Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Advertisement

Nature

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Scientific Reports (25)
Nature Communications (5)
Nature (4)
Journal of Human Genetics (3)
Nature Genetics (3)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (53)
Amendments and Corrections (2)
Reviews (2)

Subject Check one or more subjects to show results from those subjects only.

Biochemistry
Biotechnology
Cancer
Cell biology
Chemistry
Climate sciences
Computational biology and bioinformatics
Diseases
Drug discovery
Gastroenterology
Genetics
Health care
Immunology
Medical research
Microbiology
Neuroscience
Oncology
Physiology
Risk factors
Urology

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–50 of 57 results

Advanced filters: Author: Yoshiyuki Fukushima Clear advanced filters

Host control of persistent Epstein–Barr virus infection

Axel Schmidt
T. Madhusankha Alawathurage
Kerstin U. Ludwig
Research19 Feb 2026
Nature

P: 1-5
Randomized open-label non-inferiority trial of paracetamol or celecoxib for patients with chronic low back pain

Kazuhiro Hayashi
Kenji Miki
Masao Yukioka
ResearchOpen Access09 Dec 2025
Scientific Reports

Volume: 16, P: 1-8
Preexisting senescent fibroblasts in the aged bladder create a tumor-permissive niche through CXCL12 secretion

Meguro et al. show an accumulation of p16^high senescent fibroblasts in the aging bladder that serves as a cancer-permissive niche and promotes tumor growth by secreting CXCL12. Inhibition of senescence or CXCL12 signaling suppresses bladder tumor growth.

Satoru Meguro
Yoshikazu Johmura
Makoto Nakanishi
ResearchOpen Access09 Sept 2024
Nature Aging

Volume: 4, P: 1582-1597
DOCK2 is involved in the host genetics and biology of severe COVID-19

A genome-wide association study highlights a variant in DOCK2, which is common in East Asian populations but rare in Europeans, as a host genetic risk factor for severe COVID-19.

Ho Namkoong
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access08 Aug 2022
Nature

Volume: 609, P: 754-760
MET signaling drives acquired resistance to erdafitinib in muscle-invasive bladder cancer cells

Syunta Makabe
Kyoka Hoshi
Michiru Nishita
ResearchOpen Access28 Nov 2025
Cell Death & Disease

Volume: 16, P: 1-14
The prevalence and predictive factors of nocturnal polyuria in Japanese patients with nocturia: a multicentral retrospective cohort study

Koji Iinuma
Yoshinori Nishino
Takuya Koie
ResearchOpen Access24 Oct 2023
Scientific Reports

Volume: 13, P: 1-8
Blood DNA virome associates with autoimmune diseases and COVID-19

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Noah Sasa
Shohei Kojima
Yukinori Okada
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 65-79
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Genetic mechanisms influencing COVID-19 susceptibility are not well understood. Here, the authors analyzed whole blood RNA-seq data of 465 Japanese individuals with COVID-19, highlighting thousands of fine-mapped variants affecting expression and splicing of genes, as well as the presence of COVID-19 severity-interaction eQTLs.

Qingbo S. Wang
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-19
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

A single-cell multiomic immune cell atlas from 235 Japanese, including patients with COVID-19 and healthy individuals, linked with host genetics including germline and somatic mutation, plasma proteomics and metagenomics data reveals that immune cells are dynamically regulated in a cell state-dependent manner.

Ryuya Edahiro
Go Sato
Yukinori Okada
ResearchOpen Access28 Jul 2025
Nature Genetics

Volume: 57, P: 1905-1921
A metallo-DNA nanowire with uninterrupted one-dimensional silver array

A metallo–DNA hybrid nanowire composed only of silver-mediated base pairs has been prepared and its crystal structure resolved by X-ray diffraction. The nanowire, which is 2 nm wide and whose length reaches the μm to mm scale, holds silver ions into uninterrupted one-dimensional arrays along the DNA helical axis.

Jiro Kondo
Yoshinari Tada
Yoshiyuki Tanaka
Research03 Jul 2017
Nature Chemistry

Volume: 9, P: 956-960
Orientational Distribution of Collagen Fibers in the Horizontal Plane of Human Adult Calcaneus

Shigeyoshi Osaki
Kazuo Ohuchi
Yoshinori Takakura
Research26 Dec 2008
Polymer Journal

Volume: 41, P: 146-152
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Peripheral blood mononuclear cells from 73 Japanese patients with coronavirus disease 2019 (COVID-19) and 75 healthy controls were analyzed using single-cell transcriptomics. Combining these data with genotyping data highlights the interplay between host genetics and the immune response in modulating disease severity.

Ryuya Edahiro
Yuya Shirai
Yukinori Okada
ResearchOpen Access24 Apr 2023
Nature Genetics

Volume: 55, P: 753-767
Overview of the human genome project in Japan

Yoshiyuki Sakaki
Reviews01 Jun 1996
Japanese journal of human genetics

Volume: 41, P: 239-242
DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells

PD-L1 is upregulated in many cancers due to exogenous cellular stress. Here the authors show that PD-L1 is upregulated in response to DNA double strand breaks via STAT and IRF1 signalling.

Hiro Sato
Atsuko Niimi
Atsushi Shibata
ResearchOpen Access24 Nov 2017
Nature Communications

Volume: 8, P: 1-11
Effect of high-dose chemotherapy plus stem cell rescue on the survival of patients with neuroblastoma modified by MYCN gene gain/amplification and remission status: a nationwide registration study in Japan

Yuya Saito
Mitsuyoshi Urashima
Kimikazu Matsumoto
Research28 Apr 2021
Bone Marrow Transplantation

Volume: 56, P: 2173-2182
Phase I/II clinical trial of nivolumab in combination with oligo-fractionated irradiation for unresectable advanced or recurrent gastric cancer

Mimura et al. report findings from a single arm, phase I/II study of combined radiation and anti-PD-1 therapy in patients with advanced or recurrent gastric cancer. Combination therapy achieves a disease control rate of 22.5% for non-irradiated lesions via an abscopal effect, or 40% for irradiated lesions, and a median survival time of 230 days.

Kosaku Mimura
Takashi Ogata
Koji Kono
ResearchOpen Access15 Aug 2023
Communications Medicine

Volume: 3, P: 1-7
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer

Previous genome-wide association studies have identified risk loci for pancreatic cancer but were centered on individuals of European ancestry. Here the authors identify GP2 gene variants associated with pancreatic cancer susceptibility in populations of East Asian ancestry.

Yingsong Lin
Masahiro Nakatochi
Keitaro Matsuo
ResearchOpen Access24 Jun 2020
Nature Communications

Volume: 11, P: 1-12
Influence of skeletal muscle volume loss during lenvatinib treatment on prognosis in unresectable hepatocellular carcinoma: a multicenter study in Tohoku, Japan

Masashi Fujita
Kazumichi Abe
Hiromasa Ohira
ResearchOpen Access20 Apr 2022
Scientific Reports

Volume: 12, P: 1-10
The Liquid Crystals of Sodium Salt of Poly(glutamic acid) in Aqueous Solution

Eisaku Iizuka
Yoshiyuki Kondo
Yoshiro Ukai
Research01 Mar 1977
Polymer Journal

Volume: 9, P: 135-144
Complement activation by autoantigen recognition in the growth process of benign prostatic hyperplasia

Junya Hata
Takeshi Machida
Yoshiyuki Kojima
ResearchOpen Access30 Dec 2019
Scientific Reports

Volume: 9, P: 1-11
Low quality of life in men with chronic prostatitis-like symptoms

Mikio Sugimoto
Yasukazu Hijikata
Shunichi Fukuhara
ResearchOpen Access25 Jun 2022
Prostate Cancer and Prostatic Diseases

Volume: 25, P: 785-790
Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups

Aggregation of microtubule associated protein tau is one of cause of neuronal loss in tauopathies including Alzheimer’s disease. Here, the authors show that compounds with a 1,2-dihydroxybenzene skeleton can modify cysteine residues in tau and block toxic tau aggregation.

Yoshiyuki Soeda
Misato Yoshikawa
Akihiko Takashima
ResearchOpen Access16 Dec 2015
Nature Communications

Volume: 6, P: 1-12
Blood pressure reduction with empagliflozin in Japanese patients with type 2 diabetes and cardiovascular diseases: a post-hoc sub-analysis of the placebo-controlled randomized EMBLEM trial

Atsushi Tanaka
Michio Shimabukuro
Kunio Yufu
Research24 May 2024
Hypertension Research

Volume: 47, P: 2295-2302
Trends in the use and efficacy of adjuvant immunotherapy in muscle-invasive urothelial carcinoma

Shingo Hatakeyama
Naoki Fujita
Chikara Ohyama
ResearchOpen Access12 Jul 2025
Scientific Reports

Volume: 15, P: 1-10
Symptoms and health-related quality of life in Japanese patients with primary biliary cholangitis

Minami Yagi
Atsushi Tanaka
Hajime Takikawa
ResearchOpen Access22 Aug 2018
Scientific Reports

Volume: 8, P: 1-8
BRAF mutations in papillary carcinomas of the thyroid

Toshihiko Fukushima
Shinichi Suzuki
Seiichi Takenoshita
Research25 Sept 2003
Oncogene

Volume: 22, P: 6455-6457
Increasing incidence of acute autoimmune hepatitis: a nationwide survey in Japan

Atsushi Takahashi
Hiromasa Ohira
Hajime Takikawa
ResearchOpen Access28 Aug 2020
Scientific Reports

Volume: 10, P: 1-9
Asynchrony between Antarctic temperature and CO₂ associated with obliquity over the past 720,000 years

The Antarctic temperature record displays a puzzling asynchrony with changes in CO₂ through glacial cycles. Here, the authors show that a 720,000-year Antarctic temperature record is affected by variations in obliquity-induced local insolation that are associated with phase modulation of eccentricity cycle.

Ryu Uemura
Hideaki Motoyama
Yoshiyuki Fujii
ResearchOpen Access06 Mar 2018
Nature Communications

Volume: 9, P: 1-11
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Role of puboperinealis and rectourethralis muscles as a urethral support system to maintain urinary continence after robot-assisted radical prostatectomy

Masao Kataoka
Satoru Meguro
Yoshiyuki Kojima
ResearchOpen Access29 Aug 2023
Scientific Reports

Volume: 13, P: 1-10
Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Youngjune Bhak
Vasilis Raptis
Albert Tenesa
ResearchOpen Access28 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
Publisher Correction: Defective Epstein–Barr virus in chronic active infection and haematological malignancy

Yusuke Okuno
Takayuki Murata
Hiroshi Kimura
Amendments and Corrections30 Jan 2019
Nature Microbiology

Volume: 4, P: 544
Tetrahydrobiopterin prevents chronic ischemia-related lower urinary tract dysfunction through the maintenance of nitric oxide bioavailability

Hidenori Akaihata
Junya Hata
Yoshiyuki Kojima
ResearchOpen Access16 Nov 2020
Scientific Reports

Volume: 10, P: 1-10
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
A new model to estimate duration of survival in patients with hepatocellular carcinoma with BCLC intermediate stage

Masashi Ninomiya
Mio Tsuruoka
Atsushi Masamune
ResearchOpen Access25 Nov 2023
Scientific Reports

Volume: 13, P: 1-8
Defective Epstein–Barr virus in chronic active infection and haematological malignancy

Genome sequencing of fractionated T-, B- and natural killer cells from patients with chronic active Epstein–Barr virus (EBV) infection sheds light on the nature of the EBV-infected progenitor and suggests a link between intragenic EBV deletions and EBV-associated neoplastic proliferations.

Yusuke Okuno
Takayuki Murata
Hiroshi Kimura
Research21 Jan 2019
Nature Microbiology

Volume: 4, P: 404-413
Blood pressure during long-term cilostazol-based dual antiplatelet therapy after stroke: a post hoc analysis of the CSPS.com trial

Kazunori Toyoda
Masatoshi Koga
Hiroaki Tanaka
ResearchOpen Access09 Jul 2024
Hypertension Research

Volume: 47, P: 2238-2249
Artificial intelligence support improves diagnosis accuracy in anterior segment eye diseases

Hiroki Maehara
Yuta Ueno
Tetsuro Oshika
ResearchOpen Access11 Feb 2025
Scientific Reports

Volume: 15, P: 1-10
Quantitative analysis of gastrointestinal fluid absorption and secretion to estimate luminal fluid dynamics in rats

Yuta Funai
Kazuki Ichijo
Yoshiyuki Shirasaka
ResearchOpen Access14 Oct 2023
Scientific Reports

Volume: 13, P: 1-9
Performance and usefulness of a novel automated immunoassay HISCL SARS-CoV-2 Antigen assay kit for the diagnosis of COVID-19

Kaori Saito
Tomohiko Ai
Yoko Tabe
ResearchOpen Access01 Dec 2021
Scientific Reports

Volume: 11, P: 1-10
Air pollution significantly associated with severe ocular allergic inflammatory diseases

Dai Miyazaki
Kazumi Fukagawa
Yoshitsugu Inoue
ResearchOpen Access03 Dec 2019
Scientific Reports

Volume: 9, P: 1-9
ROCK inhibitor combined with Ca²⁺ controls the myosin II activation and optimizes human nasal epithelial cell sheets

Yoshiyuki Kasai
Tsunetaro Morino
Hiromi Kojima
ResearchOpen Access08 Oct 2020
Scientific Reports

Volume: 10, P: 1-13
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Hiroki Masuda
Masahiro Mori
Satoshi Kuwabara
ResearchOpen Access03 Aug 2023
Scientific Reports

Volume: 13, P: 1-14
The importance of clinical experience in AI-assisted corneal diagnosis: verification using intentional AI misleading

Hiroki Maehara
Yuta Ueno
Tetsuro Oshika
ResearchOpen Access09 Jan 2025
Scientific Reports

Volume: 15, P: 1-9
POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33

Yuki Hitomi
Kazuko Ueno
Minoru Nakamura
ResearchOpen Access14 Jan 2019
Scientific Reports

Volume: 9, P: 1-11
The prevalence and clinical features of MYO7A-related hearing loss including DFNA11, DFNB2 and USH1B

Kizuki Watanabe
Shin-ya Nishio
Shunsuke Kondo
ResearchOpen Access09 Apr 2024
Scientific Reports

Volume: 14, P: 1-19
Efficacy of elotuzumab for multiple myeloma in reference to lymphocyte counts and kappa/lambda ratio or B2 microglobulin

Yutaka Shimazu
Junya Kanda
Junya Kuroda
ResearchOpen Access29 Mar 2023
Scientific Reports

Volume: 13, P: 1-12
A non-carboxylating pentose bisphosphate pathway in halophilic archaea

A nucleoside degradation pathway in halophilic archaea is identified, which converts the ribose moiety of guanosine to dihydroxyacetone phosphate and ethylene glycol.

Takaaki Sato
Sanae (Hodo) Utashima
Haruyuki Atomi
ResearchOpen Access24 Nov 2022
Communications Biology

Volume: 5, P: 1-13
Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank

Aye Ko Ko Minn
Motomichi Matsuzaki
Gen Tamiya
ResearchOpen Access03 Apr 2025
Journal of Human Genetics

Volume: 70, P: 287-296

Previous page
page 1
page 2
Next page

Search

Search articles by subject, keyword or author

Show results from

Advanced search

Quick links

Explore articles by subject
Find a job
Guide to authors
Editorial policies

Nature.com

nature.com sitemap

About Nature Portfolio

About us
Press releases
Press office
Contact us

Discover content

Journals A-Z
Articles by subject
protocols.io
Nature Index

Publishing policies

Nature portfolio policies
Open access

Author & Researcher services

Reprints & permissions
Research data
Language editing
Scientific editing
Nature Masterclasses
Research Solutions

Libraries & institutions

Librarian service & tools
Librarian portal
Open research
Recommend to library

Advertising & partnerships

Advertising
Partnerships & Services
Media kits
Branded content

Professional development

Nature Awards
Nature Careers
Nature Conferences

Regional websites

Nature Africa
Nature China
Nature India
Nature Japan
Nature Middle East

Privacy Policy
Use of cookies
Legal notice
Accessibility statement
Terms & Conditions
Your US state privacy rights

© 2026 Springer Nature Limited