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Showing 1–50 of 153 results

Advanced filters: Author: Thomas Harding Clear advanced filters

Upper mantle origin for Harding County well gases

Thomas Staudacher
Research18 Feb 1987
Nature

Volume: 325, P: 605-607
R_M Values in the Gas-Liquid Chromatography of Steroids

B. A. KNIGHTS
G. H. THOMAS
Research02 Jun 1962
Nature

Volume: 194, P: 833-835
Structure of a family of rat amylase genes

Raymond J. MacDonald
Michael M. Crerar
William J. Rutter
Research11 Sept 1980
Nature

Volume: 287, P: 117-122
Dentine in conodonts

Ivan J. Sansom
M. Paul Smith
Moya M Smith
Research14 Apr 1994
Nature

Volume: 368, P: 591
Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

Gunter Fischer
Brigitte Wittmann-Liebold
Franz X. Schmid
Research02 Feb 1989
Nature

Volume: 337, P: 476-478
Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system

Thomas C. Harding
Brad J. Geddes
James B. Uney
Research01 Jun 1998
Nature Biotechnology

Volume: 16, P: 553-555
Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

Gary A. Koretzky
Joel Picus
Arthur. Weiss
Research05 Jul 1990
Nature

Volume: 346, P: 66-68
Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection

Understanding the mechanisms behind clinical immunity to malaria is crucial for developing effective interventions. Here, the authors demonstrate that clinical immunity to Plasmodium vivax develops rapidly after a single controlled human malaria infection, reducing inflammatory responses and protecting against symptoms, while not significantly affecting parasite load.

Mimi M. Hou
Adam C. Harding
Angela M. Minassian
ResearchOpen Access25 Sept 2025
Nature Communications

Volume: 16, P: 1-13
Peripheral myelin protein–22 gene maps in the duplication in chromosome 17p11.2 associated with Charcot–Marie–Tooth 1A

Norisada Matsunami
Brooke Smith
Phillip F. Chance
Research01 Jun 1992
Nature Genetics

Volume: 1, P: 176-179
Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1

Harry T. Orr
Ming-yi Chung
Huda Y. Zoghbi
Research01 Jul 1993
Nature Genetics

Volume: 4, P: 221-226
Charcot–Marie–Tooth neuropathy type 1B is associated with mutations of the myelin P₀ gene

Kiyoshi Hayasaka
Masato Himoro
Phillip F. Chance
Research01 Sept 1993
Nature Genetics

Volume: 5, P: 31-34
Direct detection of novel expanded trinucleotide repeats in the human genome

Martin Schalling
Thomas J. Hudson
David E. Housman
Research01 Jun 1993
Nature Genetics

Volume: 4, P: 135-139
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Interpretation of a selection plateau through complex segregation analysis: Euclidean distance index selection for flower colour in the Davis population of Gerbera

Kenneth R Tourjee
James Harding
Thomas G Byrne
Research01 Sept 1995
Heredity

Volume: 75, P: 290-296
Bottom Melting of Ice Shelves and the Mass Balance of Antarctica

R. H. THOMAS
P. H. COSLETT
Research03 Oct 1970
Nature

Volume: 228, P: 47-49
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Urinary II-Deoxy-17-oxosteroids in British and Japanese Women with Reference to the Incidence of Breast Cancer

R. D. BULBROOK
B. S. THOMAS
J. UTSUNOMIYA
Research11 Jan 1964
Nature

Volume: 201, P: 189-190
Competitive Inhibition of Mammalian Tyrosinase by Phenylalanine and its Relationship to Hair Pigmentation in Phenylketonuria

MASAMITSU MIYAMOTO
THOMAS B. FITZPATRICK
Research26 Jan 1957
Nature

Volume: 179, P: 199-200
The biology of history

Hugh Thomas
Books & Arts15 Jan 1981
Nature

Volume: 289, P: 208-209
A common molecular basis for three inherited kidney stone diseases

Sarah E. Lloyd
Simon H. S. Pearce
Rajesh V. Thakker
Research01 Feb 1996
Nature

Volume: 379, P: 445-449
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
The International Primary Care Respiratory Group (IPCRG) Research Needs Statement 2010

Hilary Pinnock
Mike Thomas
Sian Williams
Research31 May 2010
Primary Care Respiratory Journal

Volume: 19, P: S1-S20
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin

Vijay K. Chaudhary
Gary Queen
Ira Pastan
Research01 Jun 1989
Nature

Volume: 339, P: 394-397
DRPLA in Europe

Thomas T. Warner
Lee Williams
Anita E. Harding
Correspondence01 Mar 1994
Nature Genetics

Volume: 6, P: 225
Fibroblast growth factor 2 control of vascular tone

Ming Zhou
Roy L. Sutliff
Thomas Doetschman
Research01 Feb 1998
Nature Medicine

Volume: 4, P: 201-207
Exploration of refined humane endpoints for melioidosis in BALB/c mice

The authors analyzed four melioidosis studies in mice to identify refined humane endpoints (25% weight loss and/or clinical score ≥5) that improve animal welfare while maintaining study integrity.

Michael P. Harris
Kay B. Barnes
Thomas C. Maishman
ResearchOpen Access06 Jan 2026
Lab Animal

Volume: 55, P: 40-47
Characterizing trachoma elimination using serology

The study advances the use of serological surveys to guide trachoma elimination program decisions and provides a way to set thresholds for whether or not to continue an intervention program.

Everlyn Kamau
Pearl Anne Ante-Testard
Benjamin F. Arnold
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-14
Trust in scientists and their role in society across 68 countries

What is the state of trust in scientists around the world? To answer this question, the authors surveyed 71,922 respondents in 68 countries and found that trust in scientists is moderately high.

Viktoria Cologna
Niels G. Mede
Rolf A. Zwaan
ResearchOpen Access20 Jan 2025
Nature Human Behaviour

Volume: 9, P: 713-730
Isolation of a Miller–Dicker lissencephaly gene containing G protein β-subunit-like repeats

Orly Reiner
Romeo Carrozzo
David H. Ledbetter
Research19 Aug 1993
Nature

Volume: 364, P: 717-721
Molecular size of retinal vascular leakage determined by FITC-dextran angiography in patients with posterior uveitis

E G Atkinson
S Jones
E Graham
Research01 Jul 1991
Eye

Volume: 5, P: 440-446
The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness

Thomas, Egan et al. report that hexokinase 2 localizes to the nucleus of leukaemic and normal haematopoietic cells to maintain stemness by interacting with nuclear proteins and modulating chromatin accessibility independently of its kinase activity.

Geethu Emily Thomas
Grace Egan
Aaron D. Schimmer
ResearchOpen Access06 Jun 2022
Nature Cell Biology

Volume: 24, P: 872-884
Mimicry of antenna and photo-protective carotenoid functions by a synthetic carotenoporphyrin

René V. Bensasson
Edward J. Land
Devens Gust
Research26 Mar 1981
Nature

Volume: 290, P: 329-332
Extreme weather event attribution predicts climate policy support across the world

Literature produced inconsistent findings regarding the links between extreme weather events and climate policy support across regions, populations and events. This global study offers a holistic assessment of these relationships and highlights the role of subjective attribution.

Viktoria Cologna
Simona Meiler
Amber Zenklusen
ResearchOpen Access01 Jul 2025
Nature Climate Change

Volume: 15, P: 725-735
Self-assembly of a double-helical complex of sodium

Thomas W. Bell
Hélène Jousselin
Research03 Feb 1994
Nature

Volume: 367, P: 441-444
Are linkage studies boring?

Thomas D. Bird
News & Views01 Jul 1993
Nature Genetics

Volume: 4, P: 213-214
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

Transancestral GWAS meta-analysis in 160,420 individuals identifies 139 loci associated with refractive error, including myopia. Newly identified genes implicate pathways involved in eye growth and light signaling cascades.

Milly S. Tedja
Robert Wojciechowski
Caroline C. W. Klaver
Research28 May 2018
Nature Genetics

Volume: 50, P: 834-848
Complex segregation analysis of Gerbera flower colour

Kenneth R Tourjee
James Harding
Thomas G Byrne
Research01 Mar 1995
Heredity

Volume: 74, P: 303-310
Oestrogen receptor protein and mRNA in adenocarcinoma of the uterine cervix

SM Ismail
GA Thomas
ED Williams
Research01 Dec 1992
British Journal of Cancer

Volume: 66, P: 1150-1154
Protein–like fully reversible tetramerisation and super-association of an aminocellulose

Melanie Nikolajski
Gary G. Adams
Stephen E. Harding
ResearchOpen Access24 Jan 2014
Scientific Reports

Volume: 4, P: 1-5
Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3

Marta Chesi
Elena Nardini
P. Leif Bergsagel
Research01 Jul 1997
Nature Genetics

Volume: 16, P: 260-264
Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

Xiao-kun Zhang
Jürgen Lehmann
Magnus Pfahl
Research13 Aug 1992
Nature

Volume: 358, P: 587-591
Solution structure of the cyclosporin A/cyclophilin complex by NMR

Yves Thériault
Timothy M. Logan
Stephen W. Fesik
Research07 Jan 1993
Nature

Volume: 361, P: 88-91
A Diminished Role for the Sarcoplasmic Reticulum in Newborn Myocardial Contraction: Effects of Ryanodine

Thomas S Klitzner
William F Friedman
Research01 Aug 1989
Pediatric Research

Volume: 26, P: 98-101
Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay

In Drosophila, ER-targeted mRNAs are degraded by Ire1-dependent pathway. Here the authors report that the fly mRNA binding protein Pumilio is phosphorylated by Ire1 and binds to Xbp1 mRNA, protecting it from the non-canonical endoribonuclease activity of Ire1.

Fátima Cairrão
Cristiana C. Santos
Pedro M. Domingos
ResearchOpen Access24 Mar 2022
Nature Communications

Volume: 13, P: 1-13
Correction: Corrigendum: Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients

Jacob J. Chabon
Andrew D. Simmons
Maximilian Diehn
Amendments and CorrectionsOpen Access14 Nov 2016
Nature Communications

Volume: 7, P: 1
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern

Understanding the effect of vaccination on emerging SARS-CoV-2 variants of concern is of increasing importance. Here, James et al. report that two doses of vaccination with the Pfizer-BioNTech vaccine induce more robust immune responses to the B.1.1.7 and B.1.351 SARS-CoV-2 lineages than does natural infection.

Donal T. Skelly
Adam C. Harding
William S. James
ResearchOpen Access17 Aug 2021
Nature Communications

Volume: 12, P: 1-12
Retroperitoneoscopic nephrectomy for giant hydronephrosis in pregnancy

This Case Study describes a 32-year-old pregnant woman who presented with severe pain and a left-sided giant hydronephrosis. Renal ultrasonography, intravenous urography and MAG-3 renography confirmed pelvi-ureteric junction obstruction, so a left retroperitoneoscopic nephrectomy was performed. The authors discuss the risks associated with surgical treatment of the pregnant patient.

Heleni Mastoroudes
Jonathon Olsburgh
Prokar Dasgupta
Reviews01 Sept 2007
Nature Clinical Practice Urology

Volume: 4, P: 512-515

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