Nature Search

Direct and efficient synthesis of nucleosides through the ortho-(tert-butylethynyl)phenyl thioglycosides (BEPTs) protocol

Efficient chemical synthesis of nucleoside is challenging due to the low reactivity of nucleobases acceptors. Herein, the authors report a protocol for nucleoside synthesis with glycosyl o-(tert-butylethynyl)phenyl thioglycosides as donors.

Hui Liu
Ming-Yang Wang
Jian-Song Sun
ResearchOpen Access02 Oct 2025
Nature Communications

Volume: 16, P: 1-14
Extracellular vesicles from antler blastema progenitor cells reverse bone loss and mitigate aging-related phenotypes in mice and macaques

Inspired by the regenerative capacity of deer antlers, Hao and colleagues report that antler blastema progenitor cell-derived extracellular vesicle treatment counteracts bone loss and epigenetic aging and is neuroprotective in mice and macaques.

Yiming Hao
Beibei Yu
Jinghui Huang
ResearchOpen Access14 Jul 2025
Nature Aging

Volume: 5, P: 1790-1809
A nonvolatile magnon field effect transistor at room temperature

Searching non-charge-based devices is crucial for sustainable information processing. Here, the authors make a nonvolatile magnon field effect transistor at room temperature, enabling efficient magnon transport control via the gate voltage pulses.

Jun Cheng
Rui Yu
Haifeng Ding
ResearchOpen Access29 Oct 2024
Nature Communications

Volume: 15, P: 1-8
Exploring single-cell data with deep multitasking neural networks

SAUCIE, a deep learning platform to analyze single-cell data across samples and platforms, allows information to be obtained from the internal layers of the network, which provides additional mechanistic understanding that can be used to further tune data analysis.

Matthew Amodio
David van Dijk
Smita Krishnaswamy
Research07 Oct 2019
Nature Methods

Volume: 16, P: 1139-1145
A Gremlin 1-expressing splenic niche cell population restrains chronic myeloid leukemia by antagonizing the BMP pathway

Zhu and colleagues show that a subpopulation of spleen-derived fibroblasts secrete Gremlin 1, which suppresses chronic myeloid leukemia progression by inducing leukemia stem cell apoptosis through the BMP signaling pathway.

Jinming Wang
Penghui Xu
Helen He Zhu
Research17 Mar 2025
Nature Cancer

Volume: 6, P: 666-681
Kinetic drop friction

Sliding of drops over solid surface is a common phenomenon, but it remains impossible to predict the sliding velocity due to numerous dissipation channels causing drop friction. Li et al. show that dynamic wetting is determined by a dimensionless friction coefficient, which is a material parameter.

Xiaomei Li
Francisco Bodziony
Hans-Jürgen Butt
ResearchOpen Access29 Jul 2023
Nature Communications

Volume: 14, P: 1-10
Accelerated discovery of superoxide-dismutase nanozymes via high-throughput computational screening

A general predicting theory for superoxide-dismutase mimicking nanomaterials is currently lacking. The present manuscript reports a density functional theory study on the superoxides dismutase-like activity of nanomaterials based on their electronic band structures and surface adsorption energies.

Zhenzhen Wang
Jiangjiexing Wu
Yuliang Zhao
ResearchOpen Access25 Nov 2021
Nature Communications

Volume: 12, P: 1-11
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23

Jing Wang, Fengchun Zhang and colleagues report the results of a genome-wide association study of primary Sjögren's syndrome, a common autoimmune disease. They confirm associations in the STAT4, TNFAIP3 and HLA regions and identify a new susceptibility locus in the GTF2I region at 7q11.23.

Yongzhe Li
Kunlin Zhang
Fengchun Zhang
Research06 Oct 2013
Nature Genetics

Volume: 45, P: 1361-1365
Prospective prenatal cell-free DNA screening for genetic conditions of heterogenous etiologies

In a large prospective cohort of 1,090 pregnant women with a high risk of fetal genetic diseases, a cell-free DNA screening identified cases of aneuploidies, microdeletions and monogenic variants with high accuracy in concordance to standard diagnostic tests

Jinglan Zhang
Yanting Wu
Hefeng Huang
Research22 Jan 2024
Nature Medicine

Volume: 30, P: 470-479
Leucine aminopeptidase1 controls egg deposition and hatchability in male Aedes aegypti mosquitoes

Aedes aegypti transmit several arboviruses and control of the mosquito populations could be beneficial. Here the authors show that deletion of leucine aminopeptidase1 (LAP1) results in mitochondrial defects and abnormal autophagy in sperm, reducing fertility and fecundity of females. LAP1^−/− males show no obvious defects in longevity and mating fitness.

Xiaomei Sun
Xueli Wang
Zhen Zou
ResearchOpen Access02 Jan 2024
Nature Communications

Volume: 15, P: 1-15
A cross-sectional epidemiological study of non-suicidal self-injury prevalence in Chinese psychiatric patients

In the broader literature and across country contexts, higher levels of non-suicidal self-injury in adolescents and young adults have been reported. These data are a rare, robust and valuable contribution in documenting differences in non-suicidal self-injury in a large, nationally representative sample in China where the participants were diagnosed with Diagnostic and Statistical Manual of Mental Disorders, fifth edition criteria.

Pei Zhang
Lichen Ouyang
Chun Wang
Research18 Apr 2023
Nature Mental Health

Volume: 1, P: 266-272
Confining donor conformation distributions for efficient thermally activated delayed fluorescence with fast spin-flipping

The distribution of dihedral angles in film state has significant influence on excited state lifetimes of thermally activated delayed fluorescence emitters. Here authors report conformation distribution confinement strategy to achieve fast spin-flipping for efficient organic light-emitting diodes.

Weidong Qiu
Denghui Liu
Shi-Jian Su
ResearchOpen Access04 May 2023
Nature Communications

Volume: 14, P: 1-12
Osmosensor-mediated control of Ca²⁺ spiking in pollen germination

Screening in Escherichia coli and biochemical experiments show that in Arabidopsis thaliana, OSCA2.1 and OSCA2.2 function as plant sensors of hypo-osmolarity, utilize Ca²⁺ oscillations as second messengers and have crucial roles in pollen germination.

Songyu Pei
Qi Tao
Fang Yuan
ResearchOpen Access22 May 2024
Nature

Volume: 629, P: 1118-1125
Temperature-related mortality in China from specific injury

Injury poses heavy burden on public health, but little evidence on the potential role of climate change on injury exists. Here, the authors collect data during 2013-2019 in six provinces of China to estimate the associations between temperature and injury mortality, and to project future mortality burden attributable to temperature change driven by climate change.

Jianxiong Hu
Guanhao He
Wenjun Ma
ResearchOpen Access03 Jan 2023
Nature Communications

Volume: 14, P: 1-10
The tolerance balancing optimization with multiple constraints on the form and function of the discrete functional surface

Chuanyuan Zhou
Xiaomei Guo
Xiaoxiao Wei
ResearchOpen Access09 Jan 2025
Scientific Reports

Volume: 15, P: 1-14
Transcriptome and metabolome analysis reveals different photosynthetic characteristics of mulberry trees with different ploidy levels

Dan Liu
Qiang Lin
Changyu Qiu
ResearchOpen Access07 May 2025
Scientific Reports

Volume: 15, P: 1-15
The Somatic Mosaicism across Human Tissues Network

The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

Tim H. H. Coorens
Ji Won Oh
Yuqing Wang
Reviews02 Jul 2025
Nature

Volume: 643, P: 47-59
Giant anisotropic photonics in the 1D van der Waals semiconductor fibrous red phosphorus

One-dimensional van der Waals (1D vdW) materials derive interesting behaviour from dimensional confinement. Here the authors study a 1D vdW semiconductor, fibrous red phosphorous, and observe exceptional optical properties of large optical anisotropy and high photoluminescence.

Luojun Du
Yanchong Zhao
Zhipei Sun
ResearchOpen Access10 Aug 2021
Nature Communications

Volume: 12, P: 1-10
Crisaborole combined with vitamin D demonstrates superior therapeutic efficacy over either monotherapy in mice with allergic contact dermatitis

Huachun Wang
Hetong Li
Faming Tian
ResearchOpen Access29 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
Retraction Note: Blocking C-Raf alleviated high-dose small-volume radiation-induced epithelial mesenchymal transition in mice lung

Zhen-Yu Hong
Sanke Li
Ping Lu
Amendments and CorrectionsOpen Access07 Jul 2025
Scientific Reports

Volume: 15, P: 1
Unraveling HIV-1 transmission patterns through molecular surveillance in a hotspot in Yunnan Province, China

Hui Yang
Huichao Chen
Min Chen
ResearchOpen Access22 Mar 2025
Scientific Reports

Volume: 15, P: 1-11
Care Practices, Morbidity and Mortality of Preterm Neonates in China, 2013–2014: a Retrospective study

Fengdan Xu
Xiangyong Kong
Zhichun Feng
ResearchOpen Access27 Dec 2019
Scientific Reports

Volume: 9, P: 1-7
Gender Disparities in Lipid Goal Attainment among Type 2 Diabetes Outpatients with Coronary Heart Disease: Results from the CCMR-3B Study

Xiaomei Zhang
Linong Ji
Dayi Hu
ResearchOpen Access04 Oct 2017
Scientific Reports

Volume: 7, P: 1-7
A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12

Ding Ma, Xing Xie, Yongyong Shi and colleagues report a genome-wide association study of cervical cancer in the Han Chinese population. They identify two new susceptibility lociat 4q12 and 17q12.

Yongyong Shi
Li Li
Ding Ma
Research30 Jun 2013
Nature Genetics

Volume: 45, P: 918-922
A novel doxorubicin/CTLA-4 blocker co-loaded drug delivery system improves efficacy and safety in antitumor therapy

Wenli Yang
Qinghui Sun
Wu Wang
ResearchOpen Access01 Jun 2024
Cell Death & Disease

Volume: 15, P: 1-13
Biological and antibacterial properties of the micro-nanostructured hydroxyapatite/chitosan coating on titanium

Baoe Li
Xiaomei Xia
Hongshui Wang
ResearchOpen Access01 Oct 2019
Scientific Reports

Volume: 9, P: 1-10
The epidemiological and genetic characteristics of human parvovirus B19 in patients with febrile rash illnesses in China

Haoran Jiang
Qi Qiu
Xiaomei Li
ResearchOpen Access23 Sept 2023
Scientific Reports

Volume: 13, P: 1-9
Identification of a class of potent USP25/28 inhibitors with broad-spectrum anti-cancer activity

Jin Peng
Kun Jiang
Pumin Zhang
ResearchOpen Access08 Dec 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-3
Green transformation and performance synergy efficiency of china’s thermal power enterprises on the basis of the environmental tax burden

Xiao-yan Liu
Fang-rong Ren
Xiaomei Yuan
ResearchOpen Access21 Aug 2024
Scientific Reports

Volume: 14, P: 1-16
Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma

Yongping Cui
Hongyan Chen
Zhihua Liu
Research12 May 2020
Cell Research

Volume: 30, P: 902-913
Artificial intelligence to detect malignant eyelid tumors from photographic images

Zhongwen Li
Wei Qiang
Guohai Wu
ResearchOpen Access02 Mar 2022
npj Digital Medicine

Volume: 5, P: 1-9
Ensemble streamflow forecasting based on variational mode decomposition and long short term memory

Xiaomei Sun
Haiou Zhang
Juan Li
ResearchOpen Access11 Jan 2022
Scientific Reports

Volume: 12, P: 1-19
The impact of environmental regulation on green investment efficiency of thermal power enterprises in China-based on a three-stage exogenous variable model

Fang-rong Ren
Tao-feng Wu
Xiaomei Yuan
ResearchOpen Access10 Apr 2024
Scientific Reports

Volume: 14, P: 1-17
Predicting bleeding risk in a Chinese immune thrombocytopenia (ITP) population: development and assessment of a new predictive nomogram

Mingjing Wang
Weiyi Liu
Xiaomei Hu
ResearchOpen Access18 Sept 2020
Scientific Reports

Volume: 10, P: 1-10
Coupled changes in soil organic carbon fractions and microbial community composition in urban and suburban forests

Xueying Zhang
Xiaomei Chen
Hui Wei
ResearchOpen Access28 Sept 2020
Scientific Reports

Volume: 10, P: 1-12
Modelling and Analyzing Virus Mutation Dynamics of Chikungunya Outbreaks

Xiaomei Feng
Xi Huo
Jianhong Wu
ResearchOpen Access27 Feb 2019
Scientific Reports

Volume: 9, P: 1-15
RBC transfusion and necrotizing enterocolitis in very preterm infants: a multicenter observational study

Dan Dang
Xinyue Gu
Joseph Ting
ResearchOpen Access21 Jun 2024
Scientific Reports

Volume: 14, P: 1-8
PiT2 regulates neuronal outgrowth through interaction with microtubule-associated protein 1B

Xi-Xiang Ma
Xiangyang Li
Jing-Yu Liu
ResearchOpen Access19 Dec 2017
Scientific Reports

Volume: 7, P: 1-13
Multiple gene mutations identified in patients infected with influenza A (H7N9) virus

Cuicui Chen
Mingbang Wang
Wenhao Zhou
ResearchOpen Access09 May 2016
Scientific Reports

Volume: 6, P: 1-9
An efficient micropropagation protocol for an endangered ornamental tree species (Magnolia sirindhorniae Noot. & Chalermglin) and assessment of genetic uniformity through DNA markers

Yuanyuan Cui
Yanwen Deng
Ruchun Xi
ResearchOpen Access03 Jul 2019
Scientific Reports

Volume: 9, P: 1-10
Association between the risk of necrotizing enterocolitis and intrauterine growth: a multicenter cohort study

Dan Dang
Siyuan Jiang
Joseph Ting
Research13 Jun 2025
Pediatric Research

P: 1-7
Improvement of awareness, treatment and control of hypertension among chronic kidney disease patients in China from 1999 to 2005

Yu Wang
Luxia Zhang
Hai Yan Wang
Research04 Jun 2009
Hypertension Research

Volume: 32, P: 444-449
Econazole nitrate inhibits PI3K activity and promotes apoptosis in lung cancer cells

Chao Dong
Runxiang Yang
Marie Chia-mi Lin
ResearchOpen Access21 Dec 2017
Scientific Reports

Volume: 7, P: 1-11
RETRACTED ARTICLE: Blocking C-Raf alleviated high-dose small-volume radiation-induced epithelial mesenchymal transition in mice lung

Zhen-Yu Hong
Sanke Li
Ping Lu
ResearchOpen Access07 Jul 2020
Scientific Reports

Volume: 10, P: 1-10
Author Correction: Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma

Yongping Cui
Hongyan Chen
Zhihua Liu
Amendments and Corrections17 Feb 2022
Cell Research

Volume: 32, P: 415-416
Transcriptomic profiling of Poa pratensis L. under treatment of various phytohormones

Chen Meng
Xiaomei Peng
Xudong Sun
ResearchOpen Access15 Mar 2024
Scientific Data

Volume: 11, P: 1-11

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