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Showing 1–4 of 4 results
Advanced filters: Author: Xu-Min Cai Clear advanced filters

  • To date we have a myriad of luminogenes at our deposal but many of them face problems like weakened emission in the aggregated state as well as poor sustainability. Here, the authors develop a class of rosin-derived luminogens with aggregation induced emission properties providing good biocompatibility and demonstrate their application in organelle imaging.

    • Xu-Min Cai
    • Yuting Lin
    • Ben Zhong Tang
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-9

  • Intracellular regulation of small molecule aggregation is challenging. Here, the authors achieved tumor-targeted aggregation of an aggregation-induced emission photosensitizer (AIE-PS), TBmA, using γ-glutamyl transferase, an enzyme overexpressed in tumors, and showed this causes ferroptosis in cancer cells through photodynamic therapy.

    • Wen-Jin Wang
    • Rongyuan Zhang
    • Ben Zhong Tang
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11

  • Obesity is a significant health risk, and current treatments are inadequate. This study reveals that AA005, an annonaceous acetogenin mimic, targets mitochondrial HADHA in adipose tissue to boost thermogenesis via the UCP1 pathway, providing a promising new strategy for obesity treatment.

    • Bing Han
    • Zhan-Ming Li
    • Li-Shun Wang
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • Biorenewable feedstocks are important for developing more sustainable materials, but developing processes can be challenging due to incompatible reaction conditions. Here, the authors report the one-pot preparation of aggregation-induced emission luminogens from lignin moieties.

    • Tenglong Guo
    • Yuting Lin
    • Tao Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11