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Showing 1–50 of 54 results

Advanced filters: Author: W R Bijlsma Clear advanced filters

Geographic varation in G6pd and Pgd allele frequencies in Drosophila melanogaster

J G Oakeshott
G K Chambers
D A Willcocks
Research01 Feb 1983
Heredity

Volume: 50, P: 67-72
Interaction between the Adh and αGpdh loci in Drosophila melanogaster: adult survival at high temperature

L Oudman
W van Delden
R Bijlsma
Research01 Apr 1992
Heredity

Volume: 68, P: 289-297
Evidence for an ependymoma tumour suppressor gene in chromosome region 22pter–22q11.2

T J M Hulsebos
N T Oskam
B C Hamel
ResearchOpen Access12 Nov 1999
British Journal of Cancer

Volume: 81, P: 1150-1154
Polymorphism at the Adh and αGpdh loci in Drosophila melanogaster: effects of rearing temperature on developmental rate, body weight, and some biochemical parameters

L Oudman
W van Delden
R Bijlsma
Research01 Aug 1991
Heredity

Volume: 67, P: 103-115
Intra- and Interpopulation Selection concerning the Alcohol Dehydrogenase Locus in Drosophila melanogaster

E. BIJLSMA-MEELES
W. VAN DELDEN
Research08 Feb 1974
Nature

Volume: 247, P: 369-371
Structure and amount of genetic variation at minisatellite loci within the subspecies complex of Phoca vitulina (the harbour seal)

A L Kappe
R Bijlsma
L van de Zande
Research01 May 1997
Heredity

Volume: 78, P: 457-463
Ethanol tolerance and the Adh polymorphism in a natural population of Drosophila melanogaster

JOHN A. MCKENZIE
STEPHEN W. MCKECHNIE
Research02 Mar 1978
Nature

Volume: 272, P: 75-76
Protein polymorphism and the rate of loss of duplicate gene expression

FRED W. ALLENDORF
Research02 Mar 1978
Nature

Volume: 272, P: 76-78
The significance of genetic erosion in the process of extinction. I. Genetic differentiation in Salvia pratensis and Scabiosa columbaria in relation to population size

R van Treuren
R Bijlsma
N J Ouborg
Research01 Apr 1991
Heredity

Volume: 66, P: 181-189
Population genomics of Group B Streptococcus reveals the genetics of neonatal disease onset and meningeal invasion

Group B Streptococcus (GBS) causes neonatal disease and mortality worldwide. Here, the authors use genome-wide association analyses to identify bacterial genetic signatures associated with disease onset time and meningeal tissue infection in acute invasive neonatal GBS disease.

Chrispin Chaguza
Dorota Jamrozy
Stephen D. Bentley
ResearchOpen Access21 Jul 2022
Nature Communications

Volume: 13, P: 1-13
Localization of Haptoglobin and ABO

T. W. J. HUSTINX
J. B. BIJLSMA
L. E. NIJENHUIS
Research17 Jul 1965
Nature

Volume: 207, P: 327-328
Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders

Neurodevelopmental disorders (NDDs) are a heterogeneous group of diseases for which the genetic basis is still unknown in more than half of the cases. Here, the authors report a NDD associated with disruptive variants in the TANC2 gene and show that rols, the TANC2 homolog in flies, is required for synapse growth and function.

Hui Guo
Elisa Bettella
Evan E. Eichler
ResearchOpen Access15 Oct 2019
Nature Communications

Volume: 10, P: 1-17
Presentation and characterisation of the ALBA micro8 system for targeted hyperthermia in small animal research

J. A. Groen
R. Zweije
H. P. Kok
ResearchOpen Access29 Oct 2025
Scientific Reports

Volume: 15, P: 1-13
Molecular characterization of colorectal cancer related peritoneal metastatic disease

Colorectal cancer can lead to the development of peritoneal metastases, which are associated with worse disease outcome. Here, the authors characterize peritoneal metastases from 52 patients using RNA-seq and mutational sequencing and show a distinct molecular subtype.

Kristiaan J. Lenos
Sander Bach
Louis Vermeulen
ResearchOpen Access04 Aug 2022
Nature Communications

Volume: 13, P: 1-14
Bird tolerance to humans in open tropical ecosystems

The degree to which species tolerate human disturbance contributes to shape human-wildlife coexistence. Here, the authors identify key predictors of avian tolerance of humans across 842 bird species from open tropical ecosystems.

Peter Mikula
Oldřich Tomášek
Tomáš Albrecht
ResearchOpen Access20 Apr 2023
Nature Communications

Volume: 14, P: 1-10
The estimation of epistasis in components of fitness in experimental populations of Drosophila melanogaster I. A two-stage maximum likelihood model

A G Clark
M W Feldman
F B Christiansen
Research01 Jun 1981
Heredity

Volume: 46, P: 321-346
Current view of glucocorticoid co-therapy with DMARDs in rheumatoid arthritis

Glucocorticoids are widely used anti-inflammatory and immunosuppressive drugs for rheumatoid arthritis. This Review outlines the indications for and benefits of glucocorticoids as co-therapy with other DMARDs, describes the adverse effects that are predominantly associated with high-dose or long-term therapy, and considers the impact of patients' and doctors' perceptions of glucocorticoid therapy on prescribing and adherence to treatment.

Jos N. Hoes
Johannes W. G. Jacobs
Johannes W. J. Bijlsma
Reviews01 Dec 2010
Nature Reviews Rheumatology

Volume: 6, P: 693-702
Development of tolerance to ethanol in relation to the alcohol dehydrogenase locus in Drosophila melanogaster 1. Adult and egg-to-adult survival in relation to ADH activity

J W M Kerver
W van Delden
Research01 Dec 1985
Heredity

Volume: 55, P: 355-367
Genotypic-specific habitat selection: a new model and its application

Philip W Hedrick
Research01 Oct 1990
Heredity

Volume: 65, P: 145-149
CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

Individual SNPs have small effects on anthropometric traits, yet the impact of CNVs has remained largely unknown. Here, Kutalik and co-workers perform a large-scale genome-wide meta-analysis of structural variation and find rare CNVs associated with height, weight and BMI with large effect sizes.

Aurélien Macé
Marcus A. Tuke
Zoltán Kutalik
ResearchOpen Access29 Sept 2017
Nature Communications

Volume: 8, P: 1-11
The pluripotency factor NANOG contributes to mesenchymal plasticity and is predictive for outcome in esophageal adenocarcinoma

Van der Zalm et al. apply Ridge regression analysis to RNA-seq data from esophageal cancer samples to predict mesenchymal transitions occurring in patients. Expression of NANOG in pre-treatment biopsies is associated with poor response to neoadjuvant chemoradiation, recurrence, and median overall survival in patients with esophageal adenocarcinoma.

Amber P. van der Zalm
Mark P. G. Dings
Maarten F. Bijlsma
ResearchOpen Access17 May 2024
Communications Medicine

Volume: 4, P: 1-11
Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway

Wouter J de Jonge
Esmerij P van der Zanden
Guy E Boeckxstaens
Research17 Jul 2005
Nature Immunology

Volume: 6, P: 844-851
Antibodies to Human HSP60 in Patients with Juvenile Chronic Arthritis, Diabetes Mellitus, and Cystic Fibrosis

E R de Graeff-Meeder
G T Rijkers
B J M Zegers
Research01 Oct 1993
Pediatric Research

Volume: 34, P: 424-428
Book Reviews

Eviatar Nevo
John B Clegg
Douglas C Barker
Books & Arts01 Nov 1998
Heredity

Volume: 81, P: 591-597
Genetic polymorphism in a temporally varying environment: effects of delayed germination or diapause

Philip W Hedrick
Research01 Aug 1995
Heredity

Volume: 75, P: 164-170
Selection against Adh null alleles in Drosophila melanogaster

W van Delden
A Kamping
Research01 Oct 1988
Heredity

Volume: 61, P: 209-216
Unsupervised class discovery in pancreatic ductal adenocarcinoma reveals cell-intrinsic mesenchymal features and high concordance between existing classification systems

Frederike Dijk
Veronique L. Veenstra
Maarten F. Bijlsma
ResearchOpen Access15 Jan 2020
Scientific Reports

Volume: 10, P: 1-12
ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy

V. L. Veenstra
H. Damhofer
M. F. Bijlsma
ResearchOpen Access16 Nov 2018
Oncogenesis

Volume: 7, P: 1-11
Genetical variation for enzyme activity in a population of Drosophila Melanogaster

B W Barnes
A J Birley
Research01 Feb 1978
Heredity

Volume: 40, P: 51-57
Genetic variation in Phoca vitulina (the harbour seal) revealed by DNA fingerprinting and RAPDs

A L Kappe
L van de Zande
W van Delden
Research01 Jun 1995
Heredity

Volume: 74, P: 647-653
4q32–q35 and 6q16–q22 are valuable candidate regions for split hand/foot malformation

Dunja Niedrist
Iosif W Lurie
Albert Schinzel
Research18 Feb 2009
European Journal of Human Genetics

Volume: 17, P: 1086-1091
Within- and between-generation effects of temperature on early fecundity of Drosophila melanogaster

Raymond B Huey
Tamekia Wakefield
George W Gilchrist
Research01 Feb 1995
Heredity

Volume: 74, P: 216-223
Managing rheumatic and musculoskeletal diseases — past, present and future

The field of rheumatology has seen remarkable progress in the past 70 years. This Perspectives article provides a concise overview of developments in the diagnosis and management of musculoskeletal rheumatic diseases, and what the future of rheumatology might hold.

Gerd R. Burmester
Johannes W. J. Bijlsma
Iain B. McInnes
Reviews15 Jun 2017
Nature Reviews Rheumatology

Volume: 13, P: 443-448
Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells

Patricia D Pelton
Larry S Sherman
Nancy Ratner
Research29 Oct 1998
Oncogene

Volume: 17, P: 2195-2209
Long-term survival and transmission of INI1-mutation via nonpenetrant males in a family with rhabdoid tumour predisposition syndrome

A C J Ammerlaan
A Ararou
T J M Hulsebos
ResearchOpen Access18 Dec 2007
British Journal of Cancer

Volume: 98, P: 474-479
An investigation of inbreeding depression and purging in captive pedigreed populations

E H Boakes
J Wang
W Amos
Research20 Dec 2006
Heredity

Volume: 98, P: 172-182
A systematic review and meta-analysis of prognostic biomarkers in resectable esophageal adenocarcinomas

Aafke Creemers
Eva A. Ebbing
Hanneke W. M. van Laarhoven
ResearchOpen Access05 Sept 2018
Scientific Reports

Volume: 8, P: 1-11
Discordance in HER2 Status in Gastro-esophageal Adenocarcinomas: A Systematic Review and Meta-analysis

A. Creemers
E. ter Veer
H. W. M. van Laarhoven
ResearchOpen Access09 Jun 2017
Scientific Reports

Volume: 7, P: 1-10
Extreme migratory connectivity and apparent mirroring of non-breeding grounds conditions in a severely declining breeding population of an Afro-Palearctic migratory bird

Máire Kirkland
Nathaniel N. D. Annorbah
Chris M. Hewson
ResearchOpen Access26 Jan 2025
Scientific Reports

Volume: 15, P: 1-17
Partial support for the central–marginal hypothesis within a population: reduced genetic diversity but not increased differentiation at the range edge of an island endemic bird

K M Langin
T S Sillett
C K Ghalambor
Research22 Mar 2017
Heredity

Volume: 119, P: 8-15
Increasing incidence of group B streptococcus neonatal infections in the Netherlands is associated with clonal expansion of CC17 and CC23

Dorota Jamrozy
Merijn W. Bijlsma
Stephen D. Bentley
ResearchOpen Access12 Jun 2020
Scientific Reports

Volume: 10, P: 1-13
De novo loss-of-function mutations in WAC cause a recognizable intellectual disability syndrome and learning deficits in Drosophila

Dorien Lugtenberg
Margot R F Reijnders
Lisenka E L M Vissers
Research13 Jan 2016
European Journal of Human Genetics

Volume: 24, P: 1145-1153
The ARID1B spectrum in 143 patients: from nonsyndromic intellectual disability to Coffin–Siris syndrome

Pleuntje J. van der Sluijs
Sandra Jansen
Gijs W. E. Santen
ResearchOpen Access08 Nov 2018
Genetics in Medicine

Volume: 21, P: 1295-1307
KidneyNetwork: using kidney-derived gene expression data to predict and prioritize novel genes involved in kidney disease

Floranne Boulogne
Laura R. Claus
Albertien M. van Eerde
ResearchOpen Access20 Feb 2023
European Journal of Human Genetics

Volume: 31, P: 1300-1308
Incidence of primary malignant orbital tumours in the Netherlands

J H Koopman
M van der Heiden-van der Loo
W R Bijlsma
Research18 Feb 2011
Eye

Volume: 25, P: 461-465
Environmental effects on sex differences in the genetic load for adult lifespan in a seed-feeding beetle

C W Fox
R C Stillwell
Research01 Apr 2009
Heredity

Volume: 103, P: 62-72
Putting genome-wide sequencing in neonates into perspective

Pleuntje J. van der Sluijs
Emmelien Aten
Gijs W. E. Santen
Research05 Oct 2018
Genetics in Medicine

Volume: 21, P: 1074-1082
Functional and clinical studies reveal pathophysiological complexity of CLCN4-related neurodevelopmental condition

Elizabeth E. Palmer
Michael Pusch
Vera M. Kalscheuer
ResearchOpen Access16 Nov 2022
Molecular Psychiatry

Volume: 28, P: 668-697
Widening of the genetic and clinical spectrum of Lamb–Shaffer syndrome, a neurodevelopmental disorder due to SOX5 haploinsufficiency

Ash Zawerton
Cyril Mignot
Christel Depienne
Research03 Oct 2019
Genetics in Medicine

Volume: 22, P: 524-537
Correction: Putting genome-wide sequencing in neonates into perspective

Pleuntje J. van der Sluijs
Emmelien Aten
Gijs W. E. Santen
Amendments and Corrections21 Nov 2018
Genetics in Medicine

Volume: 21, P: 2159-2164

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