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Showing 1–3 of 3 results
Advanced filters: Author: Swapnil Subhash Bawage Clear advanced filters

  • Here the authors present cyclic peptide-based AND-gated nanosensors to detect concomitant protease activity. These nanosensors improve detection specificity during immune checkpoint blockade therapy compared with off-tumour anti-viral immunity in a mouse model.

    • Anirudh Sivakumar
    • Hathaichanok Phuengkham
    • Gabriel A. Kwong
    Research
    Nature Nanotechnology
    Volume: 20, P: 441-450

  • Engineered neutralizing antibodies are potential therapeutics for numerous viruses, such as respiratory syncytial virus (RSV). Here, the authors develop an mRNA-based approach to express membrane-anchored neutralizing antibodies in the lung and demonstrate that it inhibits RSV infections in mice.

    • Pooja Munnilal Tiwari
    • Daryll Vanover
    • Philip J. Santangelo
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15