishimura
Naomi Harada
ResearchOpen Access23 May 2023
The ISME Journal

Volume: 17, P: 1340-1350
Efficient and accurate KRAS genotyping using digital PCR combined with melting curve analysis for ctDNA from pancreatic cancer patients

Junko Tanaka
Tatsuo Nakagawa
Chihiro Uematsu
ResearchOpen Access21 Feb 2023
Scientific Reports

Volume: 13, P: 1-10
Increased abundance of Ruminococcus gnavus in gut microbiota is associated with moyamoya disease and non-moyamoya intracranial large artery disease

Yohei Mineharu
Yasuhisa Nakamura
Kouji H. Harada
ResearchOpen Access24 Nov 2022
Scientific Reports

Volume: 12, P: 1-15
Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis

Yoshihiro Aiba
Kenichi Harada
Minoru Nakamura
ResearchOpen Access07 Aug 2018
Scientific Reports

Volume: 8, P: 1-11
Dysregulation of RNF213 promotes cerebral hypoperfusion

Takaaki Morimoto
Jun-ichiro Enmi
Akio Koizumi
ResearchOpen Access26 Feb 2018
Scientific Reports

Volume: 8, P: 1-9
Structural basis for PPARγ transactivation by endocrine-disrupting organotin compounds

Shusaku Harada
Youhei Hiromori
Tsuyoshi Nakanishi
ResearchOpen Access17 Feb 2015
Scientific Reports

Volume: 5, P: 1-7

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