Nature Search

Knud Hermann Nierhaus 1941–2016

Daniel N Wilson
Christian M T Spahn
Comments & Opinion07 Jun 2016
Nature Structural & Molecular Biology

Volume: 23, P: 503-504
Hermann Kopp

T. E. THORPE
News10 Mar 1892
Nature

Volume: 45, P: 441-442
An implantable system to restore hemodynamic stability after spinal cord injury

A purpose-built implantable system based on biomimetic epidural electrical stimulation of the spinal cord reduces the severity of hypotensive complications in people with spinal cord injury and improves quality of life.

Aaron A. Phillips
Aasta P. Gandhi
Grégoire Courtine
ResearchOpen Access17 Sept 2025
Nature Medicine

Volume: 31, P: 2946-2957
In vivo itaconate tracing reveals degradation pathway and turnover kinetics

In this study, Willenbockel et al. trace circulating itaconate in vivo to gain insight into its fate and systemic metabolism.

Hanna F. Willenbockel
Alexander T. Williams
Thekla Cordes
ResearchOpen Access10 Sept 2025
Nature Metabolism

Volume: 7, P: 1781-1790
Transfer Function of a Biological Photoreceptor

LAWRENCE STARK
HOWARD T. HERMANN
Research16 Sept 1961
Nature

Volume: 191, P: 1173-1174
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Guessing as a Form of Intelligent Behaviour

R. T. GREEN
B. G. STACEY
Research14 May 1966
Nature

Volume: 210, P: 673-675
Regional heterogeneity of the blood-brain barrier

The blood-brain barrier (BBB) regulates the extracellular composition of the central nervous system (CNS), but it is not known whether its properties differ across CNS regions. Here, the authors show in mice that the BBB exhibits regional specializations, and that such specializations can be important for the function of specific neural circuits.

Marie Blanchette
Kaja Bajc
Richard Daneman
ResearchOpen Access08 Aug 2025
Nature Communications

Volume: 16, P: 1-14
Measurement of phonon angular momentum

Theory predicts that phonons—quanta of lattice vibrations—can carry finite angular momentum and thus influence physical properties of materials. Now phonons with angular momentum have been seen in tellurium with a chiral crystal structure.

H. Zhang
N. Peshcherenko
H. Miao
Research11 Jul 2025
Nature Physics

Volume: 21, P: 1387-1391
Potentiation of Epinephrine Effects by Flavonoid Compounds

WILLIAM G. CLARK
T. A. GEISSMAN
Research01 Jan 1949
Nature

Volume: 163, P: 36-37
Natural products in drug discovery: advances and opportunities

Natural products have historically made a major contribution to pharmacotherapy, but also present challenges for drug discovery, such as technical barriers to screening, isolation, characterization and optimization. This Review discusses recent technological developments — including improved analytical tools, genome mining and engineering strategies, and microbial culturing advances — that are enabling a revitalization of natural product-based drug discovery.

Atanas G. Atanasov
Sergey B. Zotchev
Claudiu T. Supuran
Reviews28 Jan 2021
Nature Reviews Drug Discovery

Volume: 20, P: 200-216
Enzymatic Coagulation of Semen

G. GOTTERER
D. GINSBERG
H. G. WILLIAMS-ASHMAN
Research24 Dec 1955
Nature

Volume: 176, P: 1209-1211
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Author Correction: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

Kate Lawrenson
Siddhartha Kar
Simon A. Gayther
Amendments and CorrectionsOpen Access08 Sept 2025
Nature Communications

Volume: 16, P: 1-2
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Analyses of 2,658 whole genomes across 38 types of cancer identify the contribution of non-coding point mutations and structural variants to driving cancer.

Esther Rheinbay
Morten Muhlig Nielsen
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature

Volume: 578, P: 102-111
The massed-spaced learning effect in non-neural human cells

When learning is spaced in time, memory is enhanced, but so far this was only observed in neural systems. Here, the authors show that non-neural cells, including kidney cells, also show a spaced effect in terms of transcriptional responses.

N. V. Kukushkin
R. E. Carney
T. J. Carew
ResearchOpen Access07 Nov 2024
Nature Communications

Volume: 15, P: 1-10
Comparison of neurodevelopmental outcomes of extremely preterm infants undergoing trans-catheter closure of the patent ductus arteriosus compared to surgical ligation

D. C. Kaluarachchi
V. Y. Chock
G. Natarajan
ResearchOpen Access23 Sept 2025
Journal of Perinatology

P: 1-7
Deletion of the TSC2 and PKD1 genes associated with severe infantile polycystic kidney disease — a contiguous gene syndrome

Phillip T. Brook-Carter
Belén Peral
Julian R. Sampson
Research01 Dec 1994
Nature Genetics

Volume: 8, P: 328-332
Reaction of Lime with Ferric Oxide

A. K. CHATTERJI
T. C. PHATAK
Research26 Jan 1963
Nature

Volume: 197, P: 350-352
Slip-line field theory and large-scale continental tectonics

Paul Tapponnier
Peter Molnar
Research25 Nov 1976
Nature

Volume: 264, P: 319-324
North and Central European Flora

T. G. TUTIN
Research05 Apr 1958
Nature

Volume: 181, P: 972-973
The multiple benefits of Chinese dietary transformation

The transition to sustainable diets is challenging for countries that face malnutrition and limited resources. Now a study explores how various dietary transformations in China can improve public health, make food affordable and reduce environmental impacts, while evaluating the feasibility of the diet changes.

Hao Cai
Jiaqi Xuan
Hermann Lotze-Campen
Research06 May 2025
Nature Sustainability

Volume: 8, P: 606-618
On The Nature Of Inhibition, And The Action Of Drugs Upon It

T. LAUDER BRUNTON
Research01 Mar 1883
Nature

Volume: 27, P: 419-422
Hydrogen-bonded frameworks for molecular structure determination

Single crystal X-ray diffraction is an invaluable tool for molecular structure determination, but growing single crystals is often an arduous process. Here the authors find that the structures of a wide array of molecules can be determined by SCXRD when included in hydrogen-bonded guanidinium organosulfonate host frameworks in a single-step crystallization.

Yuantao Li
Sishuang Tang
Michael D. Ward
ResearchOpen Access02 Oct 2019
Nature Communications

Volume: 10, P: 1-7
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Here, the authors perform large trans-ancestry fine-mapping analyses identifying large numbers of association signals and putative target genes for colorectal cancer risk, advancing our understanding of the genetic and biological basis of this cancer.

Zhishan Chen
Xingyi Guo
Wei Zheng
ResearchOpen Access26 Apr 2024
Nature Communications

Volume: 15, P: 1-17
Crystal structure of the high-temperature superconductor TI₂Ba₂CaCu₂O₈

M. A. Subramanian
J. C. Calabrese
A. W. Sleight
Research31 Mar 1988
Nature

Volume: 332, P: 420-422
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS

Plasma extracellular vesicles contain quantifiable amounts of TDP-43 and full-length tau, allowing the accurate assessment of pathology in frontotemporal dementia, frontotemporal dementia spectrum disorders and amyotrophic lateral sclerosis.

Madhurima Chatterjee
Selcuk Özdemir
Anja Schneider
ResearchOpen Access18 Jun 2024
Nature Medicine

Volume: 30, P: 1771-1783
Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome

Zeiser and colleagues show that CAR T cell therapy results in upregulation of the TGFβ-activated kinase-1 (TAK1)–NF-κB–p38 MAPK pathway in microglia, causing neurocognitive defects, and find that TAK1 inhibition can reduce immune effector cell-associated neurotoxicity syndrome.

Janaki Manoja Vinnakota
Francesca Biavasco
Robert Zeiser
Research13 May 2024
Nature Cancer

Volume: 5, P: 1227-1249
Meta-analyses identify DNA methylation associated with kidney function and damage

Many genetic loci have been identified to be associated with kidney disease, but the molecular mechanisms are not well understood. Here, the authors perform epigenome-wide association studies on kidney function measures to identify epigenetic marks and pathways involved in kidney function.

Pascal Schlosser
Adrienne Tin
Alexander Teumer
ResearchOpen Access09 Dec 2021
Nature Communications

Volume: 12, P: 1-16
Burrowing Larvæ

V. T. CHAMBERS
Research06 Apr 1882
Nature

Volume: 25, P: 529
Early postnatal echocardiographic characteristics impact survival and extracorporeal life support in congenital diaphragmatic hernia

Caroline Y. Noh
Enrico Danzer
Krisa P. Van Meurs
Research01 Oct 2025
Pediatric Research

P: 1-8
A unique geochemical record at the Permian/Triassic boundary

William T. Holser
Hans-Peter Schönlaub
Rupert Schmöller
Research05 Jan 1989
Nature

Volume: 337, P: 39-44
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus

Serum urate concentration can be studied in large datasets to find genetic and epigenetic loci that may be related to cardiometabolic traits. Here the authors identify and replicate 100 urate-associated CpGs, which provide insights into urate GWAS loci and shared CpGs of urate and cardiometabolic traits.

Adrienne Tin
Pascal Schlosser
Anna Köttgen
ResearchOpen Access09 Dec 2021
Nature Communications

Volume: 12, P: 1-18
Growth of superconducting single crystals in the Bi–Sr–Ca–Cu–O system from alkali chloride fluxes

L. F. Schneemeyer
R. B. van Dover
L. W. Rupp
Research31 Mar 1988
Nature

Volume: 332, P: 422-424
Anomalous thickness dependence of the vortex pearl length in few-layer NbSe₂

In superconducting thin films of a few atomic layers, surface and bulk orders may compete. Here, the authors measure how the Pearl length, which characterizes the distribution of magnetic field in vortices, varies with thickness in NbSe₂, showing that surface superconductivity dominates at low thickness.
Peer review information: Nature Communications thanks Martino Poggio, and the other, anonymous, reviewers for their contribution to the peer review of this work. A peer review file is available.

Nofar Fridman
Tomer Daniel Feld
Yonathan Anahory
ResearchOpen Access31 Mar 2025
Nature Communications

Volume: 16, P: 1-7
A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer

The PSA (KLK3) genetic variant rs17632542 is associated with reduced prostate cancer risk and lower serum PSA levels, although the underlying reasons are unclear. Here, the authors show that this PSA variant reduced proteolytic activity and leads to smaller tumours, but also increases invasion and bone metastasis, indicating its dual risk association depending on tumour context; the variant is associated with both lower risk and poor clinical outcomes.

Srilakshmi Srinivasan
Thomas Kryza
Jyotsna Batra
ResearchOpen Access06 Nov 2024
Nature Communications

Volume: 15, P: 1-21
The contribution of de novo coding mutations to meningomyelocele

Exome sequencing of 851 trios from more than 2,500 individuals finds 187 genes with de novo mutations that contribute to meningomyelocele (spina bifida) and highlights critical pathways required for neural tube closure.

Yoo-Jin Jiny Ha
Ashna Nisal
Joseph G. Gleeson
Research26 Mar 2025
Nature

Volume: 641, P: 419-426
Sex ratio evolution in a variable environment

E. L. Charnov
R. L. Los-den Hartogh
J. van den Assem
Research01 Jan 1981
Nature

Volume: 289, P: 27-33
Local probe of single phonon dynamics in warm ion crystals

An exhausting characterization of the coherence properties of quantum system becomes challenging with increasing system size. Here the authors demonstrate that phonon autocorrelation functions and quantum discord can be measured with local control, and validate it in a string of 42 trapped ions.

A. Abdelrahman
O. Khosravani
H. Häffner
ResearchOpen Access09 Jun 2017
Nature Communications

Volume: 8, P: 1-5
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

Most genetic studies have been done on European cohorts, which affects the efficacy of polygenic risk scores in non-European populations. Here, the authors demonstrate that a colorectal cancer PRS including Asian and European ancestries has improved performance over the European-centric PRS across racial and ethnic groups.

Minta Thomas
Yu-Ru Su
Li Hsu
ResearchOpen Access02 Oct 2023
Nature Communications

Volume: 14, P: 1-13
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Fine-mapping of causal variants and integration of epigenetic and chromatin conformation data identify likely target genes for 150 breast cancer risk regions.

Laura Fachal
Hugues Aschard
Alison M. Dunning
Research07 Jan 2020
Nature Genetics

Volume: 52, P: 56-73
Chronic kidney disease and incident cancer risk: an individual participant data meta-analysis

Yejin Mok
Aditya Surapaneni
Michael G. Shlipak
ResearchOpen Access06 Sept 2025
British Journal of Cancer

P: 1-9
Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T–T cell interactions

Deming Sun
Yufen Qin
Hartmut Wekerle
Research28 Apr 1988
Nature

Volume: 332, P: 843-845
Interlayer effects in high-T_c superconductors

J. M. WHEATLEY
T. C. HSU
P. W. ANDERSON
Research12 May 1988
Nature

Volume: 333, P: 121
Combined Inhibition of Influenza Virus Reproduction in Cell Culture using Interferon and Amantadine

S. V. LAVROV
E. I. EREMKINA
V. M. ZHDANOV
Research02 Mar 1968
Nature

Volume: 217, P: 856-857
Thermal Expansion of Rubidium Dihydrogen Phosphate

V. T. DESHPANDE
A. A. KHAN
Research05 Feb 1966
Nature

Volume: 209, P: 608
A new high-T_c TlBa₂Ca₃Cu₄O₁₁ superconductor with T_c >120K

H. Ihara
R. Sugise
T. Shimomura
Research01 Aug 1988
Nature

Volume: 334, P: 510-511
Interaction between neuropeptide Y and noradrenaline on central catecholamine neurons

P. Illes
J. T. Regenold
Research01 Mar 1990
Nature

Volume: 344, P: 62-63
Understanding the genetic complexity of puberty timing across the allele frequency spectrum

A multi-ancestry genome-wide association study for age at menarche followed by fine mapping and downstream analysis implicates 665 pubertal timing genes, such as the G-protein-coupled receptor 83 (GPR83) and other genes expressed in the ovaries involved in the DNA damage response.

Katherine A. Kentistou
Lena R. Kaisinger
Ken K. Ong
ResearchOpen Access01 Jul 2024
Nature Genetics

Volume: 56, P: 1397-1411
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

A multi-ancestry genome-wide association study meta-analysis, combined with transcriptome- and methylome-wide association analyses, identifies risk loci associated with colorectal cancer. Credible effector genes and their target tissues are also highlighted, showing that over a third probably act outside the colonic mucosa.

Ceres Fernandez-Rozadilla
Maria Timofeeva
Ulrike Peters
Research20 Dec 2022
Nature Genetics

Volume: 55, P: 89-99

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