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Showing 1–14 of 14 results
Advanced filters: Author: Tirin Moore Clear advanced filters

  • Neuropixels 1.0 NHP is a 45-mm, high-density silicon probe capable of recording large numbers of neurons with single-neuron resolution from most areas in a macaque’s brain.

    • Eric M. Trautmann
    • Janis K. Hesse
    • Timothy Harris
    ResearchOpen Access
    Nature Neuroscience
    Volume: 28, P: 1562-1575

  • Saccadic eye movements cause substantial shifts in the retinal image as we take in visual scenes, but our perception is stable and continuous; here, visual receptive fields are shown to shift dramatically towards the saccadic goal, running counter to the long-standing hypothesis of receptive field remapping as the basis of perceived stability.

    • Marc Zirnsak
    • Nicholas A. Steinmetz
    • Tirin Moore
    Research
    Nature
    Volume: 507, P: 504-507

  • By recording large populations of neurons in behaving monkeys using newly developed silicon probes, we show that intermittent periods of memorandum-specific spiking coexist with synaptic mechanisms to support working memory. 

    • Matthew F. Panichello
    • Donatas Jonikaitis
    • Tirin Moore
    ResearchOpen Access
    Nature
    Volume: 636, P: 422-429

  • The ability to filter out distracting sensory information is crucial to adaptive behavior. A primate study finds that prefrontal cortex is more important than parietal cortex in that function.

    • Behrad Noudoost
    • Tirin Moore
    News & Views
    Nature Neuroscience
    Volume: 16, P: 8-9

  • Not much is known about how intrinsic timescales, which characterize the dynamics of endogenous fluctuations in neural activity, change during cognitive tasks. Here, the authors show that intrinsic timescales of neural activity in the primate visual cortex change during spatial attention. Experimental data were best explained by a network model in which timescales arise from spatially arranged connectivity.

    • Roxana Zeraati
    • Yan-Liang Shi
    • Tatiana A. Engel
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-19

  • Frontal eye field (FEF) is a visual prefrontal area involved in top-down attention. Here the authors report that FEF neurons projecting to V4/MT are persistently active during spatial working memory, and V4/MT neurons show changes in receptive field and gain at the location held in working memory.

    • Yaser Merrikhi
    • Kelsey Clark
    • Behrad Noudoost
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-10

  • Here, the authors show that beta-band coordination between prefrontal and temporal cortex predicts working memory performance. Moreover, inferior temporal neurons exhibits greater memory activity when coordination between these areas is high, suggesting that this interaction supports object memory maintenance.

    • Ehsan Rezayat
    • Mohammad-Reza A. Dehaqani
    • Behrad Noudoost
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • The authors measured the variability of neuronal responses across a large number of datasets and cortical areas. They found that variability decreased in response to all stimuli tested, whether the animal was awake, behaving or anesthetized, suggesting that the stabilization of cortex in response to an input is a general cortical property.

    • Mark M Churchland
    • Byron M Yu
    • Krishna V Shenoy
    Research
    Nature Neuroscience
    Volume: 13, P: 369-378

  • Exploring the relationship between population coupling and neuronal activity reveals that neighbouring neurons can differ in their coupling to the overall firing rate of the population, the circuitry of which may potentially help to explain the complex activity patterns in cortical populations.

    • Michael Okun
    • Nicholas A. Steinmetz
    • Kenneth D. Harris
    Research
    Nature
    Volume: 521, P: 511-515