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Scientific Reports (20)
Hypertension Research (10)
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Showing 1–50 of 54 results

Advanced filters: Author: Tomoko Nakayama Clear advanced filters

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin

Paulo A. Ferreira
Tomoko A. Nakayama
Gabriel H. Travis
Research17 Oct 1996
Nature

Volume: 383, P: 637-640
Chelation-based iron uptake mitigates the effects of prolonged high-temperature stress in cool-season grasses

How plants mitigate the negative effects of exposure to continuous, moderately high temperatures remains underexplored. Here, the authors report the role of chelation-based iron uptake in mitigating prolonged high-temperature in cool-season grasses, specifically Brachypodium distachyon and wheat.

Anzu Minami
Yoshihiko Onda
Keiichi Mochida
ResearchOpen Access28 Aug 2025
Nature Communications

Volume: 16, P: 1-15
An unnatural base pair for incorporating amino acid analogs into proteins

Ichiro Hirao
Takashi Ohtsuki
Shigeyuki Yokoyama
Research01 Feb 2002
Nature Biotechnology

Volume: 20, P: 177-182
VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A Harrington
David Bebbington
Karen M Miller
Research22 Feb 2004
Nature Medicine

Volume: 10, P: 262-267
FR258900, a Novel Glycogen Phosphorylase Inhibitor Isolated from Fungus No. 138354

Shigetada Furukawa
Yasuhisa Tsurumi
Motohiro Hino
Research01 Aug 2005
The Journal of Antibiotics

Volume: 58, P: 497-502
Addendum: VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A Harrington
David Bebbington
Karen M Miller
Amendments and Corrections01 Apr 2007
Nature Medicine

Volume: 13, P: 511
Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Youngjune Bhak
Vasilis Raptis
Albert Tenesa
ResearchOpen Access28 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
A ground-like surface facilitates visual search in chimpanzees (Pan troglodytes)

Tomoko Imura
Masaki Tomonaga
ResearchOpen Access06 Aug 2013
Scientific Reports

Volume: 3, P: 1-4
Association between urinary sodium-to-potassium ratio and BNP in a general population without antihypertensive treatment and cardiovascular diseases: the Ohasama study

Tomoko Muroya
Michihiro Satoh
Takayoshi Ohkubo
ResearchOpen Access27 Jun 2025
Hypertension Research

Volume: 48, P: 2292-2302
Comparison of two families with and without ataxia harboring novel variants in PRKCG

Yui Tada
Kodai Kume
Hideshi Kawakami
Research28 Jun 2022
Journal of Human Genetics

Volume: 67, P: 595-599
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
PtdIns(3,5)P₂ mediates root hair shank hardening in Arabidopsis

Root hairs are frequently used to study tip growth in plants. Most of the research was focused on the polarized tip region. Now, a mechanism involving PtdIns(4,5)P₂ and a plant-specific Rho-GTPase is proposed to be required for hardening the shank of growing root hairs.

Tomoko Hirano
Hiroki Konno
Masa H. Sato
Research02 Nov 2018
Nature Plants

Volume: 4, P: 888-897
Association of the spot urine sodium-to-potassium ratio with blood pressure is independent of urinary Na and K levels: The Nagahama study

Yukiko Higo
Shunsuke Nagashima
Tomoko Wakamura
Research10 Jun 2019
Hypertension Research

Volume: 42, P: 1624-1630
Frequent nocturnal urination in older men is associated with arterial stiffness: The Nagahama study

Yasuharu Tabara
Takeshi Matsumoto
Fumihiko Matsuda
Research09 Aug 2019
Hypertension Research

Volume: 42, P: 1996-2001
Association between socioeconomic factors and urinary sodium-to-potassium ratio: the Nagahama Study

Makoto Yamashita
Yasuharu Tabara
Tomoko Wakamura
Research14 Sept 2018
Hypertension Research

Volume: 41, P: 973-980
Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models

Here, the authors report bi-functional, wide tropic macrocycles that bind the influenza viral envelope protein hemagglutinin and inhibit virus infection by blocking adsorption and fusion and show efficacy in preventing severe pneumonia at later stages of infection in mouse and non-human primate cynomolgus macaque models.

Makoto Saito
Yasushi Itoh
Michinori Kohara
ResearchOpen Access11 May 2021
Nature Communications

Volume: 12, P: 1-11
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs

Christian Wolfrum
Shuanping Shi
Markus Stoffel
Research16 Sept 2007
Nature Biotechnology

Volume: 25, P: 1149-1157
Control of seed dormancy and germination by DOG1-AHG1 PP2C phosphatase complex via binding to heme

The hormone abscisic acid (ABA) prevents seeds from germination when conditions are not suitable. Here the authors show that DOG1, a positive regulator of germination, impairs ABA signaling via genetic and physical interactions with the AHG1 phosphatase and that DOG1 binding to heme is required for this activity.

Noriyuki Nishimura
Wataru Tsuchiya
Toshimasa Yamazaki
ResearchOpen Access06 Jun 2018
Nature Communications

Volume: 9, P: 1-14
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project

Soichi Ogishima
Satoshi Nagaie
Masayuki Yamamoto
ResearchOpen Access10 Dec 2021
Human Genome Variation

Volume: 8, P: 1-8
Relationship of oral bacterial number with medical hospitalization costs in analysis of Diagnosis Procedure Combination database from single institution in Japan

Hiromi Nishi
Mikihito Kajiya
Hiroyuki Kawaguchi
ResearchOpen Access15 May 2024
Scientific Reports

Volume: 14, P: 1-11
Self-measurement of blood pressure at home using a cuff device for change in blood pressure levels: systematic review and meta-analysis

Michihiro Satoh
Yukako Tatsumi
Takayoshi Ohkubo
ResearchOpen Access21 Nov 2024
Hypertension Research

Volume: 48, P: 574-591
Potentially compromised systemic and local lactate metabolic balance in glaucoma, which could increase retinal glucose and glutamate concentrations

Mina Arai-Okuda
Yusuke Murai
Makoto Nakamura
ResearchOpen Access14 Feb 2024
Scientific Reports

Volume: 14, P: 1-12
Hyperfructosemia in sleep disordered breathing: metabolome analysis of Nagahama study

Yoshinari Nakatsuka
Kimihiko Murase
Kazuo Chin
ResearchOpen Access05 Aug 2023
Scientific Reports

Volume: 13, P: 1-12
Blood mercury, lead, cadmium, manganese and selenium levels in pregnant women and their determinants: the Japan Environment and Children’s Study (JECS)

Shoji F. Nakayama
Miyuki Iwai-Shimada
Takahiko Katoh
ResearchOpen Access18 Apr 2019
Journal of Exposure Science & Environmental Epidemiology

Volume: 29, P: 633-647
Diversity in gut bacterial community of school-age children in Asia

Jiro Nakayama
Koichi Watanabe
Yuan-Kun Lee
ResearchOpen Access23 Feb 2015
Scientific Reports

Volume: 5, P: 1-11
Blood pressure during long-term cilostazol-based dual antiplatelet therapy after stroke: a post hoc analysis of the CSPS.com trial

Kazunori Toyoda
Masatoshi Koga
Hiroaki Tanaka
ResearchOpen Access09 Jul 2024
Hypertension Research

Volume: 47, P: 2238-2249
Correction: Comparison of two families with and without ataxia harboring novel variants in PRKCG

Yui Tada
Kodai Kume
Hideshi Kawakami
Amendments and Corrections07 Jul 2022
Journal of Human Genetics

Volume: 67, P: 621
Combined effects of blood pressure and glucose status on the risk of chronic kidney disease

This large-scale longitudinal cohort study showed high BP and diabetes synergistically increased the risk of CKD in individuals without AHT. Strict BP management may play an important role in the early prevention of CKD in individuals with worse glucose status within the young and middle-aged population.

Maya Toyama
Michihiro Satoh
Hirohito Metoki
ResearchOpen Access26 Apr 2024
Hypertension Research

Volume: 47, P: 1831-1841
The effects of bathing in neutral bicarbonate ion water

Tomoe Yamazaki
Ryoko Ushikoshi-Nakayama
Ichiro Saito
ResearchOpen Access08 Nov 2021
Scientific Reports

Volume: 11, P: 1-12
Mitochondrial fission inhibition protects against hypertension induced by angiotensin II

Kyle J. Preston
Tatsuo Kawai
Satoru Eguchi
Research21 Feb 2024
Hypertension Research

Volume: 47, P: 1338-1349
Seasonal variation in nocturnal home blood pressure fall: the Nagahama study

Yasuharu Tabara
Takeshi Matsumoto
Fumihiko Matsuda
Research30 Jan 2018
Hypertension Research

Volume: 41, P: 198-208
Utility of a rapid assay for prostaglandin E-major urinary metabolite as a biomarker in pediatric ulcerative colitis

Shin-ichiro Hagiwara
Naoki Abe
Yuri Etani
ResearchOpen Access19 Jun 2023
Scientific Reports

Volume: 13, P: 1-10
Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma

Akihiro Kitagawa
Tsuyoshi Osawa
Koshi Mimori
ResearchOpen Access19 Apr 2023
British Journal of Cancer

Volume: 128, P: 2206-2217
Cross-classification by systolic and diastolic blood pressure levels and chronic kidney disease, proteinuria, or kidney function decline

Tsukasa Suenaga
Michihiro Satoh
Hirohito Metoki
Research30 Mar 2023
Hypertension Research

Volume: 46, P: 1860-1869
Perioperative Adriamycin plus ifosfamide vs. gemcitabine plus docetaxel for high-risk soft tissue sarcomas: randomised, phase II/III study JCOG1306

Kazuhiro Tanaka
Ryunosuke Machida
Yukihide Iwamoto
ResearchOpen Access23 Jul 2022
British Journal of Cancer

Volume: 127, P: 1487-1496
The prevalence and clinical features of MYO7A-related hearing loss including DFNA11, DFNB2 and USH1B

Kizuki Watanabe
Shin-ya Nishio
Shunsuke Kondo
ResearchOpen Access09 Apr 2024
Scientific Reports

Volume: 14, P: 1-19
Predictors of hypoxemia in type-B acute aortic syndrome: a retrospective study

Yudai Tamura
Yuichi Tamura
Tadashi Sawamura
ResearchOpen Access03 Dec 2021
Scientific Reports

Volume: 11, P: 1-9
Oral administration of Lactobacillus gasseri SBT2055 is effective in preventing Porphyromonas gingivalis-accelerated periodontal disease

R. Kobayashi
T. Kobayashi
T. Kurita-Ochiai
ResearchOpen Access03 Apr 2017
Scientific Reports

Volume: 7, P: 1-10
Cyanidioschyzon merolae aurora kinase phosphorylates evolutionarily conserved sites on its target to regulate mitochondrial division

Kato et al. show that red alga Cyanidioschyzon merolae aurora kinase CmAUR regulates mitochondrial division by phosphorylating mitochondrial division ring components. Depletion of the evolutionarily conserved phosphorylation site on CmAUR targets causes defective mitochondrial divisions, suggesting an ancient origin of this regulation during endosymbiosis.

Shoichi Kato
Erika Okamura
Sachihiro Matsunaga
ResearchOpen Access20 Dec 2019
Communications Biology

Volume: 2, P: 1-9
Upregulated expression of FGF13/FHF2 mediates resistance to platinum drugs in cervical cancer cells

Tomoko Okada
Kazuhiro Murata
Toru Imamura
ResearchOpen Access11 Oct 2013
Scientific Reports

Volume: 3, P: 1-8
A two-component system regulates gene expression of the type IX secretion component proteins via an ECF sigma factor

Tomoko Kadowaki
Hideharu Yukitake
Koji Nakayama
ResearchOpen Access21 Mar 2016
Scientific Reports

Volume: 6, P: 1-12
Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13–p12 in Japanese

Hajime Nawata
Senji Shirasawa
Takehiko Sasazuki
Research01 Nov 2004
Journal of Human Genetics

Volume: 49, P: 629-634
A Promoter Haplotype of the Inositol Monophosphatase 2 Gene (IMPA2) at 18p11.2 Confers a Possible Risk for Bipolar Disorder by Enhancing Transcription

Tetsuo Ohnishi
Kazuo Yamada
Takeo Yoshikawa
Research24 Jan 2007
Neuropsychopharmacology

Volume: 32, P: 1727-1737
Prognostic importance of CDK4/6-specific activity as a predictive marker for recurrence in patients with endometrial cancer, with or without adjuvant chemotherapy

Yuji Ikeda
Katsutoshi Oda
Tomoyuki Fujii
ResearchOpen Access10 Nov 2015
British Journal of Cancer

Volume: 113, P: 1477-1483
Direct visualization of virus removal process in hollow fiber membrane using an optical microscope

Miku Ayano
Yoshiyuki Sawamura
Takayuki Nishizaka
ResearchOpen Access13 Jan 2021
Scientific Reports

Volume: 11, P: 1-9
Author Correction: Diversity in gut bacterial community of school-age children in Asia

Jiro Nakayama
Koichi Watanabe
Yuan-Kun Lee
Amendments and CorrectionsOpen Access25 Apr 2019
Scientific Reports

Volume: 9, P: 1
Single-molecule pull-out manipulation of the shaft of the rotary motor F₁-ATPase

Tatsuya M. Naito
Tomoko Masaike
Takayuki Nishizaka
ResearchOpen Access15 May 2019
Scientific Reports

Volume: 9, P: 1-9
Generation of PLASE score for patent ductus arteriosus using the PLASE study database

Satoshi Masutani
Tetsuya Isayama
Shin Kato
ResearchOpen Access08 Feb 2025
Pediatric Research

Volume: 98, P: 152-160
Anemia in Patients with Severe Aortic Stenosis

Kazuya Nagao
Tomohiko Taniguchi
Mitsuru Kitano
ResearchOpen Access13 Feb 2019
Scientific Reports

Volume: 9, P: 1-11

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