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Showing 1–6 of 6 results
Advanced filters: Author: Thomas Schiex Clear advanced filters

  • Computational protein design uses information on the constraints of the biological and physical properties of proteins for protein engineering and de novo protein design. In this Primer, Albanese et al. give an overview of the guiding principles of computational protein design and its considerations, methods and applications and conclude by discussing the future of the technique in the context of rapidly advancing computational tools.

    • Katherine I. Albanese
    • Sophie Barbe
    • Thomas Schiex
    Reviews
    Nature Reviews Methods Primers
    Volume: 5, P: 1-28

  • Biological control of the root-knot nematode Meloidogyne incognita, one of the world's most destructive crop pathogens, presents a major opportunity for safely improving global agricultural yields. Its 86-Mb genome—the first to be sequenced for a strictly parthenogenetic species—provides a blueprint to design new strategies for plant protection.

    • Pierre Abad
    • Jérôme Gouzy
    • Patrick Wincker
    ResearchOpen Access
    Nature Biotechnology
    Volume: 26, P: 909-915

  • Xavier Argout and colleagues report the draft genome of Theobroma cacao, the tropical crop that is the source of chocolate. The sequence assembly covers approximately 80% of the genome.

    • Xavier Argout
    • Jerome Salse
    • Claire Lanaud
    ResearchOpen Access
    Nature Genetics
    Volume: 43, P: 101-108

  • This paper reports the genome sequence of domesticated tomato, a major crop plant, and a draft sequence for its closest wild relative; comparative genomics reveal very little divergence between the two genomes but some important differences with the potato genome, another important food crop in the genus Solanum.

    • Shusei Sato
    • Satoshi Tabata
    • René M. Klein Lankhorst
    ResearchOpen Access
    Nature
    Volume: 485, P: 635-641