Bronchial epithelium is now believed to participate in the pathophysiology of bronchial asthma. In this report, the authors show that the ΔNp63 transcription factor, expressed in the basal layer of bronchus, modulates distinctive survival and immune-related bronchial epithelial responses. These results suggest functional significance of the epithelial shedding found in the pathology of bronchial asthma.
- Terufumi Kubo
- Mitsuhiro Tsujiwaki
- Toshihiko Torigoe
