An array-based system for cancer cell sensing has been developed by using a ‘chemical nose/tongue’ approach that exploits subtle changes in the physicochemical nature of different cell surfaces. This electrochemical sensing array has ultrahigh sensitivity, which reaches low detection limit (about 1 cell) for the detection of single-cell type and can discern different cell types at level as low as 100 cells with high accuracy, such as (i) different cell types; (ii) cancerous, multidrug-resistant cancerous and metastatic human breast cells; (iii) artificial circulating tumor cells (CTCs).
- Li Wu
- Haiwei Ji
- Xiaogang Qu
