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Advanced filters: Author: Yoshikuni Onodera Clear advanced filters

Structural basis for the inhibition of bacterial multidrug exporters

The first inhibitor-bound X-ray crystal structures of the bacterial multidrug efflux transporter AcrB and its homologue MexB are presented, with the inhibitor shown to bind the transporter through a narrow hydrophobic pit, thereby preventing rotation of AcrB and MexB monomers.

Ryosuke Nakashima
Keisuke Sakurai
Akihito Yamaguchi
Research30 Jun 2013
Nature

Volume: 500, P: 102-106
An mRNA vaccine candidate encoding H5HA clade 2.3.4.4b protects mice from clade 2.3.2.1a virus infection

Shiho Chiba
Maki Kiso
Yoshihiro Kawaoka
ResearchOpen Access14 Oct 2024
npj Vaccines

Volume: 9, P: 1-5
TBA₂₂₅, a fusion toxoid vaccine for protection and broad neutralization of staphylococcal superantigens

Arundhathi Venkatasubramaniam
Rajan P. Adhikari
M. Javad Aman
ResearchOpen Access01 Mar 2019
Scientific Reports

Volume: 9, P: 1-13