Fusobacterium nucleatum is a commensal microorganism and opportunistic pathogen, with a pathogenic role in periodontal disease, inflammatory bowel disease and various cancers, most notably colorectal cancer. This Review discusses F. nucleatum and its ecological niches and virulence factors, links with disease, oncogenic mechanisms, and emerging diagnostic approaches and therapeutic strategies.
- Shan-Shan Jiang
- Ying-Xuan Chen
- Jing-Yuan Fang
