Stereoselective synthesis of tetrahydro-βcarboline skeletons have immense impacts and attract enormous attention. Here, the authors report chiral phosphoric acid catalyzed asymmetric 1,3-dipolar cycloaddition, affording three types of chiral tetrahydro-β-carbolines bearing continuous multi-chiral centers and quaternary chiral centers.
- Xiaochen Tian
- Tengfei Xuan
- Yang Wang
