This study finds that inhibition of the hypothalamic melanocortin receptors increases the level of high-density lipoprotein HDL-C, a form of cholesterol, circulating in the blood stream. Uptake of HDL-C into the liver was slowed, as expression of one of the hepatic cholesterol receptors was downregulated.
- Diego Perez-Tilve
- Susanna M Hofmann
- Matthias H Tschöp