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Showing 1–50 of 91 results

Advanced filters: Author: Susumu Watanabe Clear advanced filters

TMEPAI, a transmembrane TGF-β-inducible protein, sequesters Smad proteins in TGF-β signaling

Susumu Itoh
Yukihide Watanabe
Mitsuyasu Kato
ResearchOpen Access07 Dec 2007
Nature Precedings

P: 1
Thermotropic Liquid Crystals of Main-Chain Polyesters with a Mesogenic 4,4′-Biphenyldicarboxylate Unit XII. Unusual Molecular Orientation in Fibers Drawn from Smectic Melt

Masatoshi Tokita
Kensuke Osada
Junji Watanabe
Research01 Aug 1998
Polymer Journal

Volume: 30, P: 687-690
Distinct Temperature Dependence of Cholesteric Pitch in Lyotropic Cholesteric Solutions of Polypeptide

Hiroshi Kosho
Yasuyuki Tanaka
Junji Watanabe
Research01 Feb 1999
Polymer Journal

Volume: 31, P: 199-202
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

A single-cell multiomic immune cell atlas from 235 Japanese, including patients with COVID-19 and healthy individuals, linked with host genetics including germline and somatic mutation, plasma proteomics and metagenomics data reveals that immune cells are dynamically regulated in a cell state-dependent manner.

Ryuya Edahiro
Go Sato
Yukinori Okada
ResearchOpen Access28 Jul 2025
Nature Genetics

Volume: 57, P: 1905-1921
Raman spectra of transfer RNAs with ultraviolet lasers

YOSHIFUMI NISHIMURA
AKIKO Y. HIRAKAWA
SUSUMU NISHIMURA
Research11 Mar 1976
Nature

Volume: 260, P: 173-174
Infrared Spectrum of an Anticodon Fragment of a Transfer RNA

KOSUKE MORIKAWA
MASAMICHI TSUBOI
SUSUMU NISHIMURA
Research02 Aug 1969
Nature

Volume: 223, P: 537-538
Initiator tRNAs from archaebacteria show common unique sequence characteristics

Yoshiyuki Kuchino
Makoto Ihara
Susumu Nishimura
Research12 Aug 1982
Nature

Volume: 298, P: 684-685
Fission Track Dating of Archaeological Materials from Japan

SUSUMU NISHIMURA
Research26 Mar 1971
Nature

Volume: 230, P: 242-243
Conformational Analysis by IR and Birefringence Measurements for Poly(β-phenylpropyl L-aspartate) Exhibiting a Helical Sense Inversion in the Solid State

Koichi Sakajiri
Satoshi Saeki
Junji Watanabe
Research01 Sept 2000
Polymer Journal

Volume: 32, P: 803-806
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

Toshio Hirano
Kiyoshi Yasukawa
Tadamitsu Kishimoto
Research06 Nov 1986
Nature

Volume: 324, P: 73-76
Complete sequencing and characterization of 21,243 full-length human cDNAs

Toshio Ota
Yutaka Suzuki
Sumio Sugano
Research21 Dec 2003
Nature Genetics

Volume: 36, P: 40-45
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Genetic mechanisms influencing COVID-19 susceptibility are not well understood. Here, the authors analyzed whole blood RNA-seq data of 465 Japanese individuals with COVID-19, highlighting thousands of fine-mapped variants affecting expression and splicing of genes, as well as the presence of COVID-19 severity-interaction eQTLs.

Qingbo S. Wang
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-19
Blood DNA virome associates with autoimmune diseases and COVID-19

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Noah Sasa
Shohei Kojima
Yukinori Okada
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 65-79
DOCK2 is involved in the host genetics and biology of severe COVID-19

A genome-wide association study highlights a variant in DOCK2, which is common in East Asian populations but rare in Europeans, as a host genetic risk factor for severe COVID-19.

Ho Namkoong
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access08 Aug 2022
Nature

Volume: 609, P: 754-760
Scanning tunnelling spectroscopy of superconductivity on surfaces of LiTi₂O₄(111) thin films

Atomic and electronic reconstructions at surfaces/interfaces bring about various emergent phenomena. Here, Okadaet al. report an unexpected superconducting gap and a long coherence length on the surface of LiTi₂O₄(111) thin films.

Yoshinori Okada
Yasunobu Ando
Taro Hitosugi
ResearchOpen Access03 Jul 2017
Nature Communications

Volume: 8, P: 1-7
Watt-class high-power, high-beam-quality photonic-crystal lasers

Researchers demonstrate a watt-class high-power, single-mode photonic-crystal laser operating continuously at room temperature. A beam quality of M² ≤ 1.1 is achieved.

Kazuyoshi Hirose
Yong Liang
Susumu Noda
Research13 Apr 2014
Nature Photonics

Volume: 8, P: 406-411
Codon and amino-acid specificities of a transfer RNA are both converted by a single post-transcriptional modification

Tomonari Muramatsu
Kazuya Nishikawa
Shigeyuki Yokoyama
Research10 Nov 1988
Nature

Volume: 336, P: 179-181
Intestinal intraepithelial lymphocytes are a distinct set of γδ T cells

Marc Bonneville
Charles A. Janeway Jr
Susumu Tonegawa
Research01 Dec 1988
Nature

Volume: 336, P: 479-481
Publisher Correction: Dynamic structural states of ClpB involved in its disaggregation function

Takayuki Uchihashi
Yo-hei Watanabe
Toshio Ando
Amendments and CorrectionsOpen Access12 Jul 2019
Nature Communications

Volume: 10, P: 1
Plasma Immunoreactive Endothelin-1 Concentration in Human Fetal Blood: Its Relation to Asphyxia

Yuka Isozaki-Fukuda
Takatsugu Kojima
Yohnosuke Kobayashi
Research01 Sept 1991
Pediatric Research

Volume: 30, P: 244-247
The Study of Circular Dichroic Difference Spectra Applied to Polynucleotides and Ribonucleic Acids

Kimitsuna Watanabe
Takeshi Seno
Kazutomo Imahori
Research01 May 1973
Polymer Journal

Volume: 4, P: 539-552
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Dynamic structural states of ClpB involved in its disaggregation function

The bacterial protein disaggregation machine ClpB uses ATP to generate mechanical force to unfold and thread its protein substrates. Here authors visualize the ClpB ring using high-speed atomic force microscopy and capture conformational changes of the hexameric ring during the ATPase reaction.

Takayuki Uchihashi
Yo-hei Watanabe
Toshio Ando
ResearchOpen Access01 Jun 2018
Nature Communications

Volume: 9, P: 1-12
Gapped nodal planes and large topological Nernst effect in the chiral lattice antiferromagnet CoNb₃S₆

The antiferromagnet CoNb₃S₆ with chiral crystal lattice has near-zero magnetization, but exhibits a large thermoelectric Nernst effect in zero magnetic field, attributed to topological nodal planes in its electronic structure and magnetic spin-space group symmetries in the ordered state.

Nguyen Duy Khanh
Susumu Minami
Max Hirschberger
ResearchOpen Access26 Mar 2025
Nature Communications

Volume: 16, P: 1-10
Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling

Fetal cell ablation models are essential for congenital disease modeling and organ regeneration. Here, the authors develop a rodent inducible caspase 9 model that enables rapid, specific, and efficient cell ablation, characterize its features, and apply it to generate a novel kidney disease model.

Kenji Matsui
Masahito Watanabe
Shuichiro Yamanaka
ResearchOpen Access15 Mar 2025
Nature Communications

Volume: 16, P: 1-18
Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1

Takashi Miki
Masashi Suzuki
Susumu Seino
Research01 May 2002
Nature Medicine

Volume: 8, P: 466-472
Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Youngjune Bhak
Vasilis Raptis
Albert Tenesa
ResearchOpen Access28 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
Blood pressure during long-term cilostazol-based dual antiplatelet therapy after stroke: a post hoc analysis of the CSPS.com trial

Kazunori Toyoda
Masatoshi Koga
Hiroaki Tanaka
ResearchOpen Access09 Jul 2024
Hypertension Research

Volume: 47, P: 2238-2249
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Peripheral blood mononuclear cells from 73 Japanese patients with coronavirus disease 2019 (COVID-19) and 75 healthy controls were analyzed using single-cell transcriptomics. Combining these data with genotyping data highlights the interplay between host genetics and the immune response in modulating disease severity.

Ryuya Edahiro
Yuya Shirai
Yukinori Okada
ResearchOpen Access24 Apr 2023
Nature Genetics

Volume: 55, P: 753-767
Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling

Targetting tumour angiogenesis is a useful strategy to reduce tumour burden; however, the clinical benefits of anti-angiogenetic drugs are modest. Here, the authors show that HGFR signalling, which contributes to tumour angiogenesis, requires Arf6 and that blocking Arf6 can lead to reduced tumour growth in mice.

Tsunaki Hongu
Yuji Funakoshi
Yasunori Kanaho
Research04 Aug 2015
Nature Communications

Volume: 6, P: 1-12
Author Correction: Condensin association with histone H2A shapes mitotic chromosomes

Kenji Tada
Hiroaki Susumu
Yoshinori Watanabe
Amendments and Corrections01 Oct 2018
Nature

Volume: 563, P: E20
Structure-activity Relationships of Neoechinulin A Analogues with Cytoprotection against Peroxynitrite-induced PC12 Cell Death

Kuniaki Kimoto
Toshiaki Aoki
Takao Arai
Research01 Oct 2007
The Journal of Antibiotics

Volume: 60, P: 614-621
Neoechinulin A Protects PC12 Cells against MPP⁺-induced Cytotoxicity

Yoshihito Kajimura
Toshiaki Aoki
Takao Arai
Correspondence01 May 2008
The Journal of Antibiotics

Volume: 61, P: 330-333
Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016

Ai Kurogi
Daisuke Onozuka
Masayuki Yokota
ResearchOpen Access28 Feb 2022
Scientific Reports

Volume: 12, P: 1-17
Bialaphos Treatment of Transgenic Rice Plants Expressing a bar Gene Prevents Infection by the Sheath Blight Pathogen (Rhizoctonia solani)

Hirofumi Uchimiya
Michiaki Iwata
Seiichi Toki
Research01 Jul 1993
Bio/Technology

Volume: 11, P: 835-836
A Novel Nuclear Export Inhibitor JBIR-02, a New Piericidin Discovered from Streptomyces sp. ML55

Jun-ya Ueda
Takushi Togashi
Kazuo Shin-ya
Research01 Jul 2007
The Journal of Antibiotics

Volume: 60, P: 459-462
Hydride-based antiperovskites with soft anionic sublattices as fast alkali ionic conductors

Oxide-based lithium/sodium-rich antiperovskites are regarded as promising solid electrolytes. Here, authors report a series of antiperovskites with a soft lattice containing hydride (H^–) and chalcogenide (S^2–, Se^2–, Te^2–) anions, enabling the fast Li⁺ /Na⁺ transport assisted by rotational phonon modes.

Shenghan Gao
Thibault Broux
Hiroshi Kageyama
ResearchOpen Access08 Jan 2021
Nature Communications

Volume: 12, P: 1-10
The CLIP1–LTK fusion is an oncogenic driver in non‐small‐cell lung cancer

Whole-transcriptome sequencing of a subset of 75 non-small-cell lung cancer specimens in a multi-institutional genome screening study identified a fusion of the CLIP1 and LTK genes with transformational potential due to constitutive LTK kinase activity.

Hiroki Izumi
Shingo Matsumoto
Koichi Goto
Research24 Nov 2021
Nature

Volume: 600, P: 319-323
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Chondroitin sulphate N-acetylgalactosaminyl-transferase-1 inhibits recovery from neural injury

The glycosaminoglycan chondroitin sulphate inhibits axon growth. Here the authors show that mice deficient in chondroitin sulphate biosynthesis have increased levels of heparan sulphate, which is more efficient than chondroitinase in supporting recovery from spinal cord injury.

Kosei Takeuchi
Nozomu Yoshioka
Michihiro Igarashi
ResearchOpen Access12 Nov 2013
Nature Communications

Volume: 4, P: 1-11
Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor

Tetsuya Ohtaki
Yasushi Shintani
Masahiko Fujino
Research31 May 2001
Nature

Volume: 411, P: 613-617
Condensin association with histone H2A shapes mitotic chromosomes

Kenji Tada
Hiroaki Susumu
Yoshinori Watanabe
Research01 Jun 2011
Nature

Volume: 474, P: 477-483
Experimental gene therapy against subcutaneously implanted glioma with a herpes simplex virus-defective vector expressing interferon-γ

Hiroshi Kanno
Satoshi Hattori
Micheal G Kaplitt
Research22 Oct 1999
Cancer Gene Therapy

Volume: 6, P: 147-155
Structural Characterization of Microcystins by LC/MS/MS under Ion Trap Conditions

Tsuyoshi Mayumi
Hajime Kato
Ken-ichi Harada
Research01 Nov 2006
The Journal of Antibiotics

Volume: 59, P: 710-719
Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia

The molecular heterogeneity of KMT2A-rearranged infant acute lymphoblastic leukemia (ALL) remains poorly characterised. Here, the authors perform multi-omics analysis for 84 ALL patients and suggest 5 distinct subgroups for risk stratification and personalised treatment.’

Tomoya Isobe
Masatoshi Takagi
Junko Takita
ResearchOpen Access30 Aug 2022
Nature Communications

Volume: 13, P: 1-16
Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors

Leukemic stem cells (LSCs) in chronic myeloid leukemia are resistant to imatinib and therefore are a cause of relapse. The authors show that IRAK1/4-NF-κB-PD-L1 signaling is critical to mediate imatinib resistance in LSCs and that combining imatinib with blocking this signalling pathway can eliminate LSCs.

Yosuke Tanaka
Reina Takeda
Toshio Kitamura
ResearchOpen Access12 Jan 2022
Nature Communications

Volume: 13, P: 1-13
A New Antibiotic, Antimycin A₉, Produced by Streptomyces sp. K01-0031

Kazuro Shiomi
Kenji Hatae
Satoshi Ōmura
Research01 Jan 2005
The Journal of Antibiotics

Volume: 58, P: 74-78
Distinct functions of kainate receptors in the brain are determined by the auxiliary subunit Neto1

Of the three major types of ionotropic glutamate receptors, synaptic kainite receptors have slow channel kinetics. This study characterizes Neto1, a novel auxiliary subunit of kainite receptor that directly modulates ligand binding and slow kinetics of kainite receptors.

Christoph Straub
David L Hunt
Susumu Tomita
Research29 May 2011
Nature Neuroscience

Volume: 14, P: 866-873
Unveiling thermal transitions of polymers in subnanometre pores

Understanding the thermal transitions of confined polymers is important for the design of molecular scale devices. In this study, unusual thermal transitions are observed in polyethylene glycol chains incorporated in nanochannels of porous coordination polymers.

Takashi Uemura
Nobuhiro Yanai
Susumu Kitagawa
ResearchOpen Access05 Oct 2010
Nature Communications

Volume: 1, P: 1-8
Combination Therapy with Renin-Angiotensin System Inhibitors and the Calcium Channel Blocker Azelnidipine Decreases Plasma Inflammatory Markers and Urinary Oxidative Stress Markers in Patients with Diabetic Nephropathy

Susumu Ogawa
Takefumi Mori
Sadayoshi Ito
Research01 Jun 2008
Hypertension Research

Volume: 31, P: 1147-1155

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