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Scientific Reports (9)
Journal of Human Genetics (1)
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Showing 1–15 of 15 results

Advanced filters: Author: Takahiko Imai Clear advanced filters

Treatment of a severe vascular disease using a bespoke CRISPR–Cas9 base editor in mice

Engineering a mutant-specific customized base editor precisely corrects a mutation while minimizing bystander edits, leading to substantial phenotypic recovery in mouse models of multisystemic smooth muscle dysfunction syndrome.

Christiano R. R. Alves
Sabyasachi Das
Patricia L. Musolino
Research11 Sept 2025
Nature Biomedical Engineering

P: 1-16
Biogenic filamentous fabrics in green colored moss agates within miocene volcanic rocks in Japan and the associated formation of celadonite

Hisatada Akahane
Masaaki Shimizu
Hiroyuki Imai
ResearchOpen Access11 Jul 2025
Scientific Reports

Volume: 15, P: 1-9
The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells

Liqin Cao
Hiroshi Shitara
Hiromichi Yonekawa
Research11 Feb 2007
Nature Genetics

Volume: 39, P: 386-390
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Effects of ticagrelor in a mouse model of ischemic stroke

Keita Yamauchi
Takahiko Imai
Hideaki Hara
ResearchOpen Access21 Sept 2017
Scientific Reports

Volume: 7, P: 1-10
Non-muscle myosin IIA is a functional entry receptor for herpes simplex virus-1

Entry of herpes simplex virus-1 into cells requires cellular receptors for both envelope glycoprotein B and envelope glycoprotein D. These authors show that the interaction of non-muscle myosin heavy chain IIA with envelope glycoprotein B is important for entry of herpes simplex virus-1.

Jun Arii
Hideo Goto
Yasushi Kawaguchi
Research13 Oct 2010
Nature

Volume: 467, P: 859-862
Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis

Keiji Kobayashi
Hidetoshi Nojiri
Takahiko Shimizu
ResearchOpen Access16 Mar 2015
Scientific Reports

Volume: 5, P: 1-11
Simulating metabolic pathways to enhance interpretations of metabolome genome-wide association studies

Shun Kodate
Mitsuharu Sato
Kengo Kinoshita
ResearchOpen Access16 May 2025
Scientific Reports

Volume: 15, P: 1-11
Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank

Aye Ko Ko Minn
Motomichi Matsuzaki
Gen Tamiya
ResearchOpen Access03 Apr 2025
Journal of Human Genetics

Volume: 70, P: 287-296
Association between human papillomavirus particle production and the severity of recurrent respiratory papillomatosis

Satoshi Yamada
Toshiya Itoh
Hideya Kawasaki
ResearchOpen Access06 Apr 2023
Scientific Reports

Volume: 13, P: 1-13
MYCL promotes iPSC-like colony formation via MYC Box 0 and 2 domains

Chiaki Akifuji
Mio Iwasaki
Masato Nakagawa
ResearchOpen Access20 Dec 2021
Scientific Reports

Volume: 11, P: 1-30
Intracellular Fe²⁺ accumulation in endothelial cells and pericytes induces blood-brain barrier dysfunction in secondary brain injury after brain hemorrhage

Takahiko Imai
Sena Iwata
Hideaki Hara
ResearchOpen Access17 Apr 2019
Scientific Reports

Volume: 9, P: 1-16
Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia

Keiko Doi
Takahiko Imai
Nagahiro Minato
ResearchOpen Access23 Jan 2015
Scientific Reports

Volume: 5, P: 1-8
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Hiroki Masuda
Masahiro Mori
Satoshi Kuwabara
ResearchOpen Access03 Aug 2023
Scientific Reports

Volume: 13, P: 1-14
Discontinuation of antidepressants after remission with antidepressant medication in major depressive disorder: a systematic review and meta-analysis

Masaki Kato
Hikaru Hori
Aran Tajika
ReviewsOpen Access23 Jul 2020
Molecular Psychiatry

Volume: 26, P: 118-133