Nature Search

Travel burden increases the risk of advanced stage at diagnosis of breast cancer in Kashgar, China

Shengyuan Liang
Zhiqiang Jia
Ailing Ma
ResearchOpen Access25 Jul 2025
Scientific Reports

Volume: 15, P: 1-9
The blood lipidome fatty acid profile predicts the disease risk and clinical phenotypes of Alzheimer’s disease: associations from two prospective cohort studies

Wen-Zheng Liu
Liang-Yu Huang
Wei Xu
ResearchOpen Access06 Oct 2025
Translational Psychiatry

Volume: 15, P: 1-11
Study of Ink stick unearthed from the tomb of Fan Xiaochong in Shaanxi Province

Daishi Qi
Feng Sun
Xuwei Chen
ResearchOpen Access13 Aug 2025
npj Heritage Science

Volume: 13, P: 1-10
AKT-induced lncRNA VAL promotes EMT-independent metastasis through diminishing Trim16-dependent Vimentin degradation

The role of long non-coding RNA (lncRNA) in AKT-driven tumor development is unclear. Here, the authors identify VAL (Vimentin associated lncRNA) to be directly induced by AKT/STAT3 signaling and report a lncRNA-mediated mechanism for active AKT-driven EMT-independent lung adenocarcinoma metastasis.

Han Tian
Rong Lian
Junchao Cai
ResearchOpen Access12 Oct 2020
Nature Communications

Volume: 11, P: 1-15
An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness

Activated Notch signalling promotes cancer metastasis and stemness. Here the authors show that Notch1 activates transcription of DNA replication factor RCF4 and that RCF4 binds and stabilises Notch1 intracellular domain (NICD1) to promote cancer metastasis.

Lei Liu
Tianyu Tao
Han Tian
ResearchOpen Access11 May 2021
Nature Communications

Volume: 12, P: 1-16
Relationships of PGRN with sTREM2 in AD continuum and non-AD pathophysiology and their reciprocal roles in modulating amyloid pathology: two population-based study

Liang-Yu Huang
Chen-Chen Tan
Dariella Fernandez
ResearchOpen Access08 Jul 2025
Translational Psychiatry

Volume: 15, P: 1-11
Global expansion of tropical cyclone precipitation footprint

The tropical cyclone (TC) precipitation footprint has expanded globally. Interpretable machine learning reveals that this footprint is majorly controlled by TC wind speed, location, sea surface temperature, wind shear, and total water column vapor.

Lianjie Qin
Laiyin Zhu
Jianguo Chen
ResearchOpen Access06 Jun 2024
Nature Communications

Volume: 15, P: 1-10
Nanosecond optical switching and control system for data center networks

Several challenges still impede the deployment of optical switches in data centers. The authors report an optical switching and control system to synergistically overcome these challenges and provide enhanced performance for data center applications.

Xuwei Xue
Nicola Calabretta
ResearchOpen Access26 Apr 2022
Nature Communications

Volume: 13, P: 1-8
Phenylalanine impairs insulin signaling and inhibits glucose uptake through modification of IRβ

Whether amino acids act on cellular insulin signaling remains unclear. Here, the authors find that phenylalanine modifies insulin receptor beta (IRβ) and inactivates insulin signaling and glucose uptake and positively correlated with T2D onset.

Qian Zhou
Wan-Wan Sun
Shi-Min Zhao
ResearchOpen Access25 Jul 2022
Nature Communications

Volume: 13, P: 1-19
Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients

Overnutrition has been linked to increased risk of cancer. Here, the authors show that exceeding nutrients suppress Enoyl-CoA hydratase-1 (ECHS1) activity by inducing its acetylation resulting in accumulation of fatty acids and branched-chain amino acids and oncogenic mTOR activation.

Ya-Kun Zhang
Yuan-Yuan Qu
Wei Xu
ResearchOpen Access06 Sept 2017
Nature Communications

Volume: 8, P: 1-16
UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer

Kanghua Xiao
Shengmeng Peng
Tianxin Lin
ResearchOpen Access08 Jul 2023
Cell Death & Disease

Volume: 14, P: 1-13
AARS2-catalyzed lactylation induces follicle development and premature ovarian insufficiency

Zhi-Ling Zhang
Shu-Ting Ren
Wei Xu
ResearchOpen Access29 Apr 2025
Cell Death Discovery

Volume: 11, P: 1-16
Clinical information from repeated blood pressure measurements in the management of heart failure with preserved ejection fraction

Fang-Fei Wei
Yuanyuan Zhou
Chen Liu
Research15 Nov 2022
Hypertension Research

Volume: 46, P: 475-484
Environmental determinants and demographic influences on global urban microbiomes, antimicrobial resistance and pathogenicity

Yang Chen
Xi Fu
Yu Sun
ResearchOpen Access07 Dec 2023
npj Biofilms and Microbiomes

Volume: 9, P: 1-12
A case study on the bearing characteristics of a bottom uplift pile in a layered foundation

Laping He
Xuwei Chen
Zhao Long
ResearchOpen Access28 Dec 2022
Scientific Reports

Volume: 12, P: 1-14
Characteristics of precipitation changes during tropical cyclone processes in China from 1980 to 2019

Guangran Zhai
Wei Xu
Xinli Liao
ResearchOpen Access13 Jun 2024
Scientific Reports

Volume: 14, P: 1-12
Recent northward shift of tropical cyclone economic risk in China

Lianjie Qin
Laiyin Zhu
Jianguo Chen
ResearchOpen Access31 May 2024
npj Natural Hazards

Volume: 1, P: 1-9
Author Correction: Recent northward shift of tropical cyclone economic risk in China

Lianjie Qin
Laiyin Zhu
Jianguo Chen
Amendments and CorrectionsOpen Access24 Jun 2024
npj Natural Hazards

Volume: 1, P: 1

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