Nature Search

Polygenic prediction of body mass index and obesity through the life course and across ancestries

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Roelof A. J. Smit
Kaitlin H. Wade
Ruth J. F. Loos
ResearchOpen Access21 Jul 2025
Nature Medicine

Volume: 31, P: 3151-3168
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

A meta-analysis of genome-wide association studies of type 2 diabetes (T2D) identifies more than 600 T2D-associated loci; integrating physiological trait and single-cell chromatin accessibility data at these loci sheds light on heterogeneity within the T2D phenotype.

Ken Suzuki
Konstantinos Hatzikotoulas
Eleftheria Zeggini
ResearchOpen Access19 Feb 2024
Nature

Volume: 627, P: 347-357
Correction: Author Correction: Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis

Xianbo Zuo
Liangdan Sun
Xuejun Zhang
Amendments and CorrectionsOpen Access13 Mar 2018
Nature Communications

Volume: 9, P: 1
A saturated map of common genetic variants associated with human height

A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

Loïc Yengo
Sailaja Vedantam
Joel N. Hirschhorn
ResearchOpen Access12 Oct 2022
Nature

Volume: 610, P: 704-712
The power of genetic diversity in genome-wide association studies of lipids

A genome-wide association meta-analysis study of blood lipid levels in roughly 1.6 million individuals demonstrates the gain of power attained when diverse ancestries are included to improve fine-mapping and polygenic score generation, with gains in locus discovery related to sample size.

Sarah E. Graham
Shoa L. Clarke
Cristen J. Willer
Research09 Dec 2021
Nature

Volume: 600, P: 675-679
Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis

Psoriasis is a chronic inflammatory disease affecting up to 3% of the population. Here, Zuo et al.perform exome array analysis, identify single-nucleotide polymorphisms at 15 new loci, implicating several biological pathways in psoriasis risk and disease heritability.

Xianbo Zuo
Liangdan Sun
Xuejun Zhang
ResearchOpen Access09 Apr 2015
Nature Communications

Volume: 6, P: 1-7
Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Genome-wide association analyses of two oral glucose tolerance test-derived measures of postprandial insulin resistance discover ten new loci. Functional characterization identifies nine candidate genes implicated in the regulation of GLUT4.

Alice Williamson
Dougall M. Norris
Claudia Langenberg
Research08 Jun 2023
Nature Genetics

Volume: 55, P: 973-983
Deep sequencing of the MHC region in the Chinese population contributes to studies of complex disease

Xuejun Zhang, Jun Wang, Liangdan Sun, Lennart Hammarström and colleagues sequence the MHC region in 20,635 Han Chinese individuals. Their Han-MHC database allows identification of new susceptibility loci for psoriasis and could serve as a tool for investigating the role of the MHC region in other complex diseases.

Fusheng Zhou
Hongzhi Cao
Xuejun Zhang
Research23 May 2016
Nature Genetics

Volume: 48, P: 740-746
Diffusion-free Grotthuss topochemistry for high-rate and long-life proton batteries

This Article presents a battery with protons as the charge carrier, as opposed to Li-ion batteries, which rely on the transport of Li-ions. Protons are conducted by means of the Grotthuss mechanism in a hydrated Prussian blue analogue electrode, offering potential for ultrafast rate and long-life batteries.

Xianyong Wu
Jessica J. Hong
Xiulei Ji
Research28 Jan 2019
Nature Energy

Volume: 4, P: 123-130
Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups

The presentation of systemic lupus erythematosus has been known to differ by ancestry, but the underlying genetic factors remain unclear. Here, the authors report ancestry-specific susceptibility loci and better risk prediction when using data from matched ancestral groups.

Yong-Fei Wang
Yan Zhang
Wanling Yang
ResearchOpen Access03 Feb 2021
Nature Communications

Volume: 12, P: 1-13
Functional and structural brain remodeling in patients with degenerative cervical myelopathy following cervical decompression surgery

Xie, Ni et al. employ advanced magnetic resonance imaging (MRI) techniques to explore preoperative and postoperative cerebral alterations in patients with degenerative cervical myelopathy (DCM). Their findings suggest that brain function restoration relies more on neural network compensation than on structural repair alone.

Bingyong Xie
Haoyu Ni
Fulong Dong
ResearchOpen Access22 May 2025
Communications Medicine

Volume: 5, P: 1-13
Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification

de Vries, Conomos, Singh and Nicholson et al. identify two additional loci associated with coronary artery calcification (ARSE and MMP16) via a genome-wide association study in 22,400 participants from multiple ancestral groups and prove that ARSE is a mediator of vascular smooth muscle cell calcification and phenotype switching.

Paul S. de Vries
Matthew P. Conomos
Rajeev Malhotra
Research04 Dec 2023
Nature Cardiovascular Research

Volume: 2, P: 1159-1172
A low cost, all-organic Na-ion Battery Based on Polymeric Cathode and Anode

Wenwen Deng
Xinmiao Liang
Hanxi Yang
ResearchOpen Access16 Sept 2013
Scientific Reports

Volume: 3, P: 1-6
Reversible intercalation of methyl viologen as a dicationic charge carrier in aqueous batteries

Rechargeable batteries are governed by reversible intercalation reactions. Here the authors expand the intercalation chemistry to include methyl viologen as a large dicationic charge carrier in aqueous batteries. The bonding between guest and aromatic host is not pure ionic but shows strong covalent character.

Zhixuan Wei
Woochul Shin
Xiulei Ji
ResearchOpen Access19 Jul 2019
Nature Communications

Volume: 10, P: 1-10
Author Correction: The power of genetic diversity in genome-wide association studies of lipids

Sarah E. Graham
Shoa L. Clarke
Cristen J. Willer
Amendments and Corrections26 May 2023
Nature

Volume: 618, P: E19-E20
Aqueous batteries get energetic

Aqueous batteries hold promise for large-scale energy storage, but are often maligned because of their low energy densities. Now, a demonstration of halogen conversion–intercalation chemistry inside graphite has blazed a trail for high-energy aqueous batteries.

Xianyong Wu
Xiulei Ji
News & Views22 Jul 2019
Nature Chemistry

Volume: 11, P: 680-681
Theory and application of robust linear phase-shift algorithm for phase-shift deflectometry method

Song Yang
Xianyong Zhu
Zheyuan Wang
ResearchOpen Access08 Aug 2024
Scientific Reports

Volume: 14, P: 1-21
A large-scale screen for coding variants predisposing to psoriasis

Xuejun Zhang, Jun Wang and colleagues report the application of exome sequencing to a large collection of psoriasis cases and controls. They identify seven common and low-frequency nonsynonymous variants within known psoriasis susceptibility genes that are associated with psoriasis risk.

Huayang Tang
Xin Jin
Xuejun Zhang
Research10 Nov 2013
Nature Genetics

Volume: 46, P: 45-50
Study on the characteristics of future precipitation in response to external changes over arid and humid basins

Lianqing Xue
Boli Zhu
Guang Yang
ResearchOpen Access09 Nov 2017
Scientific Reports

Volume: 7, P: 1-13
RETRACTED ARTICLE: Simulation and spatiotemporal pattern of air temperature and precipitation in Eastern Central Asia using RegCM

Xianyong Meng
Aihua Long
Xiaonan Ji
ResearchOpen Access26 Feb 2018
Scientific Reports

Volume: 8, P: 1-10
Retraction Note: Simulation and spatiotemporal pattern of air temperature and precipitation in Eastern Central Asia using RegCM

Xianyong Meng
Aihua Long
Xiaonan Ji
Amendments and CorrectionsOpen Access18 Sept 2019
Scientific Reports

Volume: 9, P: 1
An improved calibration and uncertainty analysis approach using a multicriteria sequential algorithm for hydrological modeling

Hongjing Wu
Bing Chen
Baiyu Zhang
ResearchOpen Access20 Aug 2021
Scientific Reports

Volume: 11, P: 1-14
Efficiency and stability enhancement of perovskite solar cells by introducing CsPbI₃ quantum dots as an interface engineering layer

Due to the matching energy level of CsPbI₃ quantum dots and perovskite layer, the efficiency of perovskite solar cells was substantially enhanced from 15.17% to 18.56% by introducing CsPbI₃ quantum dots as interface engineering layer. Moreover, perovskite solar cells with CsPbI₃ QDs maintained 82% of its initial performance for 30 days at over 30% RH without any encapsulation.

Chang Liu
Manman Hu
Chun Cheng
ResearchOpen Access18 Jun 2018
NPG Asia Materials

Volume: 10, P: 552-561
Investigating spatiotemporal changes of the land-surface processes in Xinjiang using high-resolution CLM3.5 and CLDAS: Soil temperature

Xianyong Meng
Hao Wang
Xiaonan Ji
ResearchOpen Access16 Oct 2017
Scientific Reports

Volume: 7, P: 1-14
East Asian summer monsoon precipitation variability since the last deglaciation

Fahu Chen
Qinghai Xu
Zhiguo Rao
ResearchOpen Access18 Jun 2015
Scientific Reports

Volume: 5, P: 1-11

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