Nature Search

Microbiota-shaped neutrophil senescence regulates sexual dimorphism in bladder cancer

Sexual dimorphism is a feature of many cancers, but how this functions is often unclear. Here the authors show that in bladder cancer it is regulated by a microbiota–lurasidone–LCN2 circuit that controls the accumulation of a subpopulation of senescence-like neutrophils.

Qingchen Zhu
Guiheng Zhang
Yichuan Xiao
Research11 Apr 2025
Nature Immunology

Volume: 26, P: 722-736
Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids

Coptis chinensis represents an early-diverging eudicot lineage with diverse medicinal applications. Here, the authors report its chromosome-scale genome assembly, infer a single ancient whole-genome duplication, and characterize the function of CYP719 in diversification of protoberberine-type alkaloids.

Yifei Liu
Bo Wang
Jing Nie
ResearchOpen Access02 Jun 2021
Nature Communications

Volume: 12, P: 1-13
Author Correction: Mapping global lake dynamics reveals the emerging roles of small lakes

Xuehui Pi
Qiuqi Luo
Brett A. Bryan
Amendments and CorrectionsOpen Access25 Oct 2022
Nature Communications

Volume: 13, P: 1
Screening and diagnosis of cardiovascular disease using artificial intelligence-enabled cardiac magnetic resonance imaging

A two-step, video-based deep learning model is developed to first screen for cardiac anomalies using noncontrast magnetic resonance imaging, followed by diagnosis of 11 types of cardiovascular disease using gadolinium enhancement-based imaging.

Yan-Ran (Joyce) Wang
Kai Yang
Shihua Zhao
ResearchOpen Access13 May 2024
Nature Medicine

Volume: 30, P: 1471-1480
De novo production of protoberberine and benzophenanthridine alkaloids through metabolic engineering of yeast

Protoberberine alkaloids and benzophenanthridine alkaloids (BZDAs) are plant derived natural products with many pharmaceutical properties. Here, the authors report de novo synthesizing of a series of these compounds by engineered Saccharomyces cerevisiae.

Xiang Jiao
Xiaozhi Fu
Yun Chen
ResearchOpen Access09 Oct 2024
Nature Communications

Volume: 15, P: 1-16
An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness

Activated Notch signalling promotes cancer metastasis and stemness. Here the authors show that Notch1 activates transcription of DNA replication factor RCF4 and that RCF4 binds and stabilises Notch1 intracellular domain (NICD1) to promote cancer metastasis.

Lei Liu
Tianyu Tao
Han Tian
ResearchOpen Access11 May 2021
Nature Communications

Volume: 12, P: 1-16
sFlt-1/PIGF ratio positive associated with non-dipper type change in ambulatory blood pressure monitoring(ABPM) for preeclampsia development

Yunshan Chen
Xiaodan Di
Huishu Liu
ResearchOpen Access28 Nov 2023
Hypertension Research

Volume: 47, P: 849-858
Species richness prediction and priority conservation planning for rare Michelia species in China

Jimin Tang
Zhi Chen
Xiuyu Li
ResearchOpen Access23 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Mapping global lake dynamics reveals the emerging roles of small lakes

Lakes are essential components of the hydrological and biogeochemical cycles. Here, Pi et al develop a global lake dataset called GLAKES via high-resolution satellite images and deep learning to examine global lake changes over four decades.

Xuehui Pi
Qiuqi Luo
Brett A. Bryan
ResearchOpen Access01 Oct 2022
Nature Communications

Volume: 13, P: 1-12
Investigation of prevention of mother to child HIV transmission program from 2011 to 2017 in Suzhou, China

Tian Gong
Huiying Wang
Jing Wang
ResearchOpen Access24 Dec 2018
Scientific Reports

Volume: 8, P: 1-7
Distorted octahedral sites drive early formation and stabilisation of nickel oxyhydroxides in trimetallic nickel–iron–molybdenum oxides

Trimetallic nickel–iron–molybdenum oxides are good electrocatalysts despite severe molybdenum dissolution. Here, it is found that molybdenum induces the formation of nickel vacancies and distorts octahedral nickel sites, which induces the formation and stabilization of active nickel oxyhydroxides.

Mouna Rafei
Alexis Piñeiro-García
Eduardo Gracia-Espino
ResearchOpen Access05 Jun 2025
Communications Materials

Volume: 6, P: 1-11
The activity and immune dynamics of PD-1 inhibition on high-risk pulmonary ground glass opacity lesions: insights from a single-arm, phase II trial

Bo Cheng
Caichen Li
Wenhua Liang
ResearchOpen Access19 Apr 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-13
HIF1A facilitates hypoxia-induced changes in H3K27ac modification to promote myometrial contractility

Multiomics identifies HIF1A as a key mediator of H3K27ac modifications that regulate gene expression and enhance myometrial cell contractions under hypoxia during labour, providing potential therapeutic targets for parturition-related disorders.

Kaiyuan Ji
Bolun Wen
Huishu Liu
ResearchOpen Access21 Mar 2025
Communications Biology

Volume: 8, P: 1-15
Metabolic profiling and transcriptome analysis of Sinomenium acutum provide insights into the biosynthesis of structurally diverse benzylisoquinoline alkaloids

Xiuyu Liu
Jicong Chen
Ying Ma
ResearchOpen Access18 Feb 2025
Scientific Reports

Volume: 15, P: 1-15
Precision encoder grating mounting: a near-sensor computing approach

Jingyi Yu
Runjiang Dou
Liyuan Liu
ResearchOpen Access27 Sept 2024
Scientific Reports

Volume: 14, P: 1-15
Achievement splitting for topological states with pseudospin in phase modulation by using gyromagnetic photonic crystals

Liu He
Yuting Yang
Jianquan Yao
ResearchOpen Access27 Jul 2024
Scientific Reports

Volume: 14, P: 1-9
Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethality

Pu Li
Tingting Chen
Xiuyu Cai
ResearchOpen Access13 Jul 2022
Cell Death & Disease

Volume: 13, P: 1-13
GTF2E2 is a novel biomarker for recurrence after surgery and promotes progression of esophageal squamous cell carcinoma via miR-139-5p/GTF2E2/FUS axis

Yujie Zhang
Yuxin Zhang
Li Zhang
ResearchOpen Access02 Dec 2021
Oncogene

Volume: 41, P: 782-796
Hybrid energy storage configuration method for wind power microgrid based on EMD decomposition and two-stage robust approach

Xiuyu Yang
Xiaoyu Ye
Qi Guo
ResearchOpen Access01 Feb 2024
Scientific Reports

Volume: 14, P: 1-19
Lentinan improves intestinal inflammation and gut dysbiosis in antibiotics-induced mice

Xiuyu Ji
Le Su
Lin Zhao
ResearchOpen Access15 Nov 2022
Scientific Reports

Volume: 12, P: 1-12
Porcine intraepithelial lymphocytes undergo migration and produce an antiviral response following intestinal virus infection

When piglets are infected with intestinal virus, porcine intraepithelial lymphocytes undergo intra-and trans-epithelial migration promoted by chemokines from infected epithelial cells and produce an antiviral response.

Yuchen Li
Yichao Ma
Qian Yang
ResearchOpen Access22 Mar 2022
Communications Biology

Volume: 5, P: 1-16
Magnetic Resonance Imaging with Superparamagnetic Iron Oxide Fails to Track the Long-term Fate of Mesenchymal Stem Cells Transplanted into Heart

Ning Ma
Huaibing Cheng
Shihua Zhao
ResearchOpen Access12 Mar 2015
Scientific Reports

Volume: 5, P: 1-9
More need to optimize the prediction model of sFlt- 1/PIGF ratio and ambulatory blood pressure monitoring in preeclampsia

Yunshan Chen
Xiuyu Pan
Huishu Liu
Correspondence21 Feb 2024
Hypertension Research

Volume: 47, P: 1438-1439

Search

Microbiota-shaped neutrophil senescence regulates sexual dimorphism in bladder cancer

Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids

Author Correction: Mapping global lake dynamics reveals the emerging roles of small lakes

Screening and diagnosis of cardiovascular disease using artificial intelligence-enabled cardiac magnetic resonance imaging

De novo production of protoberberine and benzophenanthridine alkaloids through metabolic engineering of yeast

An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness

sFlt-1/PIGF ratio positive associated with non-dipper type change in ambulatory blood pressure monitoring(ABPM) for preeclampsia development

Species richness prediction and priority conservation planning for rare Michelia species in China

Mapping global lake dynamics reveals the emerging roles of small lakes

Investigation of prevention of mother to child HIV transmission program from 2011 to 2017 in Suzhou, China

Distorted octahedral sites drive early formation and stabilisation of nickel oxyhydroxides in trimetallic nickel–iron–molybdenum oxides

The activity and immune dynamics of PD-1 inhibition on high-risk pulmonary ground glass opacity lesions: insights from a single-arm, phase II trial

HIF1A facilitates hypoxia-induced changes in H3K27ac modification to promote myometrial contractility

Metabolic profiling and transcriptome analysis of Sinomenium acutum provide insights into the biosynthesis of structurally diverse benzylisoquinoline alkaloids

Precision encoder grating mounting: a near-sensor computing approach

Achievement splitting for topological states with pseudospin in phase modulation by using gyromagnetic photonic crystals

Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethality

GTF2E2 is a novel biomarker for recurrence after surgery and promotes progression of esophageal squamous cell carcinoma via miR-139-5p/GTF2E2/FUS axis

Hybrid energy storage configuration method for wind power microgrid based on EMD decomposition and two-stage robust approach

Lentinan improves intestinal inflammation and gut dysbiosis in antibiotics-induced mice

Porcine intraepithelial lymphocytes undergo migration and produce an antiviral response following intestinal virus infection

Magnetic Resonance Imaging with Superparamagnetic Iron Oxide Fails to Track the Long-term Fate of Mesenchymal Stem Cells Transplanted into Heart

More need to optimize the prediction model of sFlt- 1/PIGF ratio and ambulatory blood pressure monitoring in preeclampsia

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