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Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variant

XBB.1.5 of SARS-CoV-2 is a descendant of XBB.1 and has mutations in spike and ORF8, making it more infectious to humans. Here, the authors examined in detail the differences in virological properties of the two variants.

Tomokazu Tamura
Takashi Irie
Takasuke Fukuhara
ResearchOpen Access08 Feb 2024
Nature Communications

Volume: 15, P: 1-17
Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants

XBB is the first recombinant, globally dominant variant of SARS-CoV-2. Here, the authors examine the variant’s origins and virological properties, showing it is the first example of SARS-CoV-2 improving its fitness through recombination.

Tomokazu Tamura
Jumpei Ito
Kei Sato
ResearchOpen Access16 May 2023
Nature Communications

Volume: 14, P: 1-20
PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover

Retinitis pigmentosa is a genetic disease causing degeneration of retinal pigment epithelial and photoreceptor cells. Here, the authors show that PNPLA6 regulates choline metabolism for retinal homeostasis, and its dysfunction leads to degeneration, which can be rescued by choline supplementation.

Takashi Ono
Yoshitaka Taketomi
Makoto Murakami
ResearchOpen Access13 Mar 2025
Nature Communications

Volume: 16, P: 1-23
A protein language model for exploring viral fitness landscapes

Ito et al. present CoVFit, an AI model that predicts variant fitness (transmissibility) from spike protein sequences alone. They further demonstrate its utility in forecasting viral evolution via single amino acid mutations.

Jumpei Ito
Adam Strange
Kei Sato
ResearchOpen Access13 May 2025
Nature Communications

Volume: 16, P: 1-16
Stereospecific Polymerization of Vinyl Acetate in Fluoroalcohols and Synthesis of Syndiotactic Poly(vinyl alcohol)

Yoshitaka Nagara
Kazunobu Yamada
Yoshio Okamoto
Research01 Jul 2001
Polymer Journal

Volume: 33, P: 534-539
Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Youngjune Bhak
Vasilis Raptis
Albert Tenesa
ResearchOpen Access28 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant

Recent Omicron SARS-CoV-2 subvariants independently acquire 5 key Spike mutations. Here, the authors evaluate the evolutionary importance of the 5 mutations and characterize the virological properties of variant BQ.1.1 harboring all 5 mutations.

Jumpei Ito
Rigel Suzuki
Kei Sato
ResearchOpen Access11 May 2023
Nature Communications

Volume: 14, P: 1-20
Effects of 2% sodium fluoride solution on the prevention of streptococcal adhesion to titanium and zirconia surfaces

Yukari Oda
Tadashi Miura
Yasutomo Yajima
ResearchOpen Access24 Feb 2021
Scientific Reports

Volume: 11, P: 1-9
Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1

JN.1 lineage is a globally dominant variant of SARS-CoV-2. Here, the authors examine structural insights into the BA.2.86 and JN.1 spike dynamics to help understand the mechanisms underlying SARS-CoV-2 infection and its neutralizing-antibody evasion.

Hisano Yajima
Yuki Anraku
Takao Hashiguchi
ResearchOpen Access07 Oct 2024
Nature Communications

Volume: 15, P: 1-14
Comparative pathogenicity of SARS-CoV-2 Omicron subvariants including BA.1, BA.2, and BA.5

The virological and pathological features of Omicron subvariants are compared in in vitro cellular and airway-on-a-chip and in vivo hamster models.

Tomokazu Tamura
Daichi Yamasoba
Takasuke Fukuhara
ResearchOpen Access24 Jul 2023
Communications Biology

Volume: 6, P: 1-12
Artificial intelligence can extract important features for diagnosing axillary lymph node metastasis in early breast cancer using contrast-enhanced ultrasonography

Tomohiro Oshino
Ken Enda
Masato Takahashi
ResearchOpen Access15 Feb 2025
Scientific Reports

Volume: 15, P: 1-11
One-third magnetization plateau in Quantum Kagome antiferromagnet

A range of non-trivial quantum phenomena can emerge from frustrated magnetic systems and a prime example is a quantum spin liquid. Here, the authors conduct specific heat and magnetization measurements on the Kapellasite-type compound InCu₃(OH)₆Cl₃ in order to characterize and define the range of the magnetization plateau in this material.

Moyu Kato
Yasuo Narumi
Hiroyuki K. Yoshida
ResearchOpen Access28 Dec 2024
Communications Physics

Volume: 7, P: 1-8
miR-23a promotes invasion of glioblastoma via HOXD10-regulated glial-mesenchymal transition

Kazuhiro Yachi
Masumi Tsuda
Shinya Tanaka
ResearchOpen Access28 Dec 2018
Signal Transduction and Targeted Therapy

Volume: 3, P: 1-10
A prospective compound screening contest identified broader inhibitors for Sirtuin 1

Shuntaro Chiba
Masahito Ohue
Masakazu Sekijima
ResearchOpen Access20 Dec 2019
Scientific Reports

Volume: 9, P: 1-12
Production of marmoset eggs and embryos from xenotransplanted ovary tissues

Runa Hirayama
Hiroaki Taketsuru
Kenji Sakimura
ResearchOpen Access24 Oct 2023
Scientific Reports

Volume: 13, P: 1-12
First On-Site True Gamma-Ray Imaging-Spectroscopy of Contamination near Fukushima Plant

Dai Tomono
Tetsuya Mizumoto
Toru Tanimori
ResearchOpen Access03 Feb 2017
Scientific Reports

Volume: 7, P: 1-10
Real-time single-cell imaging of protein secretion

Yoshitaka Shirasaki
Mai Yamagishi
Osamu Ohara
ResearchOpen Access22 Apr 2014
Scientific Reports

Volume: 4, P: 1-8

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Virological characteristics of the SARS-CoV-2 Omicron XBB.1.5 variant

Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants

PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover

A protein language model for exploring viral fitness landscapes

Stereospecific Polymerization of Vinyl Acetate in Fluoroalcohols and Synthesis of Syndiotactic Poly(vinyl alcohol)

Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant

Effects of 2% sodium fluoride solution on the prevention of streptococcal adhesion to titanium and zirconia surfaces

Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1

Comparative pathogenicity of SARS-CoV-2 Omicron subvariants including BA.1, BA.2, and BA.5

Artificial intelligence can extract important features for diagnosing axillary lymph node metastasis in early breast cancer using contrast-enhanced ultrasonography

One-third magnetization plateau in Quantum Kagome antiferromagnet

miR-23a promotes invasion of glioblastoma via HOXD10-regulated glial-mesenchymal transition

A prospective compound screening contest identified broader inhibitors for Sirtuin 1

Production of marmoset eggs and embryos from xenotransplanted ovary tissues

First On-Site True Gamma-Ray Imaging-Spectroscopy of Contamination near Fukushima Plant

Real-time single-cell imaging of protein secretion

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