Despite the promising potential of the perfluoro-tert-butyl (PFtB) group in diverse fields, incorporating PFtB into organic molecules remains challenging. Here, the authors describe a stable and scalable reagent for radical-type perfluoro-tert-butylation, which is synthesized in large scale from commercial perfluoro-tert-butanol and a designed benzothiazole hypervalent iodonium salt.
- Ruitong Zhang
- Shengqi Zhou
- Chao Chen
