Nature Search

Effect of high-dose N-acetylcysteine on exacerbations and lung function in patients with mild-to-moderate COPD: a double-blind, parallel group, multicentre randomised clinical trial

Evidence for the treatment of patients with mild-to-moderate COPD is limited. Here, the authors show that long-term treatment with high-dose N-acetylcysteine neither significantly reduced the annual rate of total exacerbations nor improve lung function in patients with mild-tomoderate COPD.

Yumin Zhou
Fan Wu
Li Chen
ResearchOpen Access30 Sept 2024
Nature Communications

Volume: 15, P: 1-11
A viral protein activates the MAPK pathway to promote viral infection by downregulating callose deposition in plants

MAPK cascades activate innate immunity to defend against various pathogens. Here the authors show that Nicotiana benthamiana NbMPK3/6 can phosphorylate the tomato chlorosis virus P7 protein leading to suppression of callose-dependent antiviral defence.

Lixiao Feng
Xiangwen Luo
Yong Liu
ResearchOpen Access04 Dec 2024
Nature Communications

Volume: 15, P: 1-18
Relocate 10 billion livestock to reduce harmful nitrogen pollution exposure for 90% of China’s population

Spatial planning and policy could guide China’s livestock sector towards reducing human exposure to ammonia—provided that 5–10 billion animals are relocated across the region.

Zhaohai Bai
Xiangwen Fan
Lin Ma
Research10 Feb 2022
Nature Food

Volume: 3, P: 152-160
Food and feed trade has greatly impacted global land and nitrogen use efficiencies over 1961–2017

Resource depletion and environmental impacts associated with food and feed imports and exports must be measured. This study maps and quantifies land and nitrogen losses from agricultural trade in more than 240 countries for the past six decades through an innovative trade optimality evaluation method.

Zhaohai Bai
Wenqi Ma
Lin Ma
Research14 Oct 2021
Nature Food

Volume: 2, P: 780-791
Dendrite initiation and propagation in lithium metal solid-state batteries

Analysis of dendrite initiation, owing to filling of pores with lithium by means of microcracks, and propagation, caused by wedge opening, shows that there are two separate processes during dendrite failure of lithium metal solid-state batteries.

Ziyang Ning
Guanchen Li
Peter G. Bruce
Research07 Jun 2023
Nature

Volume: 618, P: 287-293
Co-benefits of transport demand reductions from compact urban development in Chinese cities

Rapid urbanization poses several challenges but can offer opportunities for cities to become more sustainable by, for example, reducing transport demand and its associated emissions. This study shows how this can be achieved and quantifies the co-benefits for climate, energy use, air quality and human health.

Xiangwen Fu
Jing Cheng
Denise L. Mauzerall
Research08 Feb 2024
Nature Sustainability

Volume: 7, P: 294-304
Multiple independent losses of the biosynthetic pathway for two tropane alkaloids in the Solanaceae family

Hyoscyamine and scopolamine (HS) are two tropane alkaloids with medicinal significance produced by distantly related lineages in the Solanaceae family. Here, the authors assemble the genome of three HS-producing and one non-HS-producing species within Solanaceae, and reveal the evolution of the biosynthetic pathway.

Jiao Yang
Ying Wu
Jianquan Liu
ResearchOpen Access20 Dec 2023
Nature Communications

Volume: 14, P: 1-18
High-energy all-solid-state lithium batteries enabled by Co-free LiNiO₂ cathodes with robust outside-in structures

In-depth mechanistic insights inform the fabrication of an all-solid-state, Co-free lithium battery with good performance and cyclability.

Longlong Wang
Ayan Mukherjee
Malachi Noked
Research05 Oct 2023
Nature Nanotechnology

Volume: 19, P: 208-218
Ultrathin MoS₂ Nanosheets with Superior Extreme Pressure Property as Boundary Lubricants

Zhe Chen
Xiangwen Liu
Jianbin Luo
ResearchOpen Access07 Aug 2015
Scientific Reports

Volume: 5, P: 1-7
Reln-Dab1 pathway mitigates retinal ganglion cell apoptosis in retinal ischemia-reperfusion injury

Ning Xu
Zongyuan Li
Liqiang Wang
ResearchOpen Access29 May 2025
Cell Death & Disease

Volume: 16, P: 1-13
Cloning and characterization of a pyrethroid pesticide decomposing esterase gene, Est3385, from Rhodopseudomonas palustris PSB-S

Xiangwen Luo
Deyong Zhang
Yong Liu
ResearchOpen Access09 May 2018
Scientific Reports

Volume: 8, P: 1-8
Carbene-catalyzed asymmetric Friedel–Crafts alkylation-annulation sequence and rapid synthesis of indole-fused polycyclic alkaloids

Indole-fused polycyclic alkaloids are present in numerous bioactive natural products. Here an enantioselective N-heterocyclic carbene-catalysed Friedel–Crafts alkylation/annulation cascade using acyl azolium salts as the electrophile provides access to these products with high stereoselectivity.

Muhammad Anwar
Shuang Yang
Xinqiang Fang
ResearchOpen Access24 Jul 2019
Communications Chemistry

Volume: 2, P: 1-9
Manipulating spin polarization of titanium dioxide for efficient photocatalysis

Photocatalyst activity depends significantly on the material’s electronic structures. Here, authors manipulate the electron spin polarization of TiO₂ by tuning the concentration of Ti vacancies and show improved photocatalytic activities.

Lun Pan
Minhua Ai
Wenbo Mi
ResearchOpen Access21 Jan 2020
Nature Communications

Volume: 11, P: 1-9
One-Pot Protocol for Bimetallic Pt/Cu Hexapod Concave Nanocrystals with Enhanced Electrocatalytic Activity

Xiangwen Liu
Weiyang Wang
Yadong Li
ResearchOpen Access08 Mar 2013
Scientific Reports

Volume: 3, P: 1-5
Climate-driven increase of natural wetland methane emissions offset by human-induced wetland reduction in China over the past three decades

Qiuan Zhu
Changhui Peng
Jin-Sheng He
ResearchOpen Access28 Nov 2016
Scientific Reports

Volume: 6, P: 1-7
Image segmentation and coverage estimation of deep-sea polymetallic nodules based on lightweight deep learning model

Yue Hao
Shijuan Yan
Dewen Du
ResearchOpen Access24 Mar 2025
Scientific Reports

Volume: 15, P: 1-21
Identification of a novel disulfidptosis-related gene signature in osteoarthritis using bioinformatics analysis and experimental validation

Mingjie Wei
Xiangwen Shi
Yongqing Xu
ResearchOpen Access08 Jan 2025
Scientific Reports

Volume: 15, P: 1-19
Prompt engineering in consistency and reliability with the evidence-based guideline for LLMs

Li Wang
Xi Chen
Jian Li
ResearchOpen Access20 Feb 2024
npj Digital Medicine

Volume: 7, P: 1-9
Analysis of tire contact stresses and asphalt pavement rutting under gradient temperature and typical driving conditions

Minrui Guo
Pei Liu
Haitao Ge
ResearchOpen Access23 Jan 2025
Scientific Reports

Volume: 15, P: 1-18
A potential coagulation-related diagnostic model associated with immune infiltration for acute myocardial infarction

Guoqing Liu
Wang Liao
Lang Li
Research08 Oct 2024
Genes & Immunity

Volume: 25, P: 471-482
Variation in wood physical properties and effects of climate for different geographic sources of Chinese fir in subtropical area of China

Ren You
Ninghua Zhu
Fei Liu
ResearchOpen Access25 Feb 2021
Scientific Reports

Volume: 11, P: 1-11
Bph32, a novel gene encoding an unknown SCR domain-containing protein, confers resistance against the brown planthopper in rice

Juansheng Ren
Fangyuan Gao
Guangjun Ren
ResearchOpen Access23 Nov 2016
Scientific Reports

Volume: 6, P: 1-14
Probiotics and prebiotics: new treatment strategies for oral potentially malignant disorders and gastrointestinal precancerous lesions

Zhuwei Huang
Jiaye Zhu
Xiang Wang
ReviewsOpen Access08 Apr 2025
npj Biofilms and Microbiomes

Volume: 11, P: 1-15
Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence

Yan Sun
Suhua Chang
Jie Shi
Research28 Aug 2019
Molecular Psychiatry

Volume: 26, P: 1152-1161
RNF8 enhances the sensitivity of PD-L1 inhibitor against melanoma through ubiquitination of galectin-3 in stroma

Yanan Guo
Rong Shen
Degui Wang
ResearchOpen Access30 Jun 2023
Cell Death Discovery

Volume: 9, P: 1-14
Transcriptome and genome sequencing elucidates the molecular basis for the high yield and good quality of the hybrid rice variety Chuanyou6203

Juansheng Ren
Fan Zhang
Guangjun Ren
ResearchOpen Access17 Nov 2020
Scientific Reports

Volume: 10, P: 1-15
The transcription factor FoxM1 activates Nurr1 to promote intestinal regeneration after ischemia/reperfusion injury

Guo Zu
Jing Guo
Xiangwen Zhang
ResearchOpen Access08 Nov 2019
Experimental & Molecular Medicine

Volume: 51, P: 1-12
Tree functional types simplify forest carbon stock estimates induced by carbon concentration variations among species in a subtropical area

Huili Wu
Wenhua Xiang
Xiangwen Deng
ResearchOpen Access10 Jul 2017
Scientific Reports

Volume: 7, P: 1-11

Search

Effect of high-dose N-acetylcysteine on exacerbations and lung function in patients with mild-to-moderate COPD: a double-blind, parallel group, multicentre randomised clinical trial

A viral protein activates the MAPK pathway to promote viral infection by downregulating callose deposition in plants

Relocate 10 billion livestock to reduce harmful nitrogen pollution exposure for 90% of China’s population

Food and feed trade has greatly impacted global land and nitrogen use efficiencies over 1961–2017

Dendrite initiation and propagation in lithium metal solid-state batteries

Co-benefits of transport demand reductions from compact urban development in Chinese cities

Multiple independent losses of the biosynthetic pathway for two tropane alkaloids in the Solanaceae family

High-energy all-solid-state lithium batteries enabled by Co-free LiNiO₂ cathodes with robust outside-in structures

Ultrathin MoS₂ Nanosheets with Superior Extreme Pressure Property as Boundary Lubricants

Reln-Dab1 pathway mitigates retinal ganglion cell apoptosis in retinal ischemia-reperfusion injury

Cloning and characterization of a pyrethroid pesticide decomposing esterase gene, Est3385, from Rhodopseudomonas palustris PSB-S

Carbene-catalyzed asymmetric Friedel–Crafts alkylation-annulation sequence and rapid synthesis of indole-fused polycyclic alkaloids

Manipulating spin polarization of titanium dioxide for efficient photocatalysis

One-Pot Protocol for Bimetallic Pt/Cu Hexapod Concave Nanocrystals with Enhanced Electrocatalytic Activity

Climate-driven increase of natural wetland methane emissions offset by human-induced wetland reduction in China over the past three decades

Image segmentation and coverage estimation of deep-sea polymetallic nodules based on lightweight deep learning model

Identification of a novel disulfidptosis-related gene signature in osteoarthritis using bioinformatics analysis and experimental validation

Prompt engineering in consistency and reliability with the evidence-based guideline for LLMs

Analysis of tire contact stresses and asphalt pavement rutting under gradient temperature and typical driving conditions

A potential coagulation-related diagnostic model associated with immune infiltration for acute myocardial infarction

Variation in wood physical properties and effects of climate for different geographic sources of Chinese fir in subtropical area of China

Bph32, a novel gene encoding an unknown SCR domain-containing protein, confers resistance against the brown planthopper in rice

Probiotics and prebiotics: new treatment strategies for oral potentially malignant disorders and gastrointestinal precancerous lesions

Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence

RNF8 enhances the sensitivity of PD-L1 inhibitor against melanoma through ubiquitination of galectin-3 in stroma

Transcriptome and genome sequencing elucidates the molecular basis for the high yield and good quality of the hybrid rice variety Chuanyou6203

The transcription factor FoxM1 activates Nurr1 to promote intestinal regeneration after ischemia/reperfusion injury

Tree functional types simplify forest carbon stock estimates induced by carbon concentration variations among species in a subtropical area

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