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Showing 1–50 of 96 results

Advanced filters: Author: T Sekine Clear advanced filters

High-pressure transformation of eclogite to garnetite in subducted oceanic crust

T. Sekine
T. Irifune
W. O. Hibberson
Research13 Feb 1986
Nature

Volume: 319, P: 584-586
Osmium evidence for synchronicity between a rise in atmospheric oxygen and Palaeoproterozoic deglaciation

The Early Palaeoproterozoic saw glaciations and a rise in atmospheric oxygen, but the link between these two changes is poorly understood. Here, osmium isotope records from sedimentary rocks indicate synchronicity between an episode of increasing oxygen and a glacial transition.

Yasuhito Sekine
Katsuhiko Suzuki
Teruyuki Maruoka
Research11 Oct 2011
Nature Communications

Volume: 2, P: 1-6
STAP-2 interacts with and modulates BCR-ABL-mediated tumorigenesis

Y Sekine
O Ikeda
T Matsuda
Research09 Jan 2012
Oncogene

Volume: 31, P: 4384-4396
Catalog of 434 single-nucleotide polymorphisms (SNPs) in genes of the alcohol dehydrogenase, glutathione S-transferase, and nicotinamide adenine dinucleotide, reduced (NADH) ubiquinone oxidoreductase families

A. Iida
S. Saito
Y. Nakamura
Research01 Jun 2001
Journal of Human Genetics

Volume: 46, P: 385-407
Heliconical smectic phases formed by achiral molecules

Systems that form chiral structures from achiral molecules are not common. Here, the authors synthesise a compound consisting of asymmetric and achiral bent-shaped mesogens, which exhibit a variety of liquid crystal phases including one in which chiral structures form from achiral constituent molecules.

Jordan P. Abberley
Ross Killah
Damian Pociecha
ResearchOpen Access15 Jan 2018
Nature Communications

Volume: 9, P: 1-7
Broad and strong memory CD4⁺ and CD8⁺ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

Questions have arisen as to whether patients with severe COVID-19 disease can generate a T cell response against SARS-CoV-2. Tao Dong and colleagues report that convalescent patients with COVID-19 harbor functional memory CD4⁺ and CD8⁺ T cells that recognize multiple epitopes that span the viral proteome. CD4⁺ T cells predominated the memory response in patients with severe disease, whereas higher proportions of CD8⁺ T cells were found in patients with mild disease.

Yanchun Peng
Alexander J. Mentzer
Tao Dong
Research04 Sept 2020
Nature Immunology

Volume: 21, P: 1336-1345
DUSP22/LMW-DSP2 regulates estrogen receptor-α-mediated signaling through dephosphorylation of Ser-118

Y Sekine
O Ikeda
T Matsuda
Research26 Mar 2007
Oncogene

Volume: 26, P: 6038-6049
Magnetic susceptibility stratigraphy of Pacific Pleistocene sediments

B. L. K. SOMAYAJULU
T. J. WALSH
C. RADHAKRISHNAMURTY
Research01 Feb 1975
Nature

Volume: 253, P: 616-617
Randomised phase II trial of irinotecan plus cisplatin vs irinotecan, cisplatin plus etoposide repeated every 3 weeks in patients with extensive-disease small-cell lung cancer

I Sekine
H Nokihara
T Tamura
ResearchOpen Access05 Feb 2008
British Journal of Cancer

Volume: 98, P: 693-696
Phase II study of high-dose dexamethasone-based association in acute and delayed high-dose cisplatin-induced emesis – JCOG study 9413

I Sekine
Y Nishiwaki
T Kodama
Research01 Jul 1997
British Journal of Cancer

Volume: 76, P: 90-92
Doping of C₆₀ with iodine

T. R. OHNO
G. H. KROLL
R. E. SMALLEY
Research30 Jan 1992
Nature

Volume: 355, P: 401
Targeting prohibitins activates the ISR through DELE1-HRI by impairing protein import into the mitochondrial matrix

Ismael Sánchez-Vera
Ana M. Cosialls
Joan Gil
Research25 Nov 2025
Cell Death & Differentiation

P: 1-15
Phase I study of cisplatin analogue nedaplatin (254-S) and paclitaxel in patients with unresectable squamous cell carcinoma

I Sekine
H Nokihara
N Saijo
ResearchOpen Access02 Mar 2004
British Journal of Cancer

Volume: 90, P: 1125-1128
Physical and functional interactions between STAT3 and KAP1

R Tsuruma
N Ohbayashi
T Matsuda
Research26 Nov 2007
Oncogene

Volume: 27, P: 3054-3059
Aeromagnetic anomalies and tectonic trends in and around the Benue Trough, Nigeria

D. E. Ajakaiye
D. H. Hall
S. B. Ojo
Research13 Feb 1986
Nature

Volume: 319, P: 582-584
An integrated single cell and spatial transcriptomic map of human white adipose tissue

Single-cell studies of human white adipose tissue (WAT) provide insights into the specialized cell types in the tissue. Here the authors combine publicly available and newly generated high-resolution and bulk transcriptomic results from multiple human datasets to provide a comprehensive cellular map of white adipose tissue.

Lucas Massier
Jutta Jalkanen
Niklas Mejhert
ResearchOpen Access15 Mar 2023
Nature Communications

Volume: 14, P: 1-19
Serum levels and biochemical characteristics of human ovarian carcinoma-associated antigen defined by murine monoclonal antibody, CF511

K Ohkawa
Y Tsukada
K Mitani
Research01 Dec 1989
British Journal of Cancer

Volume: 60, P: 953-960
Erratum: A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

Y Kochi
R Yamada
K Yamamoto
Amendments and Corrections01 Jun 2005
Nature Genetics

Volume: 37, P: 652
Wnt-deficient and hypoxic environment orchestrates squamous reprogramming of human pancreatic ductal adenocarcinoma

Tamagawa, Fujii et al. demonstrate that squamous differentiation in human pancreatic cancer can be attributed to TP63-mediated lineage conversion and epigenetic reprogramming that depends upon a hypoxic and Wnt-defective niche.

Hiroki Tamagawa
Masayuki Fujii
Toshiro Sato
Research04 Sept 2024
Nature Cell Biology

Volume: 26, P: 1759-1772
Searching potential energy surfaces by simulated annealing

L. T. Wille
Amendments and Corrections22 Jan 1987
Nature

Volume: 325, P: 374
Catalog of 320 single nucleotide polymorphisms (SNPs) in 20 quinone oxidoreductase and sulfotransferase genes

A. Iida
A. Sekine
Y. Nakamura
Research01 Apr 2001
Journal of Human Genetics

Volume: 46, P: 225-240
Erratum: Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction

K Ozaki
Y Ohnishi
T Tanaka
Amendments and Corrections01 Jan 2003
Nature Genetics

Volume: 33, P: 107
An evaporite sequence from ancient brine recorded in Bennu samples

Samples from the asteroid (101955) Bennu, returned by the OSIRIS-REx mission, include sodium-bearing phosphates and sodium-rich carbonates, sulfates, chlorides and fluorides formed during evaporation of a late-stage brine.

T. J. McCoy
S. S. Russell
D. S. Lauretta
ResearchOpen Access29 Jan 2025
Nature

Volume: 637, P: 1072-1077
Cell cycle arrest and apoptosis of leukemia cells induced by L-asparaginase

T Ueno
K Ohtawa
H Nishimura
Research01 Nov 1997
Leukemia

Volume: 11, P: 1858-1861
Functional lacrimal gland regeneration by transplantation of a bioengineered organ germ

Lacrimal glands maintain a healthy corneal epithelium but are dysfunctional for example in dry-eye disease. Here, the authors transplant bioengineered lacrimal and harderian gland germs into mice, where they connect to the host duct and nervous system and restore lacrimal gland function.

Masatoshi Hirayama
Miho Ogawa
Takashi Tsuji
ResearchOpen Access01 Oct 2013
Nature Communications

Volume: 4, P: 1-10
Nonvolatile optical phase shift in ferroelectric hafnium zirconium oxide

The authors present nonvolatile optical phase shift induced by ferroelectric hafnium zirconium oxide deposited on a SiN waveguide. This finding paves the way for largescale programmable photonic circuits for communication, computing, and sensing.

Kazuma Taki
Naoki Sekine
Mitsuru Takenaka
ResearchOpen Access09 May 2024
Nature Communications

Volume: 15, P: 1-8
Functional salivary gland regeneration by transplantation of a bioengineered organ germ

Salivary gland dysfunction as a result of diseases or ageing reduces the quality of life and causes various oral health problems. Here the authors show that the salivary gland function of mice can be recovered by orthotopic transplantation of a bioengineered salivary gland germ.

Miho Ogawa
Masamitsu Oshima
Takashi Tsuji
ResearchOpen Access01 Oct 2013
Nature Communications

Volume: 4, P: 1-10
Elevated CA125 levels in patients with metastatic breast carcinoma

L Perey
DF Hayes
S Leyvraz
Research01 Oct 1990
British Journal of Cancer

Volume: 62, P: 668-670
The future lifespan of Earth’s oxygenated atmosphere

Earth’s oxygen-rich atmosphere will probably persist for only one billion more years before it sharply deoxygenates to low-level oxygen similar to those of the Archaean, according to a combined biogeochemistry and climate model.

Kazumi Ozaki
Christopher T. Reinhard
Research01 Mar 2021
Nature Geoscience

Volume: 14, P: 138-142
Incomplete oxidative sulfide weathering and low atmospheric oxygen levels during the Great Oxidation Event

Limited oxidative weathering of crustal sulfide before the Gowganda glaciation suggests low atmospheric oxygen levels persisted long before the final Huronian glaciation, according to a geochemical and isotopic analysis of the upper Espanola and Serpent formations in Canada.

Kosuke T. Goto
Yasuhito Sekine
Eiichi Tajika
ResearchOpen Access17 Nov 2025
Communications Earth & Environment

Volume: 6, P: 1-11
Identification of 197 genetic variations in six human methyltransferase genes in the Japanese population

S. Saito
A. Iida
Y. Nakamura
Research01 Sept 2001
Journal of Human Genetics

Volume: 46, P: 529-537
Regulation of STAT3-mediated signaling by LMW-DSP2

Y Sekine
S Tsuji
T Matsuda
Research24 Apr 2006
Oncogene

Volume: 25, P: 5801-5806
Quantum Hall effect in epitaxial graphene with permanent magnets

F. D. Parmentier
T. Cazimajou
P. Roulleau
ResearchOpen Access06 Dec 2016
Scientific Reports

Volume: 6, P: 1-5
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Specificity analysis of sera from breast cancer patients vaccinated with MUC1-KLH plus QS-21

S Adluri
T Gilewski
P Livingston
ResearchOpen Access12 Mar 1999
British Journal of Cancer

Volume: 79, P: 1806-1812
Comparison of prognostic factors in patients in phase I trials of cytotoxic drugs vs new noncytotoxic agents

C Han
J P Braybrooke
D C Talbot
ResearchOpen Access30 Sept 2003
British Journal of Cancer

Volume: 89, P: 1166-1171
Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues

The authors provide a brief overview of the physiological and pharmacological relevance of proteins that translocate organic anions. Focusing on OATs located in the basolateral membrane of proximal tubule cells, the authors discuss data fromXenopusoocytes and knockout mice. The potential for new findings to shed light on an individual patient's response to treatment with a particular drug, and the risks of toxic effects, are emphasized.

Sanjay K Nigam
Kevin T Bush
Vibha Bhatnagar
Reviews01 Aug 2007
Nature Clinical Practice Nephrology

Volume: 3, P: 443-448
A second generation human haplotype map of over 3.1 million SNPs

A consortium reports the tripling of the number of genetic markers in Phase II of the International HapMap Project. This map of human genetic variation will continue to revolutionize discovery of susceptibility loci in common genetic diseases, and study of genes under selection in humans.

Kelly A. Frazer (Principal Investigator)
Dennis G. Ballinger
John Stewart
Research18 Oct 2007
Nature

Volume: 449, P: 851-861
Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia

T Iwai
S Yokota
T Fujimoto
Research27 Jan 1999
Leukemia

Volume: 13, P: 38-43
Phase II study of nedaplatin and irinotecan with concurrent thoracic radiotherapy in patients with locally advanced non-small-cell lung cancer

F Oshita
M Ohe
K Yamada
ResearchOpen Access12 Oct 2010
British Journal of Cancer

Volume: 103, P: 1325-1330
Multi-institutional phase II trial of irinotecan, cisplatin, and etoposide for sensitive relapsed small-cell lung cancer

K Goto
I Sekine
N Saijo
ResearchOpen Access27 Jul 2004
British Journal of Cancer

Volume: 91, P: 659-665
Clinical variant of Tangier disease in Japan: mutation of the ABCA1 gene in hypoalphalipoproteinemia with corneal lipidosis

J. Ishii
M. Nagano
M. Emi
Research01 Jul 2002
Journal of Human Genetics

Volume: 47, P: 366-369
Electrically driven single-electron spin resonance in a slanting Zeeman field

The integration of a micrometre-sized magnet with a semiconductor device has enabled the individual manipulation of two single electron spins. This approach may provide a scalable route for quantum computing with electron spins confined in quantum dots.

M. Pioro-Ladrière
T. Obata
S. Tarucha
Research17 Aug 2008
Nature Physics

Volume: 4, P: 776-779
Microsatellite instability in female non-small-cell lung cancer patients with familial clustering of malignancy

K Suzuki
T Ogura
H Esumi
Research01 Mar 1998
British Journal of Cancer

Volume: 77, P: 1003-1008
Fluorescent nucleobases as tools for studying DNA and RNA

The emergence of synthetic fluorescent nucleobases that can be incorporated into DNA and RNA in place of their natural counterparts has enabled new tools and technologies with applications in chemistry, biology and biomedicine. This Review discusses chemical insights into canonical and non-canonical nucleobase designs, relating structure to properties.

Wang Xu
Ke Min Chan
Eric T. Kool
Reviews16 Oct 2017
Nature Chemistry

Volume: 9, P: 1043-1055
Dairy products and colorectal cancer. A review of possible mechanisms and epidemiological evidence

T Norat
E Riboli
Reviews27 Jan 2003
European Journal of Clinical Nutrition

Volume: 57, P: 1-17
Low BCL-2 expression in acute leukemia with t(8;21) chromosomal abnormality

M Shikami
H Miwa
K Kita
Research10 Mar 1999
Leukemia

Volume: 13, P: 358-368
Identification of Kawasaki Disease (KD) Antigens Using Synthetic KD Antibodies

Anne H Rowley
Susan C Baker
Stanford T Shulman
Research01 Jan 2003
Pediatric Research

Volume: 53, P: 160
Nine- or fewer repeat alleles in VNTR polymorphism of the dopamine transporter gene is a strong risk factor for prolonged methamphetamine psychosis

H Ujike
M Harano
N Ozaki
Research20 Aug 2003
The Pharmacogenomics Journal

Volume: 3, P: 242-247
Biphasic expression of CD4 in acute myelocytic leukemia (AML) cells: AML of monocyte origin and hematopoietic precursor cell origin

H Miwa
M Mizutani
K Kita
Research01 Apr 1998
Leukemia

Volume: 12, P: 44-51

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