Nature Search

Targeting SLC7A5 in lung squamous cell carcinoma: implications for cancer metabolism shift and boron neutron capture therapy resistance

Yen-Ju Lin
Yu-Cheng Wu
Yu-Ting Chou
ResearchOpen Access23 Jul 2025
Oncogenesis

Volume: 14, P: 1-13
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer

Remaining drug-tolerant persistent (DTP) cancer cells limit the efficacy of targeted therapy in EGFR, ALK and KRAS mutant non-small cell lung cancer (NSCLC). Here, the authors show that focal adhesion kinase (FAK)-YAP signalling supports DTP cells promoting residual disease and targeting this pathway improved tumour response in NSCLC preclinical models.

Franziska Haderk
Yu-Ting Chou
Trever G. Bivona
ResearchOpen Access03 May 2024
Nature Communications

Volume: 15, P: 1-19
Effects of dexmedetomidine on surgery for type A acute aortic dissection outcome

Yu-Ting Cheng
Kuang-Tso Lee
Shao-Wei Chen
ResearchOpen Access17 Feb 2022
Scientific Reports

Volume: 12, P: 1-7
ATOH1/RFX1/RFX3 transcription factors facilitate the differentiation and characterisation of inner ear hair cell-like cells from patient-specific induced pluripotent stem cells harbouring A8344G mutation of mitochondrial DNA

Yen-Chun Chen
Chia-Ling Tsai
Yi-Chao Hsu
ResearchOpen Access19 Apr 2018
Cell Death & Disease

Volume: 9, P: 1-15
Levobuipivacaine-Induced Dissemination of A549 Lung Cancer Cells

Shun-Ming Chan
Bo-Feng Lin
Zhi-Fu Wu
ResearchOpen Access17 Aug 2017
Scientific Reports

Volume: 7, P: 1-8
Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds

Synthesis of new vancomycin-like glycopeptides offers opportunities to overcome antibiotic resistance. The crystallographic identification of a reaction intermediate close to the surface of a glycopeptide tailoring enzyme leads to a new biocatalytic strategy to create two classes of teicoplanin analogs.

Yu-Chen Liu
Yi-Shan Li
Tsung-Lin Li
Research10 Apr 2011
Nature Chemical Biology

Volume: 7, P: 304-309
Addendum: Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds

Yu-Chen Liu
Yi-Shan Li
Tsung-Lin Li
Amendments and Corrections17 Apr 2015
Nature Chemical Biology

Volume: 11, P: 361
The regulatory activity of microRNA^* species has substantial influence on microRNA and 3′ UTR evolution

Katsutomo Okamura
Michael D Phillips
Eric C Lai
Research30 Mar 2008
Nature Structural & Molecular Biology

Volume: 15, P: 354-363
Cytokine and epigenetic regulation of CEACAM6 mediates EGFR-driven signaling and drug response in lung adenocarcinoma

Ming-Yi Zheng
Yen-Ting Lin
Yu-Ting Chou
ResearchOpen Access22 Apr 2025
npj Precision Oncology

Volume: 9, P: 1-15
Cardiothoracic ratio values and trajectories are associated with risk of requiring dialysis and mortality in chronic kidney disease

Chou et al. develop a machine learning algorithm for the automated determination of cardiothoracic ratio (CTR). Both baseline CTRs and trajectories of serial CTR measurements are associated with end-stage renal disease and mortality in patients with chronic kidney disease.

Che-Yi Chou
Charles C. N. Wang
Chin-Chi Kuo
ResearchOpen Access07 Feb 2023
Communications Medicine

Volume: 3, P: 1-8
Genetic ancestry plays a central role in population pharmacogenomics

Hsin-Chou Yang et al. examine population structure in several genomic databases and identify that pharmacogenetic loci are enriched for markers of genetic ancestry. Their results suggest that genetic ancestry must be carefully considered in population pharmacogenetics studies.

Hsin-Chou Yang
Chia-Wei Chen
Shih-Kai Chu
ResearchOpen Access05 Feb 2021
Communications Biology

Volume: 4, P: 1-14
Crosstalk between SOX2 and cytokine signaling in endometrial carcinoma

Chang-Jung Lee
Pi-Lin Sung
Yu-Ting Chou
ResearchOpen Access03 Dec 2018
Scientific Reports

Volume: 8, P: 1-12
Endothelial cell colony forming units derived from malignant breast diseases are resistant to tumor necrosis factor-α-induced apoptosis

Chen-Pin Chou
Shih Sheng Jiang
Ya-Wen Chen
ResearchOpen Access24 Nov 2016
Scientific Reports

Volume: 6, P: 1-12
Topographic effect on the phenology of Ficus pedunculosa var. mearnsii (Mearns fig) in its northern boundary distribution, Taiwan

Chu-Chia Kuo
Anthony Bain
Hsy-Yu Tzeng
ResearchOpen Access07 Nov 2017
Scientific Reports

Volume: 7, P: 1-11
Critical role of SOX2–IGF2 signaling in aggressiveness of bladder cancer

Yu-Fan Chiu
Chia-Chang Wu
Yu-Ting Chou
ResearchOpen Access19 May 2020
Scientific Reports

Volume: 10, P: 1-13
Nearby fault interaction within the double-vergence suture in eastern Taiwan during the 2022 Chihshang earthquake sequence

Slip on one of two conjugate thrust faults can influence the Coulomb stress and subsequent slip behaviour on the other, according to field and satellite observations of the Central Range fault and the Longitudinal Valley fault in Eastern Taiwan.

Chi-Hsien Tang
Yunung Nina Lin
Horng-Yue Chen
ResearchOpen Access21 Sept 2023
Communications Earth & Environment

Volume: 4, P: 1-12
Learning curve for open surgical repair of acute type A aortic dissection

Bo-Cheng Hou
Yu-Tung Huang
Shao-Wei Chen
ResearchOpen Access03 Mar 2023
Scientific Reports

Volume: 13, P: 1-10
Tumor suppressor p53 restrains cancer cell dissemination by modulating mitochondrial dynamics

Trinh T. T. Phan
Yu-Chun Lin
Lih-Yuan Lin
ResearchOpen Access19 May 2022
Oncogenesis

Volume: 11, P: 1-14
Cyproterone acetate acts as a disruptor of the aryl hydrocarbon receptor

Chih-Shou Chen
Guan-Lun Gao
Jyan-Gwo Joseph Su
ResearchOpen Access09 Mar 2021
Scientific Reports

Volume: 11, P: 1-12
Association of Divergent Carcinoembryonic Antigen Patterns and Lung Cancer Progression

Yen-Shou Kuo
Ming-Yi Zheng
Yu-Ting Chou
ResearchOpen Access07 Feb 2020
Scientific Reports

Volume: 10, P: 1-10
OCT4B mediates hypoxia-induced cancer dissemination

Sheng-Chieh Lin
Chi-Hsiu Chung
Cheng-Wen Wu
Research12 Sept 2018
Oncogene

Volume: 38, P: 1093-1105
OPRM1 genetic polymorphisms are associated with the plasma nicotine metabolite cotinine concentration in methadone maintenance patients: a cross sectional study

Yu-Ting Chen
Hsiao-Hui Tsou
Yu-Li Liu
Research06 Dec 2012
Journal of Human Genetics

Volume: 58, P: 84-90

Search

Targeting SLC7A5 in lung squamous cell carcinoma: implications for cancer metabolism shift and boron neutron capture therapy resistance

Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer

Effects of dexmedetomidine on surgery for type A acute aortic dissection outcome

ATOH1/RFX1/RFX3 transcription factors facilitate the differentiation and characterisation of inner ear hair cell-like cells from patient-specific induced pluripotent stem cells harbouring A8344G mutation of mitochondrial DNA

Levobuipivacaine-Induced Dissemination of A549 Lung Cancer Cells

Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds

Addendum: Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds

The regulatory activity of microRNA^* species has substantial influence on microRNA and 3′ UTR evolution

Cytokine and epigenetic regulation of CEACAM6 mediates EGFR-driven signaling and drug response in lung adenocarcinoma

Cardiothoracic ratio values and trajectories are associated with risk of requiring dialysis and mortality in chronic kidney disease

Genetic ancestry plays a central role in population pharmacogenomics

Crosstalk between SOX2 and cytokine signaling in endometrial carcinoma

Endothelial cell colony forming units derived from malignant breast diseases are resistant to tumor necrosis factor-α-induced apoptosis

Topographic effect on the phenology of Ficus pedunculosa var. mearnsii (Mearns fig) in its northern boundary distribution, Taiwan

Critical role of SOX2–IGF2 signaling in aggressiveness of bladder cancer

Nearby fault interaction within the double-vergence suture in eastern Taiwan during the 2022 Chihshang earthquake sequence

Learning curve for open surgical repair of acute type A aortic dissection

Tumor suppressor p53 restrains cancer cell dissemination by modulating mitochondrial dynamics

Cyproterone acetate acts as a disruptor of the aryl hydrocarbon receptor

Association of Divergent Carcinoembryonic Antigen Patterns and Lung Cancer Progression

OCT4B mediates hypoxia-induced cancer dissemination

OPRM1 genetic polymorphisms are associated with the plasma nicotine metabolite cotinine concentration in methadone maintenance patients: a cross sectional study

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