Nanozymes can be used for targeting reactive oxygen species (ROS) to alleviate myocardial ischemia/reperfusion (I/R) injury, but hindered by catalytic performance and toxicity concerns. Here the authors report multienzyme-mimicking and biocompatible Pt-NC single-atom nanozymes as an efficient ROS decomposer for restoring cellular homeostasis and mitigating apoptotic progression after I/R injury.
- Tianbao Ye
- Cheng Chen
- Chengxing Shen
