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Scientific Reports (20)
Oncogene (6)
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Showing 1–50 of 63 results

Advanced filters: Author: Yinyin Li Clear advanced filters

Natural allelic variation confers high resistance to sweet potato weevils in sweet potato

Sweet potato weevils (SPWs) pose one of the most significant challenges to sweet potato production. This study identifies two major SPW-resistant genes, SPWR1/2, and provides new insights into the mechanism of sweet potato defence against SPWs.

Xu Liu
Yaru Wang
Xingliang Hou
Research14 Nov 2022
Nature Plants

Volume: 8, P: 1233-1244
A large-scale, multi-centre validation study of an AI-empowered blood-based test for multi-cancer early detection

Yong Shen
Yong Xia
Mao Mao
ResearchOpen Access08 Oct 2025
npj Precision Oncology

Volume: 9, P: 1-9
Noble metal-comparable SERS enhancement from semiconducting metal oxides by making oxygen vacancies

Surface-enhanced Raman spectroscopy is widely used for rapid and sensitive molecular detection in chemistry and biology, but typically relies on noble metals. Here the authors report a non-stoichiometric semiconducting material with defect-rich surface that displays excellent detection limits and enhancement factors.

Shan Cong
Yinyin Yuan
Zhigang Zhao
ResearchOpen Access17 Jul 2015
Nature Communications

Volume: 6, P: 1-7
Saddle curvature association of nsP1 facilitates the replication complex assembly of Chikungunya virus in cells

Viruses exploit host cell machinery for replication, but their spatial cues remain elusive. Using nanochip-enabled membrane shaping, the authors discover saddle curvature association of viral proteins, revealing a new spatial regulation mechanism.

Xinwen Miao
Michelle Cheok Yien Law
Wenting Zhao
ResearchOpen Access08 May 2025
Nature Communications

Volume: 16, P: 1-18
Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma

Swanton and colleagues present a clonal expression signature, ORACLE, which, in combination with clinicopathological and molecular risk factors, can predict survival of patients with lung adenocarcinoma, and they prospectively validate its prognostic value.

Dhruva Biswas
Yun-Hsin Liu
Charles Swanton
ResearchOpen Access09 Jan 2025
Nature Cancer

Volume: 6, P: 86-101
Activation of protein kinase C δ by the c-Abl tyrosine kinase in response to ionizing radiation

Zhi-Min Yuan
Taiju Utsugisawa
Donald Kufe
Research23 Apr 1998
Oncogene

Volume: 16, P: 1643-1648
Correction: Clinical investigation on nebulized human umbilical cord MSC-derived extracellular vesicles for pulmonary fibrosis treatment

Meng Li
Huaping Huang
Zhijie Chang
Amendments and CorrectionsOpen Access17 Jul 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1
Pro-apoptotic effect of the c-Abl tyrosine kinase in the cellular response to 1-β-D-arabinofuranosylcytosine

Yinyin Huang
Zhi-Min Yuan
Donald W Kufe
Research16 Oct 1997
Oncogene

Volume: 15, P: 1947-1952
The conceptual structure of human relationships across modern and historical cultures

Cheng et al. explore the universality and cultural variability in how people understand human relationships, revealing a five-dimensional framework for relationship concepts across both modern and ancient societies.

Xi Cheng
Haroon Popal
Yin Wang
Research13 Mar 2025
Nature Human Behaviour

Volume: 9, P: 1162-1175
Architecture of the baculovirus nucleocapsid revealed by cryo-EM

Baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is used as a bioinsecticide and a protein expression vector. Here, the authors report structures of cylindrical body of the AcMNPV nucleocapsid, as well as of both the nucleocapsid head and base.

Xudong Jia
Yuanzhu Gao
Qinfen Zhang
ResearchOpen Access18 Nov 2023
Nature Communications

Volume: 14, P: 1-15
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

Integrative analysis of copy number and gene expression in 2,000 primary breast tumours with long-term clinical follow-up revealed putative cis-acting driver genes, novel subgroups and trans-acting aberration hotspots that modulate subgroup-specific gene networks.

Christina Curtis
Sohrab P. Shah
Samuel Aparicio
Research18 Apr 2012
Nature

Volume: 486, P: 346-352
The clinical characteristics of anemia in native adults living at different altitudes of the Tibetan Plateau

Jie Fang
Ran Li
Kai Xue
ResearchOpen Access24 Feb 2023
Scientific Reports

Volume: 13, P: 1-6
Sgrgan: sketch-guided restoration for traditional Chinese landscape paintings

Qiyao Hu
Weilu Huang
Jianping Fan
ResearchOpen Access24 May 2024
Heritage Science

Volume: 12, P: 1-28
A robust pipeline for rapid production of versatile nanobody repertoires

This paper presents an efficient method for generating nanobodies with high affinity and high specificity. In addition, a collection of nanobodies specific for GFP or mCherry that resulted from this work is described.

Peter C Fridy
Yinyin Li
Michael P Rout
Research02 Nov 2014
Nature Methods

Volume: 11, P: 1253-1260
NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4

Cytoplasmic nucleic acids induce interferon responses via a pathway dependent on the kinase TBK1 and transcription factor IRF3. Wang and colleagues show that the receptor NLRP4 limits this response by recruiting the ubiquitin ligase DTX4 to target TBK1 for proteasomal degradation.

Jun Cui
Yinyin Li
Rong-Fu Wang
Research04 Mar 2012
Nature Immunology

Volume: 13, P: 387-395
Intramyocardial hemorrhage drives fatty degeneration of infarcted myocardium

It is unclear why hemorrhagic myocardial infarctions (hMI) are destined for adverse outcomes. Here, the authors show that hMI drives fatty degeneration of infarct territories and contributes to adverse remodeling of the heart, which can be mitigated via timely depletion of iron within the hMI zone.

Ivan Cokic
Shing Fai Chan
Rohan Dharmakumar
ResearchOpen Access27 Oct 2022
Nature Communications

Volume: 13, P: 1-18
The role of mechano-regulated YAP/TAZ in erectile dysfunction

Phosphodiesterase type 5 inhibitors (PDE5is) are used to treat erectile dysfunction, however, not all patients respond to PDE5i treatment. Here the authors report that YAP/TAZ activity contributes to erectile dysfunction and targeting YAP/TAZ improves erectile function in a PDE5i non-respondent rat model.

Mintao Ji
Dongsheng Chen
Lei Chang
ResearchOpen Access23 Jun 2023
Nature Communications

Volume: 14, P: 1-16
Characteristics of emergency patients with markedly elevated D-dimer levels

Ning Tang
Yinyin Pan
Dengju Li
ResearchOpen Access08 May 2020
Scientific Reports

Volume: 10, P: 1-5
Facile construction of ZIF-94/PAN nanofiber by electrospinning for the removal of Co(II) from wastewater

Cong Yin
Yinyin Peng
Guoyuan Yuan
ResearchOpen Access03 Jan 2024
Scientific Reports

Volume: 14, P: 1-11
Clinical investigation on nebulized human umbilical cord MSC-derived extracellular vesicles for pulmonary fibrosis treatment

Meng Li
Huaping Huang
Zhijie Chang
ResearchOpen Access04 Jun 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-18
A hybrid human fall detection method based on modified YOLOv8s and AlphaPose

Lei Liu
Yeguo Sun
Yihong Liu
ResearchOpen Access21 Jan 2025
Scientific Reports

Volume: 15, P: 1-17
Induction chemotherapy followed by camrelizumab plus apatinib and chemotherapy as first-line treatment for extensive-stage small-cell lung cancer: a multicenter, single-arm trial

Ming Liu
Guihuan Qiu
Chengzhi Zhou
ResearchOpen Access18 Feb 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-10
Hypoxia-induced CREB cooperates MMSET to modify chromatin and promote DKK1 expression in multiple myeloma

Yinyin Xu
Jing Guo
Zhiqiang Liu
ResearchOpen Access08 Jan 2021
Oncogene

Volume: 40, P: 1231-1241
Metabolic control of the scaffold protein TKS5 in tissue-invasive, proinflammatory T cells

Previous studies have defined a state of metabolic reprogramming in rheumatoid arthritis (RA) T cells. Here Weyand and colleagues show that the rewiring of cellular metabolism renders RA T cells tissue invasive, directly promoting disease-inducing effector functions.

Yi Shen
Zhenke Wen
Cornelia M Weyand
Research24 Jul 2017
Nature Immunology

Volume: 18, P: 1025-1034
Effect of therapeutic erythrocytapheresis on outcomes and renal benefit in patients with high-altitude polycythemia: a real-world study

Yan Ouyang
Yinyin Zhang
Kai Qing
ResearchOpen Access23 Nov 2024
Scientific Reports

Volume: 14, P: 1-10
Prediction of aboveground grassland biomass on the Loess Plateau, China, using a random forest algorithm

Yinyin Wang
Gaolin Wu
Zhouping Shangguan
ResearchOpen Access31 Jul 2017
Scientific Reports

Volume: 7, P: 1-10
Nuclear ARP2/3 drives DNA break clustering for homology-directed repair

Polymerization of actin in the cell nucleus, promoted by the ARP2/3 complex, drives the clustering of double-strand DNA breaks into nuclear compartments where they can undergo homology-directed repair.

Benjamin R. Schrank
Tomas Aparicio
Jean Gautier
Research20 Jun 2018
Nature

Volume: 559, P: 61-66
N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation

Pathogenic human CD4⁺ T cells in rheumatoid arthritis have hyperactivated metabolism. Weyand and colleagues show that this phenotype is associated with less myristoylation of the energy sensor AMPK and dysregulated metabolic sensor mTORC1.

Zhenke Wen
Ke Jin
Cornelia M. Weyand
Research04 Feb 2019
Nature Immunology

Volume: 20, P: 313-325
Probiotic treatment induces changes in intestinal microbiota but does not alter SCFA levels in peritoneal dialysis patients—a randomized, placebo-controlled trial

Shengnan Zhou
Yinyin Yan
Na Tian
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-12
Evaluating different extraction solvents for GC-MS based metabolomic analysis of the fecal metabolome of adult and baby giant pandas

Yang Yang
Yanqiang Yin
Ting-Li Han
ResearchOpen Access19 Aug 2019
Scientific Reports

Volume: 9, P: 1-9
A human programmed death-ligand 1-expressing mouse tumor model for evaluating the therapeutic efficacy of anti-human PD-L1 antibodies

Anfei Huang
Di Peng
F. Xiao-Feng Qin
ResearchOpen Access16 Feb 2017
Scientific Reports

Volume: 7, P: 1-9
In-Situ Formation of Cobalt-Phosphate Oxygen-Evolving Complex-Anchored Reduced Graphene Oxide Nanosheets for Oxygen Reduction Reaction

Zhi-Gang Zhao
Jing Zhang
Qing-Wen Li
ResearchOpen Access23 Jul 2013
Scientific Reports

Volume: 3, P: 1-6
Lung adenocarcinoma promotion by air pollutants

Combination of epidemiology, preclinical models and ultradeep DNA profiling of clinical cohorts unpicks the inflammatory mechanism by which air pollution promotes lung cancer

William Hill
Emilia L. Lim
Charles Swanton
Research05 Apr 2023
Nature

Volume: 616, P: 159-167
A multicenter, randomized, double-blind, placebo-controlled phase 3 study of Socazolimab or placebo combined with carboplatin and etoposide in the first-line treatment of extensive-stage small cell lung cancer

Zhiwei Chen
Jianhua Chen
Xiaohui Yu
ResearchOpen Access13 Jan 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-8
Identification of an intraocular microbiota

Yuhua Deng
Xiaofei Ge
Lai Wei
ResearchOpen Access09 Mar 2021
Cell Discovery

Volume: 7, P: 1-12
Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma

In the TRACERx cohort of 171 patients with lung cancer, the ultrasensitive detection of ctDNA improves preoperative patient stratification, also in early-stage disease.

James R. M. Black
Gabor Bartha
Charles Swanton
ResearchOpen Access13 Jan 2025
Nature Medicine

Volume: 31, P: 70-76
Phosphorylation of FOXK2 at Thr13 and Ser30 by PDK2 sustains glycolysis through a positive feedback manner in ovarian cancer

Cancan Zhang
Yinyin Xu
Rong Zhang
ResearchOpen Access11 May 2024
Oncogene

Volume: 43, P: 1985-1999
Systematic evaluation of quantotypic peptides for targeted analysis of the human kinome

A method for generating a resource of quantotypic peptides for targeted proteomic analysis of human kinases is presented

Jonathan D Worboys
John Sinclair
Claus Jørgensen
Research24 Aug 2014
Nature Methods

Volume: 11, P: 1041-1044
A novel ZIC3 gene mutation identified in patients with heterotaxy and congenital heart disease

Shuolin Li
Sida Liu
Guoying Huang
ResearchOpen Access17 Aug 2018
Scientific Reports

Volume: 8, P: 1-12
Tissue factor promotes TREX1 protein stability to evade cGAS-STING innate immune response in pancreatic ductal adenocarcinoma

Yinyin Xue
Yue Wang
Ker Yu
ResearchOpen Access10 Dec 2024
Oncogene

Volume: 44, P: 739-752
Analysis of sequential hair segments reflects changes in the metabolome across the trimesters of pregnancy

Thibaut D. J. Delplancke
Jamie V. de Seymour
Philip N. Baker
ResearchOpen Access08 Jan 2018
Scientific Reports

Volume: 8, P: 1-12
A strategy for dissecting the architectures of native macromolecular assemblies

The molecular architecture of protein complexes can be determined using an optimal approach for isolating GFP-tagged complexes at native levels, combined with cross-linking, mass spectrometry analysis, and structure modeling from mass spectrometry-derived distance restraints.

Yi Shi
Riccardo Pellarin
Brian T Chait
Research05 Oct 2015
Nature Methods

Volume: 12, P: 1135-1138
Five serum fatty acids are associated with subclinical hypothyroidism in a Chinese pregnant population

Ting Zhang
Yinyin Xia
Philip N. Baker
ResearchOpen Access21 Apr 2020
Scientific Reports

Volume: 10, P: 1-9
Author Correction: Identification of an intraocular microbiota

Yuhua Deng
Xiaofei Ge
Lai Wei
Amendments and CorrectionsOpen Access15 May 2024
Cell Discovery

Volume: 10, P: 1
CREPT/RPRD1B promotes tumorigenesis through STAT3-driven gene transcription in a p300-dependent manner

Wanli Zhai
Xiongjun Ye
Zhijie Chang
ResearchOpen Access03 Feb 2021
British Journal of Cancer

Volume: 124, P: 1437-1448
Relationship between gut microbiota and nutritional status in patients on peritoneal dialysis

Na Tian
Yinyin Yan
Philip Kam-Tao Li
ResearchOpen Access28 Jan 2023
Scientific Reports

Volume: 13, P: 1-11
Impact of different growth hormone levels on gut microbiota and metabolism in short stature

Lan Li
Yu Wang
Zhihan Yan
Research06 Apr 2024
Pediatric Research

Volume: 96, P: 115-123
IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signaling

Zhili Rong
Anan Wang
Zhijie Chang
Research16 Dec 2008
Cell Research

Volume: 19, P: 208-215
Chemical compound cinobufotalin potently induces FOXO1-stimulated cisplatin sensitivity by antagonizing its binding partner MYH9

YongHao Li
Xiong Liu
Weiyi Fang
ResearchOpen Access18 Nov 2019
Signal Transduction and Targeted Therapy

Volume: 4, P: 1-12
DrugRepo: a novel approach to repurposing drugs based on chemical and genomic features

Yinyin Wang
Jehad Aldahdooh
Ziaurrehman Tanoli
ResearchOpen Access07 Dec 2022
Scientific Reports

Volume: 12, P: 1-13

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