Biobased furans are important chemical building blocks for the development of materials, but selective, efficient, and cost-effective scalable conversion of biobased furans remains elusive. Here, the authors report a transaminase from Shimia marina (SMTA) that enables the scalable amination of biobased furanaldehydes with high activity and broad substrate specificity and provide structural and mechanistic insights into SMTA activity.
- Pritam Giri
- Seonga Lim
- Hyungdon Yun