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Showing 1–5 of 5 results
Advanced filters: Author: William Benman Clear advanced filters

  • The Melt (Membrane localization using temperature) protein translocates to the plasma membrane upon temperature shift. Melt variants with a range of switching temperatures enable straightforward thermogenetic control of diverse cellular processes.

    • William Benman
    • Zikang Huang
    • Lukasz J. Bugaj
    Research
    Nature Methods
    Volume: 22, P: 539-549

  • The BcLOV4 photoreceptor was used to generate single-component optogenetic signaling probes whose activation dynamics are dependent on light and temperature, allowing multiplexing of blue-light-sensitive tools in mammalian cells

    • William Benman
    • Erin E. Berlew
    • Lukasz J. Bugaj
    Research
    Nature Chemical Biology
    Volume: 18, P: 152-160

  • The availability of high performance recombinases with low basal activity and high dynamic range is limited. Here the authors present a library of over 20 orthogonal split recombinases that can be induced by small molecules, light and temperature in vivo.

    • Benjamin H. Weinberg
    • Jang Hwan Cho
    • Wilson W. Wong
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10

  • Controlled assembly of synthetic intracellular condensates from engineered disordered proteins enables control of cellular activities such as proliferation and division through recruitment, sequestration and insulation of endogenous client proteins.

    • Mikael V. Garabedian
    • Wentao Wang
    • Matthew C. Good
    Research
    Nature Chemical Biology
    Volume: 17, P: 998-1007