Cerebellar ataxia, a hallmark of cerebellar degeneration (CBND), is driven by mitochondrial dysfunction in Purkinje cells. In this study, transplanting mitochondria into CBND mice improve mitochondrial function, reduce mitophagy, and reduce ataxia.
- Shu-Jiao Li
- Qian-Wen Zheng
- Ya-Yun Wang