Adverse aortic remodeling after thoracic endovascular aortic repair elevates the risk of aorta-related adverse events and worsens overall prognosis in aortic dissection (AD), highlighting the need for prognostic indicators and therapeutic targets to enhance TEVAR efficacy. Here, the authors show that inhibiting neutrophil extracellular traps ameliorates the progression of AD in mice, and that citrullinated histone H3 facilitates the risk stratification and prognostic evaluation of patients with AD.
- Yu-Fei Zhao
- Zi-Ang Zuo
- Li-Xin Wang