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Showing 1–4 of 4 results
Advanced filters: Author: Yalin Cong Clear advanced filters

  • While vaccines have curbed the COVID-19 pandemic, effective therapeutic treatments are few, and might be challenged by SARS-CoV-2 variants. A biocompatible, antiviral two-dimensional nanomaterial is now reported that firmly adsorbs the virus by interaction with the spike protein, inducing the conformational changes that lead to inhibition of viral infection in vitro and in animal models.

    • Guofang Zhang
    • Yalin Cong
    • Yang Li
    Research
    Nature Nanotechnology
    Volume: 17, P: 993-1003

  • There is a need to understand how nanomaterials interact with biological systems. Here, the authors report the surface chemistry of graphene oxide nanosheets (GOs) influences the structure of low-density lipoprotein and changes lipid metabolism pathways including LDL recognition, uptake, hydrolysis, efflux, and lipid droplet formation.

    • Junguang Wu
    • Xuan Bai
    • Liming Wang
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • Characterizing the soft protein corona on nanoparticles i.e. the outer layer of the corona, remains a longstanding challenge. Here, the authors develop an in situ method to monitor the dynamic processes of multilayered corona formation and evolution that offers a universal strategy to characterize the soft corona proteome.

    • Didar Baimanov
    • Jing Wang
    • Chunying Chen
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14

  • Understanding the in vivo biotransformation of nanomaterials used for biomedical applications might shed light on their long-term effects and safety. Here the authors show that molybdenum derived from nanomaterials is mainly transported in the liver, in a corona-mediated process, and is incorporated in molybdoenzymes, with an effect on liver metabolism.

    • Mingjing Cao
    • Rong Cai
    • Chunying Chen
    Research
    Nature Nanotechnology
    Volume: 16, P: 708-716