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Advanced filters: Author: Wenshu Zheng Clear advanced filters

Enhanced diagnosis of multi-drug-resistant microbes using group association modeling and machine learning

In this work, authors describe a Group Association Model (GAM) that detects genotype phenotype associations in microbial drug resistance; refined with the machine learning, it identifies features for predictive modelling, reducing cross-resistance artifacts and potentially improving treatment decisions.

Julian G. Saliba
Wenshu Zheng
Tony Ye Hu
ResearchOpen Access25 Mar 2025
Nature Communications

Volume: 16, P: 1-15
Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples

The optical detection of two virulence factors of Mycobacterium tuberculosis on extracellular vesicles in blood allowed for the diagnosis of tuberculosis in paediatric cases that were missed by clinical microbiological assays.

Wenshu Zheng
Sylvia M. LaCourse
Tony Y. Hu
ResearchOpen Access19 Aug 2022
Nature Biomedical Engineering

Volume: 6, P: 979-991
microRNA-137 promotes apoptosis in ovarian cancer cells via the regulation of XIAP

Xiaodi Li
Wei Chen
Songshan Jiang
ResearchOpen Access22 Nov 2016
British Journal of Cancer

Volume: 116, P: 66-76
Chimerically fused antigen rich of overlapped epitopes from latent membrane protein 2 (LMP2) of Epstein–Barr virus as a potential vaccine and diagnostic agent

Xiaoyun Lin
Shao Chen
Lifang Zhang
Research13 Apr 2015
Cellular & Molecular Immunology

Volume: 13, P: 492-501

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