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Showing 1–3 of 3 results
Advanced filters: Author: Woo-Chang Chung Clear advanced filters
  • G-quadruplex (G4) structures are found in eukaryotic cell replication origins, but their role remains unclear. Here, the authors show that G4 in the cytomegalovirus replication origin is critical in recruiting viral replication factors and that G4-binding ligands inhibit viral factors’ G4 binding.

    • Daegyu Park
    • Woo-Chang Chung
    • Jin-Hyun Ahn
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15
  • Cytokines such as TNF and IFN-γ are important for immunity against hepatitis B virus (HBV). Here the authors show that interleukin-32 gamma (IL-32γ) acts downstream of TNF and IFN-γ as an intracellular effector, and that IL-32γ negatively regulates host factors contributing to HBV transcription to promote HBV clearance.

    • Doo Hyun Kim
    • Eun-Sook Park
    • Kyun-Hwan Kim
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15