In this Review, Dinglasan and colleagues explore innovations that facilitate rapid microbial secondary metabolite discovery, focusing on recent techniques for the prediction of biosynthetic gene clusters (BGCs) from genomic data bases, isolating novel BGCs from the environment, and producing and detecting the chemical products of these sequences in the laboratory.
- Jaime Lorenzo N. Dinglasan
- Hiroshi Otani
- Nigel J. Mouncey